Results 191 to 200 of about 263,913 (277)

Induced‐Fit Recognition by a Calixarene–Pyrene Conjugate for Single‐ and Dual‐Wavelength Fluorescence Sensing in Water

open access: yesChemistry – A European Journal, EarlyView.
A sulfonatocalix[4]arene–pyrene conjugate functions as a fluorescence chemosensor for the optical detection of biorelevant analytes in water. Its photoinduced electron transfer (PET) response is triggered by an induced‐fit recognition mechanism. Noncovalent assembly with an additional dye affords dual‐color ratiometric signaling via competitive PET ...
Joana N. Martins   +4 more
wiley   +1 more source

E-cigarette exposure and CDP choline modulate withdrawal- induced anxiety and hormonal levels in rats. [PDF]

open access: yesSci Rep
Barakat M   +7 more
europepmc   +1 more source

Integrated and closed‐loop biorefinery strategies for efficient waste valorization and biofuel production

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Advancements in biofuel production technologies are essential for reducing global dependence on fossil fuels and addressing their overexploitation. Many valuable components of biomass, such as cellulose, hemicellulose, and lignin, remain underused in traditional biorefineries, which typically rely on a single feedstock to produce a primary ...
Marcos Paulo Patta Granado   +5 more
wiley   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

Choline attenuates NEFA-induced hepatic steatosis via GNMT regulation in hepatocytes. [PDF]

open access: yesStress Biol
Du X   +11 more
europepmc   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang   +6 more
wiley   +1 more source

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