Results 21 to 30 of about 262,114 (295)

Expression and Functional Characterization of Choline Transporter in Human Keratinocytes

open access: yesJournal of Pharmacological Sciences, 2009
Choline is essential for synthesis of the major membrane phospholipid phosphatidylcholine. Moreover, it serves as a precursor for synthesis of the neurotransmitter acetylcholine (ACh). Keratinocytes of the epidermis synthesize and release ACh. The uptake
Yoshihiro Uchida   +5 more
doaj   +1 more source

In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism

open access: yesViruses, 2020
Choline is an essential nutrient required for normal neuronal and muscular development, as well as homeostatic regulation of hepatic metabolism. In the liver, choline is incorporated into the main eukaryotic phospholipid, phosphatidylcholine (PC), and ...
Kaelan Gobeil Odai   +13 more
doaj   +1 more source

Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds

open access: yesFrontiers in Molecular Biosciences, 2022
Osmolytes are naturally occurring small molecular weight organic molecules, which are accumulated in large amounts in all life forms to maintain the stability of cellular proteins and hence preserve their functions during adverse environmental conditions.
Ashal Ilyas   +10 more
doaj   +1 more source

Artificial environments for the co-translational stabilization of cell-free expressed proteins [PDF]

open access: yes, 2013
An approach for designing individual expression environments that reduce or prevent protein aggregation and precipitation is described. Inefficient folding of difficult proteins in unfavorable translation environments can cause significant losses of ...
Bernhard, Frank   +3 more
core   +2 more sources

Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay

open access: yesScientific Reports, 2018
Blood choline has been proposed as a predictor of acute coronary syndrome (ACS), however different testing procedures might affect the choline concentration because the lysophospholipase D activity of autotaxin (ATX) can convert lysophosphatidylcholine ...
Ryunosuke Ohkawa   +15 more
doaj   +1 more source

Effect of ethanolamine on choline uptake and incorporation into phosphatidylcholine in human Y79 retinoblastoma cells.

open access: yesJournal of Lipid Research, 1990
The effect of physiological concentrations of ethanolamine on choline uptake and incorporation into phosphatidylcholine was investigated in human Y79 retinoblastoma cells, a multipotential, undifferentiated retinal cell line that has retained many neural
M A Yorek   +3 more
doaj   +1 more source

NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy

open access: yesPlants, 2022
Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng   +5 more
doaj   +1 more source

Response Detection of Castrate-Resistant Prostate Cancer to Clinically Utilised and Novel Treatments by Monitoring Phospholipid Metabolism [PDF]

open access: yes, 2017
The authors gratefully acknowledge funding from Grampian NHS Endowment. The use of Professor Zanda’s and Jaspar’s NMR equipment and Russell Gray’s assistance are also gratefully acknowledged.Peer reviewedPublisher ...
Alzyoud, Kholoud S   +3 more
core   +2 more sources

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]

open access: yes, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna   +3 more
core   +2 more sources

Assessment of Anti-Alzheimer Pursuit of Jambolan Fruit Extract and/or Choline against AlCl3 Toxicity in Rats

open access: yesToxics, 2023
Jambolan fruit extract and choline were investigated for Aluminum tri chloride (AlCl3)-induced Alzheimer’s disease in rats. Thirty-six male “Sprague Dawley” rats weighing (150 ± 10 g) were allocated into six groups; the first group was fed a baseline ...
Zeinab Abdel Salam Hawash   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy