Results 21 to 30 of about 274,133 (264)

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men

Journal of Lipid Research, 2004
Type 2 diabetes has been associated with high synthesis and low absorption of cholesterol independent of weight, indicating that insulin resistance may be a link between glucose and cholesterol metabolism.
Jussi Pihlajamäki, Helena Gylling, Tatu A. Miettinen, Markku Laakso   +3 more
doaj   +1 more source

Evaluation of the use of serum lathosterol concentration to assess whole-body cholesterol synthesis in rabbits.

Journal of Lipid Research, 1992
Serum lathosterol concentration in rabbits was assessed as a possible indicator of whole-body cholesterol synthesis. In random-bred New Zealand White (NZW) rabbits fed a control diet or a diet containing either cholesterol, simvastatin, or cholestyramine,
GW Meijer, JG Van der Palen, H De Vries, HJ Kempen, HA Van der Voort, LF Van Zutphen, AC Beynen   +6 more
doaj   +1 more source

Cholesterol metabolism in hypothyroidism and hyperthyroidism in man.

Journal of Lipid Research, 1981
Studies were carried out on cholesterol metabolism in 11 nonobese patients and 16 obese patients with hypothyroidism and 13 with hyperthyroidism. The patients underwent several investigations under metabolic ward conditions.
J J Abrams, S M Grundy
doaj   +1 more source

Diurnal and dietary-induced changes in cholesterol synthesis correlate with levels of mRNA for HMG-CoA reductase

Journal of Lipid Research, 2000
We determined the extent to which diurnal variation in cholesterol synthesis in liver is controlled by steady-state mRNA levels for the rate-limiting enzyme in the pathway, hydroxymethylglutaryl (HMG)-CoA reductase.
Helga Jurevics, Janell Hostettler, Cheri Barrett, Pierre Morell, Arrel D. Toews   +4 more
doaj   +1 more source

Evolution, Expression Profile, Regulatory Mechanism, and Functional Verification of EBP-Like Gene in Cholesterol Biosynthetic Process in Chickens (Gallus Gallus)

Frontiers in Genetics, 2021
The emopamil binding protein (EBP) is an important enzyme participating in the final steps of cholesterol biosynthesis in mammals. A predictive gene EBP-like, which encodes the protein with a high identity to human EBP, was found in chicken genome.
Keren Jiang, Zheng Ma, Zheng Ma, Zhang Wang, Hong Li, Hong Li, Hong Li, Yanbin Wang, Yanbin Wang, Yanbin Wang, Yadong Tian, Yadong Tian, Yadong Tian, Donghua Li, Donghua Li, Donghua Li, Xiaojun Liu, Xiaojun Liu, Xiaojun Liu   +18 more
doaj   +1 more source

The interaction of cholesterol absorption and cholesterol synthesis in man

Journal of Lipid Research, 1969
The total miscible pool of cholesterol in the body is determined largely by the interaction of cholesterol absorption and synthesis. In the present study we have examined the net effects of this interplay in one normal and five hypercholesteremic subjects when various amounts of cholesterol were made available for absorption.
Scott M. Grundy, E.H. Ahrens, Jr., Jean Davignon   +2 more
openaire   +3 more sources

Cholesterol synthesis in the perfused liver of pregnant hamsters

Journal of Lipid Research, 1987
Pregnancy is a risk factor for the development of cholesterol gallstones. In pregnant women, biliary cholesterol saturation and secretion are increased.
J Reichen, G Karlaganis, F Kern, Jr
doaj   +1 more source

Effect of evolocumab on cholesterol synthesis and absorption[S]

Journal of Lipid Research, 2016
The effects of cholesterol-lowering drugs, including those that reduce cholesterol synthesis (statins) and those that reduce cholesterol absorption (ezetimibe), on cholesterol absorption and synthesis are well understood. Proprotein convertase subtilisin/
Matthew Peach, Ren Xu, Dan Fitzpatrick, Lisa Hamilton, Ransi Somaratne, Robert Scott, Scott M. Wasserman, C. Stephen Djedjos   +7 more
doaj   +1 more source

Effects of dietary cholesterol on the regulation of total body cholesterol in man

Journal of Lipid Research, 1971
Studies on the interaction of cholesterol absorption, synthesis, and excretion were carried out in eight patients using sterol balance techniques. Absorption of dietary cholesterol was found to increase with intake; up to 1 g of cholesterol was absorbed ...
EDER QUINTÃO, SCOTT M. GRUNDY, E.H. AHRENS, JR.   +2 more
doaj   +1 more source

Origin of biliary cholesterol and lecithin in the rat: contribution of new synthesis and preformed hepatic stores.

Journal of Lipid Research, 1982
The contribution of de novo synthesis to the secretion of cholesterol and lecithin in bile was assessed in isolated rat livers, perfused with a lipid-free medium.
S J Robins, H Brunengraber
doaj   +1 more source