Results 231 to 240 of about 93,050 (306)

Effects of phytoestrogens on the reproduction and weight regulation of mammals [PDF]

Ryökkynen, Ari
core  

Volatile compounds formed during heating of asymmetric distigmasterol-modified acylglycerols as indicators of thermo-oxidative degradation. [PDF]

Sci Rep
Grygier A, Rudzińska M, Kmiecik D, Grudniewska A.   +3 more
europepmc   +1 more source

Macrophage‐Specific Loss of Stearoyl‐CoA Desaturase 1 Promotes Colon Cancer by Enhancing M2 TAM Polarization

Cancer Science, EarlyView.
Macrophage‐specific Scd1 deletion accelerates colon cancer progression by suppressing the Hippo‐YAP pathway, which drives immunosuppressive M2 polarization and induces CD8+ T cell exhaustion. Pharmacological YAP activation with TT‐10 effectively reverses this microenvironment, highlighting a promising target for immunotherapy. ABSTRACT In colon cancer (
Qing You, Jiaqi Du, Ziran Wei, Yandong Liu, Weijun Wang, Wenchao Gao   +5 more
wiley   +1 more source

Exploring sex bias in cardiometabolic diseases. [PDF]

Lipids Health Dis
Guillemette T, Rhainds D, Robert O, Mounier C.   +3 more
europepmc   +1 more source

Absorption and Effects of Patch Test Preparations of Hydroperoxides of Limonene and Hydroperoxides of Linalool in Human Ex Vivo Skin

Contact Dermatitis, EarlyView.
This study mimics clinical patch testing for the diagnosis of allergic contact dermatitis, by application of patch test preparations of fragrance terpenes to ex vivo human skin samples. The study investigates the penetration of linalool hydroperoxide and limonene hydroperoxide in skin, alongside an analysis of the lipid‐modifying effects of the patch ...
Aoife Clancy, Lina Hagvall, Per Malmberg, Niamh M. O'Boyle   +3 more
wiley   +1 more source

Metabolomic Atlas of Cardiovascular Diseases: Mapping Shared and Specific Signatures. [PDF]

JACC Adv
Yang J, Ning W, Xu R, Guo Y, He A, Fan J, Wang Y, Li X, Chen Q.   +8 more
europepmc   +1 more source

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

Meibum Lipid Saturation Related to Dry Eye, Age, and Sex Using Nuclear Magnetic Resonance Spectroscopy. [PDF]

Invest Ophthalmol Vis Sci
Machane D, Shaji MS, Borchman D, Jaeger V.   +3 more
europepmc   +1 more source

Cold‐Induced Lipidomic Remodelling Is Associated With Brown Adipose Tissue Mean Radiodensity in Humans

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Cold exposure activates brown adipose tissue (BAT) and promotes thermogenic and metabolic adaptations. While BAT activation has been linked to improved cardiometabolic health, how acute cold exposure reshapes the circulating lipidome in humans remains incompletely understood.
Yu Zhang, Borja Martinez‐Tellez, Alida Kindt, Nicolas Drouin, Amy Harms, Thomas Hankemeier, Jonatan R. Ruiz, Lucas Jurado‐Fasoli   +7 more
wiley   +1 more source

Plasma complex lipids in relation to cortical thickness and brain volumes: results from the population-based Rhineland study. [PDF]

Lipids Health Dis
Landstra EN, Lohner V, Tavares JF, Diers K, Koch A, Breteler MMB.   +5 more
europepmc   +1 more source