Results 181 to 190 of about 7,033,015 (228)
Cholesteryl Ester Transfer Protein, CETP
The Journal of Japan Atherosclerosis Society, 1996 openaire +2 more sources
European Journal of Clinical Investigation, 1990 The activity of cholesteryl ester transfer protein is instrumental in the distribution of cholesteryl ester between lipoproteins in plasma. We measured the activity of cholesteryl ester transfer protein in plasma, designated cholesteryl ester transfer ...
J E Groener +2 more
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Atherosclerosis, 1998 Lecithin:cholesteryl acyl transferase (LCAT) and cholesteryl ester transfer protein (CETP) are key factors in the esterification of cholesterol and the subsequent transfer of cholesteryl ester from high density lipoproteins (HDL) towards very low and low
Robin P F Dullaart +2 more
exaly +3 more sources
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Cholesteryl ester transfer protein and atherosclerosis
Current Opinion in Lipidology, 2000Plasma cholesteryl ester transfer protein facilitates the transfer of cholesteryl ester from HDL to apolipoprotein B-containing lipoproteins. Its significance in atherosclerosis has been debated in studies of human population genetics and transgenic mice.
A, Inazu, J, Koizumi, H, Mabuchi
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Lipids, 1990
AbstractA lipid transfer protein complex (LTC), purified from human plasma by immunoaffinity chromatography, catalyzed the interlipoprotein transfer of cholesteryl esters (CE) and triglycerides (TG). The CE transfer activity of LTC was governed by the strucutre of the CE. Incubation of LTC with long chain CE both activated and stabilized LTC.
S J, Busch, J A, Harmony
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AbstractA lipid transfer protein complex (LTC), purified from human plasma by immunoaffinity chromatography, catalyzed the interlipoprotein transfer of cholesteryl esters (CE) and triglycerides (TG). The CE transfer activity of LTC was governed by the strucutre of the CE. Incubation of LTC with long chain CE both activated and stabilized LTC.
S J, Busch, J A, Harmony
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Cholesteryl Ester Transfer Protein in Human Brain
International Journal of Clinical and Laboratory Research, 1992The evidence that apolipoproteins are found in the cerebrospinal fluid and low-density lipoprotein receptor is found in the brain suggests that the brain may have an active lipid transport system. In plasma, cholesteryl ester transfer protein mediates the exchange and net transfer of cholesteryl ester and triglycerides among lipoproteins.
Gertrud Wolfbauer +2 more
exaly +3 more sources
Future of Cholesteryl Ester Transfer Protein Inhibitors
Annual Review of Medicine, 2014The cholesteryl ester transfer protein (CETP) plays an integral role in the metabolism of plasma lipoproteins. Despite two failures, CETP inhibitors are still in clinical development. We review the genetics of CETP and coronary disease, preclinical data on CETP inhibition and atherosclerosis, and the effects of CETP inhibition on cholesterol efflux ...
Daniel J, Rader, Emil M, deGoma
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Cholesteryl ester transfer protein and its inhibition
Cellular and Molecular Life Sciences, 2010Cholesteryl ester transfer protein (CETP) is a plasma glycoprotein that facilitates the transfer of cholesteryl esters from the atheroprotective high density lipoprotein (HDL) to the proatherogenic low density lipoprotein cholesterol (LDL) and very low density lipoprotein cholesterol (VLDL) leading to lower levels of HDL but raising the levels of ...
Olaf, Weber +3 more
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Cholesteryl Ester Transfer Protein (CETP) Inhibitors
Current Topics in Medicinal Chemistry, 2009Epidemiological studies have demonstrated an inverse correlation between plasma concentrations of high-density lipoprotein cholesterol (HDL-C) and incidence of coronary heart disease (CHD); thus new therapies for raising HDL-C levels have been the focus of significant efforts by the cardiovascular medicine community.
Julianne A, Hunt, Zhijian, Lu
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