Results 261 to 270 of about 441,731 (309)

Relationships between dietary cholesterol, cholesterol absorption, cholesterol synthesis, and plasma cholesterol in rhesus monkeys

Atherosclerosis, 1987
The relationships between the cholesterol content of the diet, plasma cholesterol concentration, cholesterol absorption, and cholesterol synthesis (measured indirectly by desmosterol suppression technique) are explored in groups of high- and low-responding rhesus monkeys fed diets containing 0.02, 0.15 and 0.75 mg cholesterol/kcal.
A K, Bhattacharyya, D A, Eggen
openaire   +2 more sources

Metabolite Regulation of Cholesterol Synthesis

Hospital Practice, 1985
Strong circumstantial evidence supports the concept that 26-hydroxycholesterol is involved in regulating synthesis of its parent molecule. Different theories of feedback inhibition of a critical enzyme, HMG-CoA reductase, are discussed. Advances in mass spectrometry technology should make it possible to establish whether cholesterol or its metabolite ...
openaire   +2 more sources

Disorders of Isoprenoid/Cholesterol Synthesis

2016
Ten different enzyme defects in the isoprenoid/cholesterol synthetic pathway have been linked with different genetic disorders. Of these, mevalonate kinase deficiency affects the synthesis of all isoprenoids, is associated characteristically with recurrent episodes of high fever and inflammation, and may present with congenital anomalies.
Waterham, Hans R., Clayton, Peter T.
openaire   +1 more source

Fat feeding and cholesterol synthesis

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1967
Abstract The feeding of fat has previously been shown to result in a decrease in fatty acid synthesis and an increase in cholesterol synthesis by the liver. Furthermore, it has been proposed that fatty acid synthesis is controlled by the inhibition of the ratelimiting acetyl-CoA carboxylase by long-chain fatty acyl-CoA derivatives with a consequent ...
openaire   +2 more sources

Cholesterol synthesis

2021
Andrew J. Brown, Hudson W. Coates, Laura J. Sharpe   +2 more
openaire   +1 more source

Disorders of Cholesterol Synthesis

2000
Only four of over 30 possible defects of cholesterol biosynthesis have been described. Mevalonic aciduria due to mevalonate kinase deficiency is situated at the beginning of the pathway and compromises the production of nonsterol isoprenes in addition to cholesterol.
Georg F. Hoffmann, Dorothea Haas
openaire   +1 more source

[Lowering cholesterol 1998. Cholesterol synthesis inhibitors compared].

Wiener klinische Wochenschrift, 1999
Large scale primary and secondary prevention trials in recent years have revealed that the effective lipid reducing therapy with statins can reduce mortality of coronary heart disease by up to 30%. For the first time it has become possible to reduce LDL-cholesterol pharmacologically by more than 50%, a reduction that was only achieved by LDL-apheresis ...
K M, Kostner, G M, Kostner
openaire   +1 more source

CHOLESTEROL SYNTHESIS AND HYPERCHOLESTEROLEMIA

JAMA: The Journal of the American Medical Association, 1926
InThe Journal, Oct. 3, 1925, page 1066, an editorial appears entitled "The Synthesis of Cholesterol in the Body." It is indicated therein that feeding experiments have shown that cholesterol need not have its source exclusively in the diet. We submit further evidence on this point in the form of Dezani's work ( Arch. di farmacol. sper.
openaire   +1 more source

KETOCONAZOLE AND CHOLESTEROL SYNTHESIS

The Lancet, 1984
T A, Miettinen, V V, Valtonen
openaire   +2 more sources

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly