Results 41 to 50 of about 59,335 (292)

The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism

Biomolecules, 2023
The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca2+-independent ...
Sayaka Harada, Yoshitaka Taketomi, Toshiki Aiba, Mai Kawaguchi, Tetsuya Hirabayashi, Baasanjav Uranbileg, Makoto Kurano, Yutaka Yatomi, Makoto Murakami   +8 more
doaj   +1 more source

Effects of Ascorbic Acid Deficiencies on Larvae of \u3ci\u3eLymantria Dispar\u3c/i\u3e (Lepidoptera: Lymantriidae) [PDF]

, 2017
We assessed the effects of ascorbic acid and total vitamin deficiencies on growth, food processing efficiencies and survival of larval gypsy moths. Artificial diet lacking ascorbic acid did not alter performance of fourth instars, whereas diet lacking a ...
Lindroth, Richard L, Weiss, Anthony P
core   +2 more sources

Dietary Choline Mitigates High-Fat Diet-Impaired Chylomicrons Assembly via UPRer Modulated by perk DNA Methylation

Cells, 2022
High-fat diets (HFD) lead to impairment of chylomicrons (CMs) assembly and adversely influence intestinal lipid homeostasis. However, the mechanisms of HFD impairing CMs assembly have yet to be fully understood. Additionally, although choline, as a lipid-
Zhen-Yu Bai, Hua Zheng, Zhi Luo, Christer Hogstrand, Ling-Jiao Wang, Yu-Feng Song   +5 more
doaj   +1 more source

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring [PDF]

, 2017
Methylenetetrahydrofolate reductase (MTHFR) generates methyltetrahydrofolate for methylation reactions. Severe MTHFR deficiency results in homocystinuria and neurologic impairment.
Bahous, RH, Bedell, BJ, Caudill, MA, Cosin-Tomas, M, Deng, L, Greene, NDE, Ho, M-K, Jadavji, NM, Kaliman, P, Leung, K-Y, Lu, J, Malysheva, O, Pallas, M, Rozen, R   +13 more
core   +1 more source

Identification and functional analysis of choline transporter in tongue cancer: A novel molecular target for tongue cancer therapy

Journal of Pharmacological Sciences, 2016
We examined the functional characteristics of choline uptake in human tongue carcinoma using the cell line HSC-3. Furthermore, we explored the possible correlation between the inhibition of choline uptake and apoptotic cell death.
Ryohta Nishiyama, Fumiaki Nagashima, Beniko Iwao, Yuiko Kawai, Kana Inoue, Arisa Midori, Tsuyoshi Yamanaka, Hiroyuki Uchino, Masato Inazu   +8 more
doaj   +1 more source

¹H-NMR-Based Metabonomics Study to Reveal the Progressive Metabolism Regulation of SAP Deficiency on ApoE^−/− Mice

Metabolites, 2022
Atherosclerosis is the most common disease of the vascular system and the metabolic disorder is one of its important molecular mechanisms. SAP protein is found to be highly expressed in atherosclerotic blood vessels.
Qian Li, Wanting Chen, Wenbin Huang, Ranran Hou, Xinping Huang, Man Xu, Limei Que, Lijing Wang, Yongxia Yang   +8 more
doaj   +1 more source

Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice

Journal of Obesity, 2012
Previous studies demonstrated that choline supply is directly linked to high-fat-diet-induced obesity and insulin resistance in mice. The aim of this study was to evaluate if choline supply could also modulate obesity and insulin resistance caused by a ...
Gengshu Wu, Liyan Zhang, Tete Li, Gary Lopaschuk, Dennis E. Vance, René L. Jacobs   +5 more
doaj   +1 more source

Choline-deficiency fatty liver: impaired release of hepatic triglycerides

Journal of Lipid Research, 1968
After intravenous injection of palmitate-1-14C to rats fed a choline-deficient (CD) or choline-supplemented (CS) diet for 15-18 hr, liver triglycerides became labeled very rapidly.
B. Lombardi, P. Pani, F.F. Schlunk
doaj   +1 more source

The efficacy of choline as an adjuvant in the therapy of Laennec's cirrhosis [PDF]

, 1951
Thesis (M.D.)—Boston ...
Bednarz, Wallace
core  

Electroactive Metal–Organic Frameworks for Electrocatalysis

Advanced Functional Materials, EarlyView.
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska, Yutong Luo, Ruyan Zhao, Jianjun Zhang, Mingchao Wang, Xinliang Feng, Eike Brunner, Stefan Kaskel   +7 more
wiley   +1 more source