Results 181 to 190 of about 5,133,102 (254)

Bacterial oxidation of cholic acid

Archives of Biochemistry and Biophysics, 1954
Abstract 1. 1. Ammonium cholate (0.1%) on perfusion through soil yields a substance in the soil perfusate with λ max at 246 mμ in water. This substance is referred to as X246. 2. 2. The organisms responsible for the conversion of cholic acid to X246 have been isolated and are provisionally identified as Nocardia . 3. 3.
A H, HALPERIN, J H, QUASTEL, P G, SCHOLEFIELD   +2 more
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Cholic acid derivatives: novel antimicrobials

Expert Opinion on Investigational Drugs, 2000
Mimics of squalamine and polymyxin B (PMB) have been prepared from cholic acid in hope of finding new antimicrobial agents. The squalamine mimics include the polyamine and sulphate functionalities found in the parent antibiotic, however, the positions relative to the steroid nucleus have been exchanged.
P B, Savage, C, Li
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Microbiological Degradation of Cholic Acid

Nature, 1957
FOR the microbiological oxidation of cholic acid, two possible pathways different from that found in A. faecalis1 or E. coli2 can be suggested.
S, HAYAKAWA, T, FUJII, Y, SABURI, T, EGUCHI   +3 more
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Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1

Biological chemistry, 2018
The human cytochrome P450 enzyme CYP8B1 is a crucial regulator of the balance of cholic acid (CA) and chenodeoxycholic acid (CDCA) in the liver. It was previously shown to catalyze the conversion of 7α-hydroxycholest-4-en-3-one, a CDCA precursor, to 7α ...
Linbing Fan, J. Joseph, P. Durairaj, M. Parr, M. Bureik   +4 more
semanticscholar   +1 more source

Radioimmunoassay of serum conjugated cholic acid

Clinica Chimica Acta, 1976
A radioimmunoassay for serum conjugated cholic acid is described using antiserum obtained five weeks after immunization of rabbits with cholic acid bovine serum albumin conjugate. Prior to the radioimmunoassay, extraction of bile acids was performed with Amberlite XAD-2. The displacement curve of glyco[3H]cholic acid was linear on a logit-log plot from
S, Matern, R, Krieger, W, Gerok
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Anodic electrochemical oxidation of cholic acid

Steroids, 2001
Regioselectivity in the anodic electrochemical oxidation of cholic acid with different anodes is described. The oxidation with PbO(2) anode affords the dehydrocholic acid in quantitative yield after 22 h. 3alpha,12alpha-Dihydroxy-7-oxo-5beta-cholan-24-oic acid (59%) and 3alpha-hydroxy-7,12-dioxo-5beta-cholan-24-oic acid (51%) are obtained stopping the ...
Medici A., Pedrini P., De Battisti A., Fantin G., Fogagnolo M., Guerrini A.   +5 more
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Global optimization of cholic acid aggregates

The Journal of Chemical Physics, 2014
In spite of recent investigations into the potential pharmaceutical importance of bile acids as drug carriers, the structure of bile acid aggregates is largely unknown. Here, we used global optimization techniques to find the lowest energy configurations for clusters composed between 2 and 10 cholate molecules, and evaluated the relative stabilities of
Balázs, Jójárt, Béla, Viskolcz, Mihalj, Poša, Szilard N, Fejer   +3 more
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Anionic Facial Amphiphiles from Cholic Acid

Organic Letters, 2000
[structure:see text] Anionic facial amphiphiles have been prepared from cholic acid. These compounds offer antipodes of recently reported cationic amphiphiles derived from cholic acid. The synthesis of the anionic amphiphiles was accomplished in few steps from a common intermediate.
U, Taotafa, D B, McMullin, S C, Lee, L D, Hansen, P B, Savage   +4 more
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Selective inclusion by cholic acid

Journal of the Chemical Society, Chemical Communications, 1993
Crystallographic, thermodynamic and molecular mechanics results show that cholic acid enclathrates nitrobenzene in preference to aniline.
Mino R. Caira, Luigi R. Nassimbeni, Janet L. Scott   +2 more
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Effect of coinfusion of cholic acid and sulfated cholic acid on bile formation in rats

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
The effect of combined infusion of sulfated cholic acid and nonsulfated cholic acid on bile formation was investigated. The data show that the secretion of sulfated cholic acid is slower and does not share the same transport mechanism(s) as nonsulfated cholic acid.
I M, Yousef, B, Tuchweber, D, Mignault, A, Weber   +3 more
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