Results 21 to 30 of about 187,609 (208)

In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism

Viruses, 2020
Choline is an essential nutrient required for normal neuronal and muscular development, as well as homeostatic regulation of hepatic metabolism. In the liver, choline is incorporated into the main eukaryotic phospholipid, phosphatidylcholine (PC), and ...
Kaelan Gobeil Odai, Conor O’Dwyer, Rineke Steenbergen, Tyler A. Shaw, Tyler M. Renner, Peyman Ghorbani, Mojgan Rezaaifar, Shauna Han, Marc-André Langlois, Angela M. Crawley, Rodney S. Russell, John P. Pezacki, D. Lorne Tyrrell, Morgan D. Fullerton   +13 more
doaj   +1 more source

Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds

Frontiers in Molecular Biosciences, 2022
Osmolytes are naturally occurring small molecular weight organic molecules, which are accumulated in large amounts in all life forms to maintain the stability of cellular proteins and hence preserve their functions during adverse environmental conditions.
Ashal Ilyas, Yasanandana Supunsiri Wijayasinghe, Ilyas Khan, Nourhan M. El Samaloty, Mohd Adnan, Tanveer Ali Dar, Nitesh Kumar Poddar, Laishram R. Singh, Hemlata Sharma, Shahanavaj Khan, Shahanavaj Khan   +10 more
doaj   +1 more source

NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy

Plants, 2022
Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng, Gerhard Prinsloo, Hintsa T. Araya, Stephen O. Amoo, Christian P. du Plooy, Phatu W. Mashela   +5 more
doaj   +1 more source

Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay

Scientific Reports, 2018
Blood choline has been proposed as a predictor of acute coronary syndrome (ACS), however different testing procedures might affect the choline concentration because the lysophospholipase D activity of autotaxin (ATX) can convert lysophosphatidylcholine ...
Ryunosuke Ohkawa, Makoto Kurano, Noboru Sakai, Tatsuya Kishimoto, Takahiro Nojiri, Koji Igarashi, Shigemi Hosogaya, Yukio Ozaki, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Shigeo Okubo, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi   +15 more
doaj   +1 more source

Effects of CDP-Choline and Choline on COX Pathway in LPS-Induced Inflammatory Response in Rats

, 2021
Background and Objective: Cytidine-5-diphosphate-choline (CDP-choline) and choline activate the cholinergic anti-inflammatory pathway in case of inflammation.
Ozbal, SEDA, Arici, MUALLA AYLİN, Baris, E., Simsek, O., Tosun, M., Gelal, AYŞE, Hamurtekin, E., Yuce, ZEYNEP, Efe, H., Oncu, S., Gelal, A., Hamurtekin, Emre, Barış, Elif, Arici, M. A., S. Ozbal, Z. Yuce, A. Gelal, E. Hamurtekin, S. Oncu, M. Tosun, O. Simsek, E. Baris, H. Efe, M.A. Arici   +23 more
core   +1 more source

Effect of ethanolamine on choline uptake and incorporation into phosphatidylcholine in human Y79 retinoblastoma cells.

Journal of Lipid Research, 1990
The effect of physiological concentrations of ethanolamine on choline uptake and incorporation into phosphatidylcholine was investigated in human Y79 retinoblastoma cells, a multipotential, undifferentiated retinal cell line that has retained many neural
M A Yorek, J A Dunlap, A A Spector, B H Ginsberg   +3 more
doaj   +1 more source

Assessment of Anti-Alzheimer Pursuit of Jambolan Fruit Extract and/or Choline against AlCl₃ Toxicity in Rats

Toxics, 2023
Jambolan fruit extract and choline were investigated for Aluminum tri chloride (AlCl3)-induced Alzheimer’s disease in rats. Thirty-six male “Sprague Dawley” rats weighing (150 ± 10 g) were allocated into six groups; the first group was fed a baseline ...
Zeinab Abdel Salam Hawash, Ensaf M. Yassien, Badriyah S. Alotaibi, Amira M. El-Moslemany, Mustafa Shukry   +4 more
doaj   +1 more source

Adaptation to Choline Deprivation: Choline Redistribution and Choline Storage

The FASEB Journal, 2006
In mammals, the only endogenous pathway for choline biosynthesis is the methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) by PE N ‐methyltransferase (PEMT). Complete choline deprivation achieved by feeding Pemt −/−
Zhaoyu Li, Luis B. Agellon, Dennis E. Vance   +2 more
openaire   +1 more source

Evaluation of differential effects of CDP-choline and choline on parasympathetic activity and changes in choline levels with heart rate variability

, 2023
Objective: Heart rate variability (HRV) is used to evaluate the autonomic activity of heartbeat. This study aimed to investigate the effects of cholinomimetic drugs cytidine diphosphate-choline (CDP-choline) and choline, on short-term HRV parameters ...
Baris E., Alpay S., Kazdagli H., Ozel H.F., Alpay, Suheda, Hasan KAZDAĞLI, Özel, Hasan Fehmi, Kazdağlı, Hasan, Şüheda ALPAY, Elif BARIŞ, Baris, Elif, Barış, Elif, Kazdagli, Hasan, Hasan Fehmi ÖZEL   +13 more
core   +1 more source

Effects of Choline on DNA Methylation and Macronutrient Metabolic Gene Expression in In Vitro Models of Hyperglycemia [PDF]

, 2016
Choline is an essential nutrient that plays an important role in lipid metabolism and DNA methylation. Studies in rodents suggest that choline may adversely affect glycemic control, yet studies in humans are lacking. Using the human hepatic and placental
Jack-Roberts, Chauntelle, Xinyin Jiang, Chauntelle Jack-Roberts, Esther Greenwald, Jiang, Xinyin, Greenwald, Esther   +5 more
core   +1 more source