Results 91 to 100 of about 187,609 (208)

Incorporation of choline into Streptococcus pneumoniae cell wall antigens:Evidence for choline kinase activity

open access: yes, 1996
The choline-containing teichoic and lipoteichoic acids play an important part in cell wall metabolism of Streptococcus pneumoniae. We propose that a choline kinase enzyme has a role in the synthesis of these antigens.
Gillespie, Stephen H.   +2 more
core   +1 more source

Breast cancer aggressiveness, miRNA and choline [PDF]

open access: yes, 2020
The level of choline kinase in human breast cancer cells was found to be overexpress as compared to normal human mammary epithelial cells. This book presents a study that we investigated the potential expression of choline in 18F-FCH PET/CT as compared ...
Shaharuddin, Shazreen   +2 more
core  

On the Catalytic Mechanism of Choline Oxidase

open access: yes, 2016
Choline oxidase catalyzes the four-electron oxidation of choline to glycine betaine, with betaine aldehyde as an intermediate. In this study, primary deuterium and solvent kinetic isotope effects have been used to elucidate the mechanism for substrate ...
Giovanni Gadda (450751), Fan (3209073)
core   +1 more source

The choline-acetylcholine cycle.

open access: yes, 2017
The enzyme choline acetyltransferase builds acetylcholine (ACH) from choline (CHO) and acetyl-CoA. After ACH is released in the synaptic cleft, the enzyme acetylcholinesterase converts ACH into the inactive metabolites CHO and acetate.
Paul Gerald Mullins (3743626)   +4 more
core   +1 more source

Choline nutrition, choline status, and developmental outcome in early childhood

open access: yes, 2014
Choline is an essential dietary nutrient that plays a key role as one of the few sources of methyl donors in the diet. Additional roles include the neurotransmitter acetylcholine and lipids such as phosphatidylcholine and sphingomyelin. Studies in adults
Wu, Brian Tid-Fung
core   +1 more source

Choline as a Modulator of Periparturient Diseases in Dairy Cows

open access: yesVeterinary Sciences
Dairy cows experiencing negative energy balance (NEB) are prone to metabolic and inflammatory disorders, including ketosis, fatty liver, mastitis, endometritis, and hypocalcemia, which impair productive and reproductive performance.
Fenghong Wang   +3 more
doaj   +1 more source

Nutrition and DNA Methylation: How Dietary Methyl Donors Affect Reproduction and Aging

open access: yesDietetics
Methylation is a biochemical process involving the addition of methyl groups to proteins, lipids, and nucleic acids (both DNA and RNA). DNA methylation predominantly occurs on cytosine and adenine nucleobases, and the resulting products—most frequently 5-
Fanny Cecília Dusa   +2 more
doaj   +1 more source

Combined Bacopa, Phosphatidylserine, and Choline Protect Against Stress-Induced Neurotoxicity

open access: yesBiomedicines
Background/Objectives: Chronic stress leads to sustained elevations in cortisol levels, which promote neuronal damage and impair memory. Prolonged stress also enhances proinflammatory signaling.
Chiara Sasia   +2 more
doaj   +1 more source

Inhibition of Choline Transport into Human Erythrocytes by Choline Mustard Aziridinium Ion

open access: yes, 1975
Acetylcholine mustard aziridinium ion inhibited the transport of [3H]choline into human erythrocytes. Treatment of the erythrocytes with 1 × 10−4 M tetraethylpyrophosphate prevented the inhibition of [3H]choline transport by acetylcholine mustard ...
E. Howard Colhoun, John G. Clement
core   +1 more source

Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke

open access: yes, 2013
CDP-choline has shown neuroprotective effects in cerebral ischemia. In humans, although a recent trial International Citicoline Trial on Acute Stroke (ICTUS) has shown that global recovery is similar in CDP-choline and placebo groups, CDP-choline was ...
Camarero, Guadalupe   +9 more
core   +1 more source

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