Results 21 to 30 of about 168,661 (305)

Dietary Methionine Restriction Promotes Fat Browning and Attenuates Hepatic Lipid Accumulation in High-Choline-Fed Mice Associated with the Improvement of Thyroid Function

, 2023
This study aims to explore the influences of a methionine-restricted diet (MRD) on fat browning and hepatic lipid accumulation in mice fed with a high-choline diet (HCD) and their possible mechanisms.
Bowen Li (200859), Yuncong Xu, Yuhui Yang (496502), Manman Lu (1427452), Jing Qian, Yuncong Xu (7139621), Guowei Le (662057), Manman Lu, Guowei Le, Bowen Li, Yanli Xie, Yuhui Yang, Yanli Xie (3327906), Jing Qian (170232)   +13 more
core   +1 more source

Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. III. Choline transport and uptake by simple diffusion and lack of direct exchange with phosphatidylcholine

Journal of Lipid Research, 1971
The initial rate of incorporation of methyl-labeled choline into the acid-soluble pool (phosphorylcholine) of Novikoff hepatoma cells growing in suspension culture was investigated as a function of the choline concentration in the medium.
PETER G.W. PLAGEMAEN
doaj   +1 more source

Assessment of Anti-Alzheimer Pursuit of Jambolan Fruit Extract and/or Choline against AlCl₃ Toxicity in Rats

Toxics, 2023
Jambolan fruit extract and choline were investigated for Aluminum tri chloride (AlCl3)-induced Alzheimer’s disease in rats. Thirty-six male “Sprague Dawley” rats weighing (150 ± 10 g) were allocated into six groups; the first group was fed a baseline ...
Zeinab Abdel Salam Hawash, Ensaf M. Yassien, Badriyah S. Alotaibi, Amira M. El-Moslemany, Mustafa Shukry   +4 more
doaj   +1 more source

Adaptation to Choline Deprivation: Choline Redistribution and Choline Storage

The FASEB Journal, 2006
In mammals, the only endogenous pathway for choline biosynthesis is the methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) by PE N ‐methyltransferase (PEMT). Complete choline deprivation achieved by feeding Pemt −/−
Zhaoyu Li, Luis B. Agellon, Dennis E. Vance   +2 more
openaire   +1 more source

Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay

Scientific Reports, 2018
Blood choline has been proposed as a predictor of acute coronary syndrome (ACS), however different testing procedures might affect the choline concentration because the lysophospholipase D activity of autotaxin (ATX) can convert lysophosphatidylcholine ...
Ryunosuke Ohkawa, Makoto Kurano, Noboru Sakai, Tatsuya Kishimoto, Takahiro Nojiri, Koji Igarashi, Shigemi Hosogaya, Yukio Ozaki, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Shigeo Okubo, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi   +15 more
doaj   +1 more source

Performance, Egg Quality, and Yolk Antioxidant Capacity of the Laying Quail in Response to Dietary Choline Levels

Animals, 2022
The current study determined the ideal dose of choline in the diet of laying quails based on egg development, egg quality, and antioxidant capacity. A total of 120 female quails (244.7 ± 10.38 g) were randomly assigned to 6 experimental groups with 5 ...
Osman Olgun, Esra Tuğçe Gül, Gözde Kılınç, Alpönder Yıldız, Abdullah Çolak, Ainhoa Sarmiento-García   +5 more
doaj   +1 more source

Synthesis, isolation and purification of [11C]-choline [PDF]

, 2016
[11C]-choline is an effective PET tracer used for imaging of neoplastic lesions and metastases of the prostate cancer. However, its production can be a challenge for manufacturers, as it has not yet been described in Polish or European pharmacopoeia.
Michał Jadwiński, Marcin Szydło, Kamil Gorczewski, Agnieszka Chmura, Maria Sokół   +4 more
core   +1 more source

Choline Redistribution during Adaptation to Choline Deprivation [PDF]

Journal of Biological Chemistry, 2007
Choline is an important nutrient for mammals. Choline can also be generated by the catabolism of phosphatidylcholine synthesized in the liver by the methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Complete choline deprivation is achieved by feeding Pemt(-)(/)(-) mice a choline-deficient diet and is lethal
Zhaoyu, Li, Luis B, Agellon, Dennis E, Vance   +2 more
openaire   +2 more sources

Choline derivatives as natural ligands of mitochondrial nicotinic acetylcholine receptors [PDF]

The Ukrainian Biochemical Journal, 2023
Nicotinic acetylcholine receptors (nAChRs) regulate mitochondria-driven apoptosis; however, their intracellular ligands are unknown. In the present paper, we show that choline and its derivatives (phosphocholine (PC), L-α-glycerophosphocholine (G-PC) and
O. Lykhmus, M. Izmailov, M. Skok
doaj   +1 more source

Choline consumption in Norway : Dietary sources, association with one-carbon and lipid metabolism and cardiovascular disease risk [PDF]

, 2022
Background: Choline is an essential nutrient involved in a wide variety of physiological functions. Through its metabolite betaine, it is closely connected to the one-carbon metabolism, and phosphatidylcholine (PC) is essential for the formation and ...
Van Parys, Anthea
core   +1 more source