Results 71 to 80 of about 254,209 (239)

Cholesteryl ester transfer protein and hyperalphalipoproteinemia in Caucasians [PDF]

Journal of Lipid Research, 2007
It is unclear whether cholesteryl ester transfer protein (CETP) contributes to high density lipoprotein cholesterol (HDL-C) levels in hyperalphalipoproteinemia (HALP) in Caucasians. Moreover, even less is known about the effects of hereditary CETP deficiency in non-Japanese. We studied 95 unrelated Caucasian individuals with HALP.
van der Steeg, Wim A., Hovingh, G. Kees, Klerkx, Anke H. E. M., Hutten, Barbara A., Nootenboom, Inge C., Levels, Johannes H. M., van Tol, Arie, Dallinga-Thie, Gees M., Zwinderman, Aeilko H., Kastelein, John J. P., Kuivenhoven, Jan Albert   +10 more
openaire   +3 more sources

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

CHOLESTEROL AND CHOLESTERYL ESTER CONTENT IN NORMAL AND PATHOLOGIC SCALE [PDF]

, 1977
Using a sensitive new assay, we have measured the cholesteryl ester and cholesterol contents of stratum corneum from callus, normal skin, psoriatic lesions (plantar and nonplantar), and lamellar ichthyotic lesions (plantar and nonplantar).
Kiem, Iris, Penneys, Neal S, Ziboh, Vincent A, Schlossberg, Jeanne, Schmidt, Charles   +4 more
core   +1 more source

Distribution of cell-derived cholesterol among plasma lipoproteins: a comparison of three techniques.

Journal of Lipid Research, 1990
Three fractionation procedures (immunoaffinity chromatography, two-dimensional nondenaturing electrophoresis, and heparin-agarose affinity chromatography) have been compared in determining the kinetics of free and ester cholesterol transfer in ...
OL Francone, CJ Fielding, PE Fielding
doaj   +1 more source

Anaerobic degradation kinetics of a cholesteryl ester

Water Science and Technology, 2003
The most important components of wool scouring effluent grease are esters of sterols. Cholesteryl palmitate (CP) is the main ester in this grease. In this paper, the influence of the ester concentration in the anaerobic digestion and the relative rate of the different degradation steps, are studied.
S, Gutiérrez, M, Viñas
openaire   +2 more sources

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, EarlyView.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source

PerMΦs from db/db mice have increased AcLDL and cholesteryl ester uptake.

, 2013
A, db/+and db/db mice were administered 5 µg/mL of Dil-AcLDL by IP injection. After 4 h, PerMΦs were collected and Dil-AcLDL uptake measured by flow cytometry.
Matthew E. Hartman (30548), Jason C. O'Connor (30549), Kenneth S. Chakour (30550), Gregory G. Freund (30552), Ali A. Sovari (30551), Christopher B. Guest (30547)   +5 more
core   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source

Detection of Liquid Phase Cholesteryl Ester in Carotid Atherosclerosis by 1H-MR Spectroscopy in Humans [PDF]

, 2013
ObjectivesThis study hypothesized that 1H magnetic resonance spectroscopy (1H-MRS) can identify carotid plaque cholesteryl ester in vivo in humans.BackgroundLiquid phase cholesteryl ester comprises a major fraction of atherosclerotic plaque, and its ...
Duivenvoorden, Raphaël, Kastelein, John J.P., Klimas, Michael, Nederveen, Aart J., van Wijk, Diederik, Stroes, Erik S.G., Stroes, Erik S. G., Kastelein, John J. P.   +7 more
core   +1 more source