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Determination of cholic acid is very important and necessary in body fluids due to its both pharmaceutical and clinical significance. In this study, a quartz crystal microbalance (QCM) nanosensor, which is imprinted cholic acid, has been developed for ...
Aytaç Gültekin +2 more
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Bacterial oxidation of cholic acid
Archives of Biochemistry and Biophysics, 1954Abstract 1. 1. Ammonium cholate (0.1%) on perfusion through soil yields a substance in the soil perfusate with λ max at 246 mμ in water. This substance is referred to as X246. 2. 2. The organisms responsible for the conversion of cholic acid to X246 have been isolated and are provisionally identified as Nocardia . 3. 3.
A H, HALPERIN +2 more
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Microbiological Degradation of Cholic Acid
Nature, 1957FOR the microbiological oxidation of cholic acid, two possible pathways different from that found in A. faecalis1 or E. coli2 can be suggested.
S, HAYAKAWA +3 more
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New cholic acid derivatives: Biocatalytic synthesis and molecular docking study [PDF]
A series of cholic acid derivatives was synthesized by enzyme catalysis. Eleven acetyl and ester derivatives of cholic acid, eight of them new compounds, were obtained through regioselective lipase-catalyzed reactions in very good to excellent yield. The
Guadalupe Garcia Linares +1 more
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Anodic electrochemical oxidation of cholic acid
Steroids, 2001Regioselectivity in the anodic electrochemical oxidation of cholic acid with different anodes is described. The oxidation with PbO(2) anode affords the dehydrocholic acid in quantitative yield after 22 h. 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholan-24-oic acid (59%) and 3alpha-hydroxy-7,12-dioxo-5beta-cholan-24-oic acid (51%) are obtained stopping the ...
Medici A. +5 more
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Synthesis of the specific monosulfates of cholic acid
Steroids, 1975The three isomeric cholic acid-monosulfates were synthetized and characterized. Cholic acid-3-sulfate was obtained by reacting cholic acid for 2 min with chlorosulfonic acid in pyridine and chromatography of the resulting bile salt mixture on Sephadex LH-20.
G, Parmentier, H, Eyssen
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Radioimmunoassay of serum conjugated cholic acid
Clinica Chimica Acta, 1976A radioimmunoassay for serum conjugated cholic acid is described using antiserum obtained five weeks after immunization of rabbits with cholic acid bovine serum albumin conjugate. Prior to the radioimmunoassay, extraction of bile acids was performed with Amberlite XAD-2. The displacement curve of glyco[3H]cholic acid was linear on a logit-log plot from
S, Matern, R, Krieger, W, Gerok
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Synthesis of biological precursors of cholic acid
Steroids, 1978This paper describes a new and convenient procedure for the synthesis of 5beta-cholestane-3alpha,7alpha,12alpha,24-tetrol (24R and 24 S) and 5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol starting from 5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol.
B, Dayal +4 more
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Transformation of cholic acid by Arthrobacter simplex
Steroids, 1993Fermentation of cholic acid with Arthrobacter simplex (IICB 227) under aerobic conditions yielded 3,12-dioxo-23,24-dinorchola-4,6-dienoic acid, 7 alpha-hydroxy-3,12-dioxo-23,24-dinorchol-4-enoic acid, 3 alpha, 7 alpha-dihydroxy-12-oxo-5 beta-cholan-24-oic acid, 3 alpha, 7 alpha-dihydroxy-12-oxo-5 beta-23,24-dinorcholan-22-oic acid, 7 alpha, 12 alpha ...
E, Mukherjee, S, Banerjee, S B, Mahato
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Global optimization of cholic acid aggregates
The Journal of Chemical Physics, 2014In spite of recent investigations into the potential pharmaceutical importance of bile acids as drug carriers, the structure of bile acid aggregates is largely unknown. Here, we used global optimization techniques to find the lowest energy configurations for clusters composed between 2 and 10 cholate molecules, and evaluated the relative stabilities of
Balázs, Jójárt +3 more
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