Results 81 to 90 of about 262,114 (295)
Animal models of NASH: getting both pathology and metabolic context right [PDF]
, 2015 Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core +1 more source
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
PERFORMANCE OF BROILERS FED DIFFERENT DIETARY CHOLINE SOURCES AND LEVELS
Ciência Animal Brasileira, 2017 Two experiments were carried out to evaluate the bioequivalence of a commercial phosphatidylcholine source (Biocholine™) as an alternative to choline chloride and the choline requirements of broilers of a fast-growth strain. In Experiment I, 672 broilers
Giovani Farina +5 more
doaj
Tolerance and safety evaluation of N, N-dimethylglycine, a naturally occurring organic compound, as a feed additive in broiler diets [PDF]
, 2009 N, N-dimethylglycine (DMG) is a tertiary amino acid that naturally occurs as an intermediate metabolite in choline-to-glycine metabolism. The objective of the present trial was to evaluate tolerance, safety and bioaccumulation of dietary DMG in broilers ...
Kalmar, I.D. +5 more
core +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Hepatic encephalopathy: a neurochemical, neuroanatomical, and neuropsychological study. [PDF]
, 2006 Hepatic encephalopathy (HE) is normally diagnosed by neuropsychological (NP) tests, which are not very specific and do not reveal the underlying pathology.
Binesh, Nader +11 more
core +1 more source
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Current Staging Procedures in Urinary Bladder Cancer
Diagnostics, 2013 Currently computed tomography (CT) represents the most widely used standard imaging modality in muscle-invasive urinary bladder cancer. Visualization of local tumor or depth of invasion as well as lymph node staging, however, is often impaired.
Ambros J. Beer +5 more
doaj +1 more source
Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor. [PDF]
, 2017 BackgroundAlthough the contrast-enhancing (CE) lesion on T1-weighted MR images is widely used as a surrogate for glioblastoma (GBM), there are also non-enhancing regions of infiltrative tumor within the T2-weighted lesion, which elude radiologic ...
Autry, Adam +8 more
core +2 more sources