Results 91 to 100 of about 183,519 (291)
One-Carbon Metabolism Nutrients, Genetic Variation, and Diabetes Mellitus [PDF]
Diabetes & Metabolism JournalDiabetes mellitus (DM) affects about 9.3% of the population globally. Hyperhomocysteinemia (HHcy) has been implicated in the pathogenesis of DM, owing to its promotion of oxidative stress, β-cell dysfunction, and insulin resistance.
Jie Zhu +4 more
doaj +1 more source
, 2019 Betaine is a trimethylglycine, serves as osmoregulator to prevent dehydration and plasmolysis under adverse hyperosmotic environments. Choline oxidase gene from Arthrobacter sp.
Prashant Gaur +5 more
core +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Eggs – a scoping review for Nordic Nutrition Recommendations 2023
Food & Nutrition ResearchCardiovascular diseases (CVD), type 2 diabetes (T2D), and cancer are a significant public health burden in the Nordic and Baltic countries. High intake of eggs, mainly due to its high cholesterol content, has been suggested to have adverse health effects.
Jyrki K. Virtanen, Susanna C. Larsson
doaj +1 more source
, 2012 A 10-week feeding trial was conducted in a flow-through system to determine dietary choline requirement for juvenile gibel carp (Carassius auratus gibelio) (5.5 +/- 0.1 g).
Yang, Y. +5 more
core +1 more source
, 2021 Acknowledgments We gratefully acknowledge A.J.H. Spiering for synthetic support. The authors acknowledge the financial support from the Dutch Ministry of Education, Culture and Science (Gravity program 024.001.035), the ERC Advanced Grant (SYNMAT─788618)
Vleugels, Merle +7 more
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Advanced Science, EarlyView.This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen +11 more
wiley +1 more source
Effects of choline ingestion on endurance performance
, 1988 Plasma choline levels have been reported to be significantly reduced in athletes at the endof prolonged, exhaustive exercise (marathon running), and this may affect the release of acetylcholine at the neuromuscular junction (16).
Burns, Jennifer M.
core
Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress
Advanced Science, EarlyView.Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen +11 more
wiley +1 more source