Choline has been recognized as an essential nutrient by the Food and Nutrition Board of the National Academies of Medicine since 1998. Its metabolites have structural, metabolic, and regulatory roles within the body. Humans can endogenously produce small
Steven H, Zeisel +2 more
openaire +4 more sources
Biosensors for Choline, Choline Esters and Inhibitors of Choline Esterase
A choline electrode has been developped by coupling immobilized choline oxidase to a hydrogen peroxide electrode. The coimmobilization of cholinesterase permits the measurementof acetylcholine. The excess of both enzymes results in diffusion limited electrode response for both substrates, with relative sensitivities 1: 0.6 for choline if compared with ...
Wollenberger, Ulla +4 more
openaire +2 more sources
Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei : the ethanolamine and choline kinases [PDF]
Note related output below contains correction of this paper.Ethanolamine and choline are major components of the trypanosome membrane phospholipids, in the form of GPEtn (glycero-phosphoethanolamine) and GPCho (glycerophosphocholine).
Smith, Terry K. +6 more
core +1 more source
11C-Choline positive but 18F-FDG negative pancreatic metastasis from renal cell carcinoma on PET [PDF]
2017-05Choline is a new PET tracer, which uptake may occur via a choline-specific transporter protein and be accelerated during the proliferation of tumor cells.
Nakasho, Keiji +18 more
core +1 more source
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. [PDF]
BACKGROUND: Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In humans, altered DNA methylation patterns have
Dominguez Salas, Paula +34 more
core +1 more source
Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Dominguez Salas, Paula +19 more
core +1 more source
Osmolytes are naturally occurring small molecular weight organic molecules, which are accumulated in large amounts in all life forms to maintain the stability of cellular proteins and hence preserve their functions during adverse environmental conditions.
Ashal Ilyas +10 more
doaj +1 more source
Biosynthesis of phosphatidyl choline during prenatal development of the rat lung
The biosynthesis of phosphatidyl choline in rat lung during prenatal development is of interest in connection with the mechanisms of functional development of the lung, particularly in relation to the production of lung surfactant and the control of ...
Paul A. Weinhold
doaj +1 more source
NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy
Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng +5 more
doaj +1 more source
Characterization of choline uptake in Trypanosoma brucei and involvement of a mitochondrial carrier in resistance to choline analogs [PDF]
Choline is an essential nutrient for eukaryotic cells, where it is used as precursor for the synthesis of choline-containing phospholipids, such as phosphatidylcholine (PC).
Pereira de Macêdo, Juan
core +1 more source

