Results 31 to 40 of about 586,832 (295)

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu, Mincheng Lu, Ruiyi He, Ruiyi He, Chao Li, Chao Li, Zixian Liu, Zixian Liu, Yuhui Chen, Yuhui Chen, Bingsheng Yang, Bingsheng Yang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Metabolism of low-density lipoproteins by cultured hepatocytes from normal and homozygous familial hypercholesterolemic subjects [PDF]

, 1986
The profoundly elevated concentrations of low-density lipoproteins (LDL) present in homozygous familial hypercholesterolemia lead to symptomatic cardiovascular disease and death by early adulthood.
Brewer, HB, Demosky, SJ, Edge, SB, Gregg, RE, Hoeg, JM, Starzl, TE, Triche, T   +6 more
core   +1 more source

Long Term Anticoagulation (4–16 Years) Stops Progression of Idiopathic Hip Osteonecrosis Associated with Familial Thrombophilia

Advances in Orthopedics, 2015
In 6 patients with familial thrombophilia (5 Factor V (FV) Leiden heterozygotes, 1 with resistance to activated protein C (RAPC)), we prospectively assessed whether continuous longterm (4–16 years) anticoagulation would prevent progression of idiopathic ...
Charles J. Glueck, Richard A. Freiberg, Robert Wissman, Ping Wang   +3 more
doaj   +1 more source

HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of Anethum Graveolens, Pimpinella Anisum, and Ferulago Campestris

Molecules, 2019
Umbelliprenin has recently been shown to have great potential as a skin whitening agent. Wishing to investigate the same effect in plant species known to biosynthesize this coumarin, three plants belonging to the Apiaceae family, namely Anethum ...
Vito Alessandro Taddeo, Francesco Epifano, Francesca Preziuso, Serena Fiorito, Nicolas Caron, Arnaud Rives, Philippe de Medina, Marc Poirot, Sandrine Silvente-Poirot, Salvatore Genovese   +9 more
doaj   +1 more source

Sorting through the extensive and confusing roles of sortilin in metabolic disease

Journal of Lipid Research, 2022
Sortilin is a post-Golgi trafficking receptor homologous to the yeast vacuolar protein sorting receptor 10 (VPS10). The VPS10 motif on sortilin is a 10-bladed β-propeller structure capable of binding more than 50 proteins, covering a wide range of ...
Kelly A. Mitok, Mark P. Keller, Alan D. Attie   +2 more
doaj   +1 more source

Adropin: An endocrine link between the biological clock and cholesterol homeostasis [PDF]

, 2018
This article explores two translation models circling around the key issue “equivalence” in translation studies. They are the Jerome Model and the Horace Model. They differentiate from each other in the aspects of the translating priorities and purposes,
et al,, Rao, D. C
core   +4 more sources

Ubiquitin Ligases in Cholesterol Metabolism [PDF]

Diabetes & Metabolism Journal, 2014
To maintain cholesterol homeostasis, the processes of cholesterol metabolism are regulated at multiple levels including transcription, translation, and enzymatic activity.
Wei Jiang, Bao-Liang Song
doaj   +1 more source

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]

, 2017
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H., Charles, Philip D., Dowle, Adam A., Geoghegan, Vincent, Hester, Svenja, Larson, Tony, Rainey, Stephanie M., Sinkins, Steven P., Stainton, Kirsty, Thomas, Benjamin   +9 more
core   +3 more sources

Cholesterol metabolism: increasingly complex

Grasas y Aceites, 2012
Cholesterol is an important molecule; it is necessary for the biosynthesis of steroidal hormones, bile salts and to maintain the stability of biological membranes in animal cells.
J. Sanhueza, R. Valenzuela, A. Valenzuela   +2 more
doaj   +1 more source

Multiplex immunohistochemistry defines two cholesterol metabolism patterns predicting immunotherapeutic outcomes in gastric cancer

Journal of Translational Medicine, 2023
Background The role of cholesterol metabolism in gastric cancer (GC) and its implications for tumor characteristics and immunotherapy response remain poorly understood.
Wei Tang, Guanghua Li, Qi Lin, Zhenzhen Zhu, Zhao Wang, Zhixiong Wang   +5 more
doaj   +1 more source