Results 41 to 50 of about 183,519 (291)

Choline Redistribution during Adaptation to Choline Deprivation [PDF]

Journal of Biological Chemistry, 2007
Choline is an important nutrient for mammals. Choline can also be generated by the catabolism of phosphatidylcholine synthesized in the liver by the methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Complete choline deprivation is achieved by feeding Pemt(-)(/)(-) mice a choline-deficient diet and is lethal
Zhaoyu, Li, Luis B, Agellon, Dennis E, Vance   +2 more
openaire   +2 more sources

Breast cancer aggressiveness, miRNA and choline [PDF]

, 2020
The level of choline kinase in human breast cancer cells was found to be overexpress as compared to normal human mammary epithelial cells. This book presents a study that we investigated the potential expression of choline in 18F-FCH PET/CT as compared ...
Shaharuddin, Shazreen, Ahmad Saad, Fathinul Fikri, Osman, Muhamed T.   +2 more
core   +1 more source

The Phospholipid N-Methyltransferase and Phosphatidylcholine Synthase Pathways and the ChoXWV Choline Uptake System Involved in Phosphatidylcholine Synthesis Are Widely Conserved in Most, but Not All Brucella Species

Frontiers in Microbiology, 2021
The brucellae are facultative intracellular bacteria with a cell envelope rich in phosphatidylcholine (PC). PC is abundant in eukaryotes but rare in prokaryotes, and it has been proposed that Brucella uses PC to mimic eukaryotic-like features and avoid ...
Beatriz Aragón-Aranda, Leyre Palacios-Chaves, Miriam Salvador-Bescós, María Jesús de Miguel, María Jesús de Miguel, Pilar M. Muñoz, Pilar M. Muñoz, Miguel Ángel Vences-Guzmán, Amaia Zúñiga-Ripa, Leticia Lázaro-Antón, Christian Sohlenkamp, Ignacio Moriyón, Maite Iriarte, Raquel Conde-Álvarez   +13 more
doaj   +1 more source

Choline-containing metabolite amplitude changes in synthetic data.

, 2017
Amplitudes of choline (CHO, red) and the combined phosphocholine/glycerophosphocholine peak (PHC/GPC, blue) estimated using the MOD_CHOsep (top) and MOD_CHOglobal (bottom) models in synthetic data. Estimated levels of CHO (red) and PHC/GPC (blue) show an
Paul Gerald Mullins (3743626), Somya Iqbal (3743635), Tiffany Bell (3743632), Anastasia Christakou (3743629), Michael Lindner (383308)   +4 more
core   +1 more source

Synthesis, isolation and purification of [11C]-choline [PDF]

, 2016
[11C]-choline is an effective PET tracer used for imaging of neoplastic lesions and metastases of the prostate cancer. However, its production can be a challenge for manufacturers, as it has not yet been described in Polish or European pharmacopoeia.
Michał Jadwiński, Marcin Szydło, Kamil Gorczewski, Agnieszka Chmura, Maria Sokół   +4 more
core   +1 more source

Too much of a good thing? Lecithin and mental health

World Nutrition, 2019
The present article is concerned with some aspects of lecithin metabolism and function as they pertain to mental health. Given that lecithin is a popular emulsifier in the food industry, as well as an active substance in many supplement formulations ...
Ioannis Tsoukalas
doaj   +1 more source

Elusive physiological role of prostatic acid phosphatase (PAP): generation of choline for sperm motility via auto-and paracrine cholinergic signaling

Frontiers in Physiology, 2023
Prostatic acid phosphatase (PAP) exists as two splice variants, secreted PAP and transmembrane PAP, the latter of which is implicated in antinociceptive signaling in dorsal root ganglia.
Peter J. Hanley
doaj   +1 more source

Optimisation of acid hydrolysis conditions of choline esters and mass spectrometric determination of total choline in various foods

Scientific Reports
Determining the content of the nutrient choline in foods and obtaining the required amount from the diet are crucial. One way to measure choline in foods is by converting choline esters to free choline via acid hydrolysis, followed by quantifying the ...
Yoshinari Hirakawa, Kazuhiro Fujita, Masako Katayama, Toshiaki Yokozeki, Yushi Takahashi, Izumi Yoshida, Kiyotaka Nakagawa   +6 more
doaj   +1 more source

Gut Microbiota Targeted Approach in the Management of Chronic Liver Diseases

Frontiers in Cellular and Infection Microbiology, 2022
The liver is directly connected to the intestines through the portal vein, which enables the gut microbiota and gut-derived products to influence liver health.
Jing Liu, Dakai Yang, Xiaojing Wang, Paul Tetteh Asare, Qingwen Zhang, Lixin Na, Lei Shao   +6 more
doaj   +1 more source

Total choline and choline-containing moieties of commercially available pulses

, 2014
Estimating dietary choline intake can be challenging due to missing foods in the current United States Department of Agriculture (USDA) database. The objectives of the study were to quantify the choline-containing moieties and the total choline content ...
Jacobs, René L., Field, Catherine J., Kosik, Sarah J., Curtis, Jonathan M., Lewis, Erin D., Zhao, Yuan-Yuan   +5 more
core   +1 more source