Results 151 to 160 of about 216,203 (306)

Mechanisms for the effect of electric and magnetic fields on biological systems Semiannual status report, Jun. - Dec. 1969 [PDF]

Electric and magnetic field effects on structure and properties of cholesteric liquid ...
Baessler, H., Labes, M. M., Laronge, T. M., Teucher, I.   +3 more
core   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption. [PDF]

Sci Adv, 2021
Long T, Liu Y, Qin Y, DeBose-Boyd RA, Li X.   +4 more
europepmc   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis. [PDF]

J Atheroscler Thromb, 2022
Shoji T, Akiyama Y, Fujii H, Harada-Shiba M, Ishibashi Y, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsuki K, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H.   +22 more
europepmc   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

Markers of cholesterol synthesis to cholesterol absorption across the spectrum of non-dialysis CKD: An observational study. [PDF]

Pharmacol Res Perspect, 2021
Emrich IE, Heine GH, Schulze PC, Rogacev KS, Fliser D, Wagenpfeil S, Böhm M, Lütjohann D, Weingärtner O.   +8 more
europepmc   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Associations between SNPs in Intestinal Cholesterol Absorption and Endogenous Cholesterol Synthesis Genes with Cholesterol Metabolism. [PDF]

Biomedicines, 2021
Schroor MM, Mokhtar FBA, Plat J, Mensink RP.   +3 more
europepmc   +1 more source

Mechanism of Cholesterol Absorption

Journal of Biological Chemistry, 1958
Leon Swell, E.C. Trout, J.R. Hopper, Henry Field, C.R. Treadwell   +4 more
openaire   +1 more source