Results 31 to 40 of about 7,719 (129)

Molecular Ontology Predicts Output Connections From the Nucleus of the Solitary Tract

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
The nucleus of the solitary tract (NTS) integrates visceral inputs to coordinate appetite and digestion, breathing, and cardiorespiratory reflexes. Using cell‐type‐specific tracing, we show that excitatory Lmx1b neurons project broadly to brainstem and forebrain targets, whereas inhibitory output remains largely brainstem‐restricted. Catecholaminergic (
Silvia Gasparini, Haidong Zhu, Ana Sofia Peraza Munuzuri, Mya L. Leuang, Frederico S. Fazan, Joel C. Geerling   +5 more
wiley   +1 more source

Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV, James M. Salvatore, Matthew J. Sticco, Keaven Caro, J. Wesley Maddox, Angie Huang, Brenna C. McAllister, Christopher B. O'Connell, Siu‐Pok Yee, Amy Lee, Susanne Ressl, David C. Martinelli, Alexander C. Jackson   +12 more
wiley   +1 more source

An Efficient Method for Neuron‐Like Differentiation of SH‐SY5Y Neuroblastoma Cells Using Retinoic Acid and Laminin‐Rich Extracellular Matrix

genesis, Volume 64, Issue 4, August 2026.
ABSTRACT The human neuroblastoma cell line SH‐SY5Y is widely used in vitro as a model due to its ability to acquire neuron‐like properties. Conventional differentiation protocols often rely on retinoic acid (RA), which can lead to limited stability of neuronal‐like phenotypes over time.
Marina Mantellatto Grigoli, Bianca Cruz Pachane, Angelina Maria Fuzer, Sabrina Dorta de Oliveira, Ana Beatriz Aparecida Targas, Vanessa Alexandre‐Silva, Heloisa Sobreiro Selistre‐de‐Araujo, Patricia Regina Manzine, Marcia Regina Cominetti   +8 more
wiley   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

Choline O-Acetyltransferase [PDF]

, 2020
openaire   +1 more source

Depletion of NAT10 in T cells attenuates metabolic dysfunction-associated steatohepatitis in mice. [PDF]

Hepatol Commun
Yang Y, Lu J, Ma M, Zhou J, Wang E, Lu Y, Dai Z, Zhou B, Li Y.   +8 more
europepmc   +1 more source

Molecular Diversity and Functional Implications of Mammalian Choline Acetyltransferases in Neuronal and Non-Neuronal Cells. [PDF]

Int J Mol Sci
Marinova D, Trifonov S.
europepmc   +1 more source

In-vitro modelling of Alzheimer's disease using cholinergic neurons derived from human neuroblastoma (SH-SY5Y) retinoic acid-induced differentiation. [PDF]

Mol Biol Rep
Zainuddin MS, Bai Magalingam K, Pamidi N, Azman AS, Bhuvanendran S.   +4 more
europepmc   +1 more source

Protective Effects of a Propolis-<i>Petasites japonicus</i> Mixture on Scopolamine-Induced Memory Impairment in Mice. [PDF]

J Microbiol Biotechnol
Kim MY, Shin JY, Lim JH, Park JH, Hur YK, Yun SI, Cho BO, Jang SI.   +7 more
europepmc   +1 more source

Differential Effects of Hypoglycemia and Excitotoxic Signals on SN56 Septal Cholinergic Neuronal Cells. [PDF]

Cells
Gul-Hinc S, Szutowicz A, Ronowska A, Jankowska-Kulawy A.   +3 more
europepmc   +1 more source