Results 21 to 30 of about 183,519 (291)

Integrating Choline and Specific Intestinal Microbiota to Classify Type 2 Diabetes in Adults: A Machine Learning Based Metagenomics Study

open access: yesFrontiers in Endocrinology, 2022
Emerging evidence is examining the precise role of intestinal microbiota in the pathogenesis of type 2 diabetes. The aim of this study was to investigate the association of intestinal microbiota and microbiota-generated metabolites with glucose ...
Qiang Zeng   +25 more
doaj   +1 more source

Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei : the ethanolamine and choline kinases [PDF]

open access: yes, 2008
Note related output below contains correction of this paper.Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (glycero-phosphoethanolamine) and GPCho (glycerophosphocholine).
Smith, Terry K.   +6 more
core   +1 more source

11C-Choline positive but 18F-FDG negative pancreatic metastasis from renal cell carcinoma on PET [PDF]

open access: yes, 2017
2017-05Choline is a new PET tracer, which uptake may occur via a choline-specific transporter protein and be accelerated during the proliferation of tumor cells.
Nakasho, Keiji   +18 more
core   +1 more source

The Diagnostic Role of 18F-Choline, 18F-Fluciclovine and 18F-PSMA PET/CT in the Detection of Prostate Cancer With Biochemical Recurrence: A Meta-Analysis

open access: yesFrontiers in Oncology, 2021
BackgroundDiagnosing the biochemical recurrence (BCR) of prostate cancer (PCa) is a clinical challenge, and early detection of BCR can help patients receive optimal treatment. We conducted a meta-analysis to define the diagnostic accuracy of PET/CT using
Rang Wang   +3 more
doaj   +1 more source

Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. III. Choline transport and uptake by simple diffusion and lack of direct exchange with phosphatidylcholine

open access: yesJournal of Lipid Research, 1971
The initial rate of incorporation of methyl-labeled choline into the acid-soluble pool (phosphorylcholine) of Novikoff hepatoma cells growing in suspension culture was investigated as a function of the choline concentration in the medium.
PETER G.W. PLAGEMAEN
doaj   +1 more source

In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism

open access: yesViruses, 2020
Choline is an essential nutrient required for normal neuronal and muscular development, as well as homeostatic regulation of hepatic metabolism. In the liver, choline is incorporated into the main eukaryotic phospholipid, phosphatidylcholine (PC), and ...
Kaelan Gobeil Odai   +13 more
doaj   +1 more source

Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds

open access: yesFrontiers in Molecular Biosciences, 2022
Osmolytes are naturally occurring small molecular weight organic molecules, which are accumulated in large amounts in all life forms to maintain the stability of cellular proteins and hence preserve their functions during adverse environmental conditions.
Ashal Ilyas   +10 more
doaj   +1 more source

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. [PDF]

open access: yes, 2013
BACKGROUND: Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In humans, altered DNA methylation patterns have
Dominguez Salas, Paula   +34 more
core   +1 more source

Biosynthesis of phosphatidyl choline during prenatal development of the rat lung

open access: yesJournal of Lipid Research, 1968
The biosynthesis of phosphatidyl choline in rat lung during prenatal development is of interest in connection with the mechanisms of functional development of the lung, particularly in relation to the production of lung surfactant and the control of ...
Paul A. Weinhold
doaj   +1 more source

NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy

open access: yesPlants, 2022
Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng   +5 more
doaj   +1 more source

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