Results 221 to 230 of about 59,547 (299)

The organic cation transporters 1 and 2 mediate ethanolamine cellular efflux and control systemic phosphatidylethanolamine level. [PDF]

J Biol Chem
Schubert J, Koca F, Barone F, Corona G, Ciarimboli G, Visentin M.   +5 more
europepmc   +1 more source

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis

Glia, Volume 74, Issue 3, March 2026.
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco, Matteo Audano, Rosa La Marca, Marta Pellegatta, Paolo Canevazzi, Mariaconcetta Cariello, Marta Falco, Silvia Pedretti, Gabriele Imperato, Alessandro Cestaro, Paola Podini, Giorgia Dina, Angelo Quattrini, Luca Massimino, Donatella Caruso, Nico Mitro, Carla Taveggia   +16 more
wiley   +1 more source

Choline-An Essential Nutrient with Health Benefits and a Signaling Molecule. [PDF]

Int J Mol Sci
Burns BC, Belani JD, Wittorf HN, Brailoiu E, Brailoiu GC.   +4 more
europepmc   +1 more source

Epilepsy Phenotype and EEG Finding of Rhythmic High‐Amplitude Delta With Superimposed Spikes (RHADS) in Succinate Dehydrogenase Deficiency

JIMD Reports, Volume 67, Issue 2, March 2026.
ABSTRACT Succinate dehydrogenase (SDH) serves a dual function as complex II of the electron transport chain and an enzyme of the tricarboxylic acid cycle. Pathogenic variants in subunits of SDH result in diverse clinical presentations, including typically autosomal recessive neurodegenerative disorders. Biallelic variants in the SDHA subunit most often
Aaron B. Bowen, Chiadika Nwanze, Cesar Alves, Lance Rodan, Anna Lecticia Pinto, Melissa A. Walker, Irina Anselm, Phillip L. Pearl   +7 more
wiley   +1 more source

Neurodevelopmental disease-causing variants in choline kinase CHKA gene couple phosphatidylcholine synthesis to oxidative stress damage and disease etiology. [PDF]

J Biol Chem
Tavasoli M, Alkandari M, Dorighello G, McPhee M, Ridgway ND, Isaac K, Sokolenko S, Maroofian R, Shukla A, Zaki MS, Houlden H, McMaster CR.   +11 more
europepmc   +1 more source

Quantification of Tryptophan and NAD+ Proton Magnetization Exchange With Water Using Downfield 1H MRS in the Human Brain at 7 T

Magnetic Resonance in Medicine, Volume 95, Issue 3, Page 1336-1344, March 2026.
ABSTRACT Purpose The purpose of this study was to investigate the effect of magnetization exchange on the measurement of tryptophan and NAD+ T1 relaxation times and to determine the magnetization exchange rates with a two‐spin system model using downfield 1H MRS spectroscopy at 7 T in human brain.
Sophia Swago, Neil E. Wilson, Mark A. Elliott, Ravinder Reddy, Walter R. Witschey, Ravi Prakash Reddy Nanga   +5 more
wiley   +1 more source

New Phenotype in Two Siblings with Familial <i>FLVCR1</i> Mutation: Neurotrophic Keratopathy. [PDF]

Turk J Ophthalmol
Dertsiz Kozan B, Alakuş MF, Polat H.
europepmc   +1 more source

The Impact of Feeding Organic Trace Minerals Using Advanced Chelate Technology on Reproductive Efficiency and Blood Parameters in Ghezel Ewes

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Supplementing the flushing diet with organic trace minerals based on advanced chelate technology enhanced the reproductive performance of ewes as compared with inorganic trace minerals. ABSTRACT Background The bioavailability of trace minerals (TM) in a diet is important for improving reproductive performance and fertility parameters.
Sedigheh Vatankhah, Marziyeh Ebrahimi, Gholamali Moghaddam, Davoud Kianifard, Akbar Taghizadeh, Reza Asadpour, Mohammad Hassan Nazaran   +6 more
wiley   +1 more source

Dietary Choline and Betaine Are Not Associated With the Risk of Type 2 Diabetes. A Systematic Review and Meta-Analysis of Observational Studies. [PDF]

J Diabetes Res
Sharifi-Zahabi E, Mohammadi S, Hajizadeh-Sharafabad F, Nasiri N, Sadeghi F, Saber A.   +5 more
europepmc   +1 more source

Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Mycophenolic acid (MPA) is a widely used immunosuppressant whose use is often limited by gastrointestinal toxicity. Gut bacterial hydrolysis of liver‐derived MPA glucuronides increases local exposure to MPA, potentially impairing epithelial barrier function and cellular metabolism.
Clarisse Brossier, François‐Ludovic Sauvage, Christel Valencia‐Schmitt, Valérie Calco, Pascal Villa, Pierre Marquet, Roland Lawson   +6 more
wiley   +1 more source