Results 71 to 80 of about 14,687,166 (179)

Topography of choline acetyltransferase immunoreactive neurons and fibers in the rat spinal cord.

open access: yes, 1986
The topography of choline acetyltransferase immunoreactivity was studied in the rat spinal cord with a monoclonal antibody. Cholinergic fibers were most prominent in lamina III of the dorsal horn and originated from cholinergic neurons within the spinal ...
Iversen, SD, Borges, LF, Iversen, Susan
core   +1 more source

Presynaptic Congenital Myasthenic Syndromes

open access: yesMuscle &Nerve, Volume 74, Issue S1, Page S41-S51, September 2026.
ABSTRACT Presynaptic congenital myasthenic syndromes (CMS) encompass a large number of rare neurologic disorders caused by impaired release of acetylcholine (ACh) from motor nerve terminals. There are two main groups of presynaptic CMS: one in which the amount of ACh in synaptic vesicles (SV) is diminished and another in which the mechanism of synaptic
Ricardo A. Maselli
wiley   +1 more source

Quantitative distribution of choline acetyltransferase and acetylcholinesterase activities in the rat cochlear nucleus.

open access: yes, 1981
Within the cochlear nucleus of the rat, as well as some nearby regions, quantitative histochemical mapping procedures were used to construct maps of the distributions of choline acetyltransferase and acetylcholinesterase activities.
D A Godfrey, F M Matschinsky
core   +1 more source

Aging Alters Hair Cell Physiological Properties in Mice With Late‐Onset Age‐Related Hearing Loss

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Hidden hearing loss during aging is associated with peripheral auditory system decline. We discovered that aging sensory hair cells decrease in size. In addition, inner hair cells exhibit a reduced K+ current carried out by BK channels, accompanied by an elevated resting membrane potential, suggesting an age‐related functional impairment.
Piece Yen   +5 more
wiley   +1 more source

Neuroinflammatory and Motor Alterations in LRRK2*G2019S Transgenic Mice Without Enhanced Vulnerability to Aging or Chronic MPTP‐Induced Nigrostriatal Neurodegeneration

open access: yesJournal of Neurochemistry, Volume 170, Issue 9, September 2026.
LRRK2 G2019S mutation is the most common genetic cause of Parkinson's disease but its contribution to nigrostriatal neurodegeneration, particularly in response to mitochondrial dysfunction, remains unclear. hLRRK2*G2019S transgenic mice exhibited early microglial activation and motor alterations, but not increased dopaminergic nigrostriatal ...
Roberto García‐Swinburn   +8 more
wiley   +1 more source

Trans-synaptic induction of choline acetyltransferase in the preganglionic neuron of the peripheral sympathetic nervous system

open access: yes, 2020
OESCH, FRANZ : Trans-synaptic induction of choline acetyltransferase in the preganglionic neuron of the peripheral nervous ...
Franz Oesch
core  

Topical Donepezil for Cholinergic Modulation in Chronic Wound Repair

open access: yesWound Repair and Regeneration, Volume 34, Issue 5, September/October 2026.
ABSTRACT Chronic wounds result from combined defects in vascular perfusion, inflammatory resolution, and epithelial repair. The skin's non‐neuronal cholinergic system (NNCS), formed by keratinocytes, endothelial cells, fibroblasts, and immune cells that synthesise and respond to acetylcholine (ACh), helps coordinate these processes through muscarinic ...
Hui‐Qi Qu   +2 more
wiley   +1 more source

Serum metabolomics signatures after an acute bout of combined traditional or high‐intensity tactical training in young adults

open access: yesPhysiological Reports, Volume 14, Issue 18, September 2026.
Abstract Alternative exercise prescriptions and doses would be expected to result in distinct signatures due to differences in duration and intensity. We tested two novel combined endurance and resistance exercise regimens to understand how differing prescriptions alter the timecourse of metabolomics response.
Zachary A. Graham   +8 more
wiley   +1 more source

Deletion of choline acetyltransferase in enteric neurons results in postnatal intestinal dysmotility and dysbiosis

open access: yes, 2018
Deletion of choline acetyltransferase in enteric neurons results in postnatal intestinal dysmotility and ...
Ketrija Touw (19471255)   +7 more
core  

Trimethyltin Increases Choline Acetyltransferase in Rat Hippocampus

open access: yes, 1991
The environmental neurotoxin trimethyltin (TMT) destroys parts of the hippocampal formation as well as the entorhinal cortex but leaves the septal cholinergic projection to the hippocampus and dentate gyrus intact.
Hoover, Donald B.   +2 more
core   +1 more source

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