Immunization against specific fragments of neurotrophin p75 receptor protects forebrain cholinergic neurons in the olfactory bulbectomized mice [PDF]
, 2016 Alzheimer's disease (AD) is characterized by progressive cognitive impairment associated with marked cholinergic neuron loss and amyloid-β (Aβ) peptide accumulation in the brain.
Bobkova, Natalia +10 more
core +1 more source
Evaluation of the endogenous glucocorticoid hypothesis of denervation atrophy [PDF]
The effects are studied of the oral administration of RU38486, a potent selective glucocorticoid antagonist, on muscle weight, non-collagen protein content, and selected enzyme activities (choline acetyltransferase, glucose 6-phosphate dehydrogenase, and
Konagaya, Masaaki +2 more
core +1 more source
Acetylcholine release and the cholinergic genomic locus [PDF]
, 2018 Choline acetyltransferase and vesicular acetylcholine-transporter genes are adjacent and coregulated. They define a cholinergic locus that can be turned on under the control of several factors, including the neurotrophins and the cytokines. Hirschprung's
Dunant, Yves, Israël, Maurice
core
Dopamine D_2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive 4 nicotinic receptors via a cholinergic-dependent mechanism [PDF]
, 2010 Recent studies suggest that high-affinity neuronal nicotinic acetylcholine receptors (nAChRs) containing α4 and β2 subunits (α4β2*) functionally interact with G-protein-coupled dopamine (DA) D_2 receptors in basal ganglia.
Andrew R. Tapper +18 more
core +3 more sources
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
MedComm, Volume 7, Issue 6, June 2026.Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Features of cholinergic cardia regulation under conditions of hypokinesia [PDF]
The features of cholinergic processes in the heart on the 4th, 8th, 16th and 30th days of hypokinesia were studied in experiments on 382 albino rats.
Babinskaya, L. N. +5 more
core +1 more source
Substitution of natural sensory input by artificial neurostimulation of an amputated trigeminal nerve does not prevent the degeneration of basal forebrain cholinergic circuits projecting to the somatosensory cortex [PDF]
, 2014 Peripheral deafferentation downregulates acetylcholine (ACh) synthesis in sensory cortices. However, the responsible neural circuits and processes are not known.
Herrera Rincón, Celia +1 more
core +2 more sources
Aging Cell, Volume 25, Issue 6, June 2026.Surgery‐induced MS/vDB → DG cholinergic decline impairs hippocampal neurogenesis and memory in aged mice; galantamine‐mediated cholinergic potentiation or sustained chemogenetic activation rescues these deficits, highlighting therapeutic potential for POCD.
Lei Lei +8 more
wiley +1 more source
Computerized tomography myelography with coronal and oblique coronal view for diagnosis of nerve root avulsion in brachial plexus injury [PDF]
, 2007 Background The authors describe a new computerized tomography (CT) myelography technique with coronal and oblique coronal view to demonstrate the status of the cervical nerve rootlets involved in brachial plexus injury.
Hattori Yasunori +3 more
core +2 more sources
GCB Bioenergy, Volume 18, Issue 6, June 2026.Switchgrass cultivation sustained biomass production while rapidly improving soil structure and reducing salinity in coastal saline‐alkali soils. These changes reshaped microbial communities through environmental filtering, establishing plant‐soil‐microbe feedbacks that support both bioenergy production and ecological restoration.
Aoxiang Chang +17 more
wiley +1 more source