Results 181 to 190 of about 285,894 (338)

The cholinergic hypothesis of Alzheimer’s disease: a review of progress

Journal of Neurology Neurosurgery & Psychiatry, 1999
P. Francis, A. Palmer, M. Snape, G. Wilcock   +3 more
semanticscholar   +1 more source

Type‐Specific Single‐Neuron Analysis Reveals Mitochondrial DNA Maintenance Failure Affecting Atrophying Pontine Neurons Differentially in Lewy Body Dementia Syndromes

Aging Cell, EarlyView.
(a) Mitochondria contain wild‐type (black)/mutant (red) mtDNA; exceeding the mtDNA mutation threshold compromises OXPHOS, potentially driving degeneration of neurons vulnerable to age‐related neurodegenerative disease. Cellular compensations that is, mtDNA copy number upregulation and crosstalk with nuclear DNA may fail, driving neurodegeneration ...
Eloise J. Stephenson, Laura J. Bailey, Stephen Gentleman, Helen Tuppen, Istvan Bodi, Claire Troakes, Christopher M. Morris, Tony M. Carr, Sarah Guthrie, Joanna L. Elson, Ilse S. Pienaar   +10 more
wiley   +1 more source

Cholinergic modulation of the hippocampal region and memory function

Journal of Neurochemistry, 2017
J. Haam, J. Yakel
semanticscholar   +1 more source

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi, Priya Atodaria, Edmund Appiah‐Kubi, Zainab Shah, Elpidio Marlon Garcia   +4 more
wiley   +1 more source

Progress in cholinergic biology: Model cholinergic synapses [PDF]

Trends in Pharmacological Sciences, 1983
  +8 more sources

Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux. [PDF]

Nat Commun
Chuang KH, Zhou XA, Xia Y, Li Z, Qian L, Eeles E, Ngiam G, Fripp J, Coulson EJ.   +8 more
europepmc   +1 more source

Efficacy of interventions for myopia control in children: A systematic review with network meta‐analyses

Acta Ophthalmologica, EarlyView.
Abstract To determine the effectiveness of various interventions in reducing myopia progression in children. Literature databases were searched on December 2, 2023: PubMed, Embase, the Cochrane Central, Web of Science Core Collection, BIOSIS Previews, Current Contents Connect, Data Citation Index, Derwent Innovations Index, KCI‐Korean Journal Database,
Diana Chabané Schmidt, Anders Hvid‐Hansen, Nina Jacobsen, Trine Møldrup Jakobsen, Per Michael Larsen, Kjersti Kristin Lindblad, Flemming Møller, Annette Slyngborg, Yousif Subhi, Line Kessel   +9 more
wiley   +1 more source

The endogenous cholinergic system overwhelmingly predominates over the exogenous system in regulating ventricular bioelectrical homeostasis. [PDF]

Eur Heart J
Xie D, Liu Y, Chen YH.
europepmc   +1 more source

Spliceosome protein alterations differentiate hubs of the default mode connectome during the progression of Alzheimer's disease

Brain Pathology, EarlyView.
Default mode network (DMN) consists, in part, of the frontal (FC), precuneus (PreC), and posterior cingulate cortex (PCC), which plays a critical role in episodic memory and retrieval of autobiographical memories, displays spatiotemporal differences in the onset of amyloid and hypometabolism that reflects tau neurodegeneration and loss of connectivity ...
Sylvia E. Perez, Muhammad Nadeem, Bin He, Jennifer C. Miguel, David G. Moreno, Marta Moreno‐Rodriguez, Michael Malek‐Ahmadi, Chadwick M. Hales, Elliott J. Mufson   +8 more
wiley   +1 more source

Effects of Cholinergic and Opioid Antagonists on In Vitro Release of Met-Enkephalin, Somatostatin and Insulin-like Growth Factor-1 by and PENK Expression in Crop, Proventriculus and Duodenum of Newly Hatched Chickens. [PDF]

Animals (Basel)
Scanes CG, Jaszcza K, Gajewska A, Pierzchala-Koziec K.   +3 more
europepmc   +1 more source