Results 71 to 80 of about 183,519 (291)

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

Nano-Windmill Inhibits Macrophage Activation Via Choline Uptake Reduction

open access: yesInternational Dental Journal
Aim or purpose: This study aims to investigate the anti-inflammatory effects of a novel tetrahedral framework nucleic acid (tFNA)-based siRNA delivery system, named “nano-windmill,” which targets slc44a1 to inhibit macrophage activation by reducing ...
Nanxin Liu, Zhong Yuke, Pang Xiaoxiao
doaj   +1 more source

Effects of Rumen-Protected Choline on Growth Performance, Carcass Characteristics and Blood Lipid Metabolites of Feedlot Lambs

open access: yesAnimals, 2020
Choline is an essential nutrient for animals, but dietary choline is degraded in the rumen, and thus, should be offered as rumen-protected choline (RPC) in ruminants.
Jorge R. Kawas   +3 more
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

open access: yesAdvanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang   +11 more
wiley   +1 more source

Magnetic resonance spectroscopy in the evaluation of treatment efficacy in unipolar major depressive disorder: a review of the literature [PDF]

open access: yes, 2012
More and more neuroimaging studies are using in vivo proton magnetic resonance spectroscopy (1H-MRS) to explore correlates of response to therapy in major depressive disorder (MDD). Their aim is to further understanding of the effects of neurotransmitter
Barale, Francesco   +10 more
core   +1 more source

Choline loss during hemodialysis: Homeostatic control of plasma choline concentrations [PDF]

open access: yes, 1976
Choline loss during hemodialysis: Homeostatic control of plasma choline concentrations. Endogenous concentrations of free choline in plasma were measured in azotemic subjects receiving repetitive hemodialysis and excretion of free choline into the ...
Acara, Margaret   +3 more
core   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

High‐Performance Bio‐Glue From the Berries of a Parasitic Plant

open access: yesAdvanced Materials, EarlyView.
We report a fully bio‐based adhesive derived primarily from a (poly)saccharide extract obtained from the berries of the hemi‐parasitic plant mistletoe (Viscum album), supplemented with tannic and malic acid without any further chemical functionalization.
Ufuk Gürer   +8 more
wiley   +1 more source

Current Staging Procedures in Urinary Bladder Cancer

open access: yesDiagnostics, 2013
Currently computed tomography (CT) represents the most widely used standard imaging modality in muscle-invasive urinary bladder cancer. Visualization of local tumor or depth of invasion as well as lymph node staging, however, is often impaired.
Ambros J. Beer   +5 more
doaj   +1 more source

Efficient Sunlight Degradation of Wide‐Spectrum Antibiotics Through Enhanced Charge Separation in SnTCPP NPs‐Nb2C Schottky Heterojunction: Ultrafast Carrier Dynamic Study

open access: yesAdvanced Materials Interfaces, EarlyView.
Due to enhanced charge transfer and carrier mobility on the surface, the SnTCPP NPs‐Nb2C Schottky heterojunctions demonstrate exceptional sunlight‐driven catalytic activity toward tetracycline antibiotics and ofloxacin degradation, achieving a removal efficiency of up to 99.9% within 60 min of irradiation, both in model wastewater and natural water ...
Juanxuan Guo   +5 more
wiley   +1 more source

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