Results 111 to 120 of about 263,913 (277)

Controlling the Decoration of the Reduced Graphene Oxide Surface with Pyrene-Functionalized Gold Nanoparticles [PDF]

, 2017
We exploited a non‐covalent approach based on π‐stacking interactions to address the formation of hybrids between pyrene‐functionalized gold nanoparticles (PyAuNPs) and reduced graphene oxide (RGO), in which the former are distributed homogeneously on
Abdolhosseinzadeh, Balandin, Brunetti, Canesi, Daniel, Elghanian, Ferrari, Glaeske, Holmlin, Ismaili, Jasuja, Katz, Lee, Li, Liu, Lu, Manea, Modugno, Nair, Novoselov, Park, Perez, Perrone, Qiu, Rani, Rodrigo, Sahoo, Salice, Setaro, Su, Vilian, Wang, Wick, Xia, Yeh, Yin, Zhang, Zhao, Zhao, Zhao, Zoladek   +40 more
core   +2 more sources

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

CHML regulates migration and invasion in hepatocellular carcinoma via transcriptional and metabolic reprogramming

Frontiers in Oncology
BackgroundHepatocellular carcinoma (HCC), a prevalent malignant neoplasm, presents significant therapeutic challenges. However, the key factors and mechanisms driving HCC metastasis remain incompletely understood.
Huanqian Cao, Siyu Wang, Li Zhang, Li Zhang, Heying Xie, Yiqiong Liu, Ruijiao Kong, Yin Jia, Ling Lu, Junfeng Jiang, Junfeng Jiang, Shanrong Liu   +11 more
doaj   +1 more source

NMR studies of membrane structure and dynamics [PDF]

, 1978
Over the past decade, there has been considerable interest in the motional state of the phospholipid bilayer membrane. The motivation underlying these efforts has been the contention that the phospholipid bilayer is the basic matrix in which membrane ...
Bocian, David F., Chan, Sunney I.
core   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Hydrogen bonding as a clustering agent in protic ionic liquids: like-charge vs opposite-charge dimer formation [PDF]

, 2018
The local structure of a series of homologous protic ionic liquids (PILs) is investigated using ab initio computations and ab initio-based molecular dynamics. The purpose of this work is to show that in PILs the network of hydrogen bonds may promote like-
Adenusi, Henry, Bodo, Enrico, Le Donne, Andrea, Porcelli, Francesco   +3 more
core   +3 more sources

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Xylem surfactants introduce a new element to the cohesion-tension theory [PDF]

, 2016
Vascular plants transport water under negative pressure without constantly creating gas bubbles that would disable their hydraulic systems. Attempts to replicate this feat in artificial systems almost invariably result in bubble formation, except under ...
Do, Aissa YT, Espino, Susana, Jansen, Steven, Michaud, Joseph M, Nima, Neda, Papahadjopoulos-Sternberg, Brigitte, Romo, David M, Schenk, H Jochen, Steppe, Kathy, Yang, Jinlong, Zuo, Yi Y   +10 more
core   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source