Results 61 to 70 of about 168,661 (305)

Ensemble Learning for Breast Cancer Lesion Classification: A Pilot Validation Using Correlated Spectroscopic Imaging and Diffusion-Weighted Imaging

Metabolites, 2023
The main objective of this work was to evaluate the application of individual and ensemble machine learning models to classify malignant and benign breast masses using features from two-dimensional (2D) correlated spectroscopy spectra extracted from five-
Ajin Joy, Marlene Lin, Melissa Joines, Andres Saucedo, Stephanie Lee-Felker, Jennifer Baker, Aichi Chien, Uzay Emir, Paul M. Macey, M. Albert Thomas   +9 more
doaj   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Nano-Windmill Inhibits Macrophage Activation Via Choline Uptake Reduction

International Dental Journal
Aim or purpose: This study aims to investigate the anti-inflammatory effects of a novel tetrahedral framework nucleic acid (tFNA)-based siRNA delivery system, named “nano-windmill,” which targets slc44a1 to inhibit macrophage activation by reducing ...
Nanxin Liu, Zhong Yuke, Pang Xiaoxiao
doaj   +1 more source

Effects of Rumen-Protected Choline on Growth Performance, Carcass Characteristics and Blood Lipid Metabolites of Feedlot Lambs

Animals, 2020
Choline is an essential nutrient for animals, but dietary choline is degraded in the rumen, and thus, should be offered as rumen-protected choline (RPC) in ruminants.
Jorge R. Kawas, Jose F. Garcia-Mazcorro, Hector Fimbres-Durazo, Maria E. Ortega-Cerrilla   +3 more
doaj   +1 more source

Arthrobacter Strains from Industrial Polluted Soil and its Oxidative Potential of Choline Oxidase Gene

, 2019
Betaine is a trimethylglycine, serves as osmoregulator to prevent dehydration and plasmolysis under adverse hyperosmotic environments. Choline oxidase gene from Arthrobacter sp.
Prashant Gaur, Sujan Ganapathy P.S., Sonia Gaur, Arjun H.M., Lokesha S., Ravi Kumar Y.S.   +5 more
core   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Effects of Choline on DNA Methylation and Macronutrient Metabolic Gene Expression in In Vitro Models of Hyperglycemia

, 2016
Choline is an essential nutrient that plays an important role in lipid metabolism and DNA methylation. Studies in rodents suggest that choline may adversely affect glycemic control, yet studies in humans are lacking. Using the human hepatic and placental
Jack-Roberts, Chauntelle, Xinyin Jiang, Chauntelle Jack-Roberts, Esther Greenwald, Jiang, Xinyin, Greenwald, Esther   +5 more
core   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Dietary choline requirement in slight methionine-deficient diet for juvenile gibel carp (Carassius auratus gibelio)

, 2012
A 10-week feeding trial was conducted in a flow-through system to determine dietary choline requirement for juvenile gibel carp (Carassius auratus gibelio) (5.5 +/- 0.1 g).
Yang, Y., Duan, Y., Xie, S., Xie, S (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China., Han, D., Zhu, X.   +5 more
core   +1 more source

Data_Sheet_1_Saccharomyces Boulardii Ameliorates Non-alcoholic Steatohepatitis in Mice Induced by a Methionine-Choline-Deficient Diet Through Gut-Liver Axis.docx

, 2022
Non-alcoholic steatohepatitis (NASH) is affecting people worldwide. Changes in the intestinal microbiome are crucial to NASH. A previous study showed that eradicating intestinal fungi ameliorates NASH; however, the role of intestinal fungi in the ...
An-Ming Yang (12436298), Ming-Chih Hou (383484), Kuei-Chuan Lee (383486), Guan-Da Syu (206409), Shih-Hao Liu (9772121), Hao-Jhe Sun (585932), Chien-Yu Lin (50716), Han-Chieh Lin (115193)   +7 more
core   +1 more source