Results 41 to 50 of about 139,290 (260)

Trimethylamine N-Oxide as a Potential Biomarker for Cardiovascular Disease: Its Association with Dietary Sources of Trimethylamine N-Oxide and Microbiota

Eurasian Journal of Medicine, 2023
Trimethylamine N-oxide (TMAO), the oxidized form of trimethylamine (TMA), was previously thought to be a waste product but is now considered an important risk factor for cardiovascular disease (CVD) and its comorbidities. Foods or supplements containing
Yasemin Karaagac
doaj   +1 more source

Tannic Acid‐Modified Cellulose Nanofiber Reinforced Polymerizable Eutectogels for High‐Performance Stretchable Strain Sensors

Advanced Functional Materials, EarlyView.
A polymerizable deep eutectic solvent is reinforced with tannic acid‐modified cellulose nanofibers to construct a hierarchical dynamic eutectogel network. Synergistic covalent and reversible interactions impart ultrahigh stretchability, high ionic conductivity, broad temperature tolerance, self‐healing, and strong adhesion, enabling robust wearable ...
Huang Wu, Yang Hu, Youmin Tuo, Weide Zhang, Nanzhu Bao, Haitao Wu, Zhuangzhuang Chu, Yunhua Chen, Tao Wang, Teng Yuan, Hongbo Zeng, Zhuohong Yang   +11 more
wiley   +1 more source

Machine learning-based early screening of mild cognitive impairment using nutrition-related biomarkers and functional indicators

Frontiers in Aging Neuroscience
ObjectivesMild cognitive impairment (MCI), an early stage of cognitive decline preceding dementia, poses a growing public health concern, especially in aging populations.
Ling Yuan, Yao Zhang, Yiwen Wu, Anke Zhang, He Bai, Mengyao He, Zhaoxin Wang, Liqiang Zheng, Liqiang Zheng, Liqiang Zheng   +9 more
doaj   +1 more source

Enzyme‐Loaded Fe3+‐Modified Polydopamine Microparticles: Bioreactor Systems for Operating Biocatalytic Cascades, Enantioselective Transformations and Sensor Applications

Advanced Functional Materials, EarlyView.
Enzyme‐loaded Fe3+‐modified polydopamine microparticles (Fe3+‐PD) act as hybrid biocatalytic frameworks demonstrating NADH peroxidase‐mimic catalytic activities, operation of biocatalytic cascades in confined media, and enantioselective oxidation of D/L‐DOPA. ABSTRACT We report on the synthesis of Fe3+‐modified porous polydopamine microparticles acting
Liubing Kong, Sérgio R. S. Veloso, Yichen Han, Jianghe Zhao, Vitaly Gutkin, Ofir Tirosh, Itamar Willner   +6 more
wiley   +1 more source

Nano-Windmill Inhibits Macrophage Activation Via Choline Uptake Reduction

International Dental Journal
Aim or purpose: This study aims to investigate the anti-inflammatory effects of a novel tetrahedral framework nucleic acid (tFNA)-based siRNA delivery system, named “nano-windmill,” which targets slc44a1 to inhibit macrophage activation by reducing ...
Nanxin Liu, Zhong Yuke, Pang Xiaoxiao
doaj   +1 more source

Effects of Rumen-Protected Choline on Growth Performance, Carcass Characteristics and Blood Lipid Metabolites of Feedlot Lambs

Animals, 2020
Choline is an essential nutrient for animals, but dietary choline is degraded in the rumen, and thus, should be offered as rumen-protected choline (RPC) in ruminants.
Jorge R. Kawas, Jose F. Garcia-Mazcorro, Hector Fimbres-Durazo, Maria E. Ortega-Cerrilla   +3 more
doaj   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

QUANTIFICATION OF TOTAL DIETARY CHOLINE CONTENT IN FOODS AFTER HYDROLYSIS WITH PHOSPHOLIPASE D IN COMPARISON WITH ACID HYDROLYSIS [PDF]

Journal of Food and Dairy Sciences, 2015
A previously we have developed a method for choline quantification that have been based on acid hydrolysis. In this study, a simple hydrolysis procedure for phospholipids in foods using only phospholipase D (PLD) was developed.
Michael Lever, Christopher McEntyre, Sandy Slow, M. Hefni   +3 more
doaj   +1 more source

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis

Advanced Materials, EarlyView.
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena, Lucia Suarez, Aitor Ontoria, Francisca J. Benitez, Elixabete Rezabal, María Soledad Orellano, Marcelo Calderón, Cristián Huck‐Iriart, Agustin S. Picco, Matias L. Picchio, Ana Beloqui   +10 more
wiley   +1 more source