Functional and molecular characterization of metabotropic glutamate receptors expressed in rat striatal cholinergic interneurones [PDF]
Matt I. Bell +2 more
openalex +1 more source
Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari +6 more
wiley +1 more source
A role for the cholinergic neuron circadian clock in RNA metabolism and mediating neurodegeneration. [PDF]
Tam SB +7 more
europepmc +1 more source
Chronic allergen exposure enhances cholinergic neurotransmission in sensitized guinea-pigs [PDF]
N Kageyama +8 more
openalex +1 more source
Parkinson's Disease and Salivary Issues: A Survey
ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction.
Beau D. M. van Dijk +3 more
wiley +1 more source
Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson +4 more
wiley +1 more source
Stereotactic lesioning of cholinergic cells by injection of ME20.4 Saporin in the nucleus basalis of Meynert in a rhesus monkey (Macaca mulatta). [PDF]
Nazmuddin M +7 more
europepmc +1 more source
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams +6 more
wiley +1 more source
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer +4 more
wiley +1 more source

