Results 161 to 170 of about 82,281 (264)

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Fractionation of Wood Biomass With Thiolactic Acid and Choline Chloride-Based Solvent Into White Lignin for Sustainable Cooling Applications. [PDF]

ChemSusChem
Sirviö JA, Liao M, Arjmandi D, Haverinen J, Wu R, Jonsson MP, Xu C, Ämmälä A, Räty JP.   +8 more
europepmc   +1 more source

Efficient conversion of carbohydrates into 5-hydroxymethylfurfural using choline chloride-based deep eutectic solvents. [PDF]

Heliyon, 2023
Thi Ngo DK, Nguyen TH, Nguyen PN, Nguyen HT, Thi Huynh TN, Phan HB, Tran PH.   +6 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

British Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu, Yanyan Zhang, Meiling Shan, Jiaqi Cao, Zihan Fan, Zhaoxia Xu, Xiaozhen Ding, Xiaodong Liu, Lijun Shi   +8 more
wiley   +1 more source

The choline chloride/hydroquinone carboxylic acid-based DES as a novel catalyst for the green synthesis of dihydrochromeno[4,3-d]pyrimidinediones. [PDF]

Sci Rep
Jahanian Z, Habibi D, Monem A, Chegeni E.   +3 more
europepmc   +1 more source

First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing

Journal of Fish Biology, EarlyView.
Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley   +1 more source

Potentiometric Water Sensor For Eutectic Solvents Containing Choline Chloride and Ethylene Glycol. [PDF]

ACS Omega
Al-Jaafari HAS, Hartley JM, Keal ME, Abbott AP, Yang JM.   +4 more
europepmc   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source

Recovery of Lithium and Cobalt from Spent Lithium-Ion Batteries Using a Deep Eutectic Solvent Based on Choline Chloride and Oxalic Acid (Oxaline). [PDF]

Molecules
Guamán-Gualancañay JM, Aragón-Tobar CF, Moreno K, Palacios JL, Endara D.   +4 more
europepmc   +1 more source