Results 181 to 190 of about 169,479 (311)

The role of the oral microbiome, host response, and periodontal disease treatment in Alzheimer's disease: A primer

Periodontology 2000, EarlyView.
Abstract Background Alzheimer‘s disease (AD) is the leading cause of cognitive impairment and dementia in elderly patients worldwide. There is increasing evidence that periodontal disease may have an important role in the complex, multifactorial pathogenesis of AD. Aim This narrative review aims to (1) highlight the current understanding of the role of
Jaclyn C. Chalmers, Yvonne L. Hernandez‐Kapila   +1 more
wiley   +1 more source

Finding the Words: How Does the Aging Brain Process Language? A Focused Review of Brain Connectivity and Compensatory Pathways

Topics in Cognitive Science, EarlyView.
Abstract As people age, there is a natural decline in cognitive functioning and brain structure. However, the relationship between brain function and cognition in older adults is neither straightforward nor uniform. Instead, it is complex, influenced by multiple factors, and can vary considerably from one person to another.
Monica Baciu, Elise Roger
wiley   +1 more source

Cholinergic Dynamics in the Septo-hippocampal System Provide Phasic Multiplexed Signals for Spatial Novelty and Correlate with Behavioral States. [PDF]

J Neurosci
Moghadam FF, Gutiérrez-Guzmán BE, Zheng X, Parsa M, Hozyen LM, Dannenberg H.   +5 more
europepmc   +1 more source

Cholinergic synaptic plasticity shapes resilience and vulnerability to tau [PDF]

Kate M. Onuska, Lauren A Devito, Hayley R. C. Shanks, Qi Qi, Alycia M Crooks, Roy A.M. Haast, Tallulah Andrews, Kayla Williams, Flávio H. Beraldo, Ting Qiu, Alfonso Fajardo-Valdez, Alfie Wearn, Gary R. Turner, Étienne Aumont, Matthew S. Fox, Matthew S. Fox, Timothy J. Bussey, Timothy J. Bussey, Lisa M. Saksida, John C.S. Breitner, John C.S. Breitner, Jean‐Paul Soucy, Sylvia Villeneuve, Marc‐André Bédard, Sylvia Villeneuve, R. Nathan Spreng, Taylor W. Schmitz, R. Nathan Spreng, Taylor W. Schmitz, for the PREVENT-AD Research Group   +29 more
openalex   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]

Int J Mol Sci
Girón-Pérez MI, Ramírez-Ibarra KM, Covantes-Rosales CE, Girón-Pérez DA, Razura-Carmona FF, Contis-Montes de Oca A, Morales-Montor J, Pavón L, Toledo-Ibarra GA.   +8 more
europepmc   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

The Journal of Physiology, EarlyView.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

Modelling cholinergic and dopaminergic function over time in Parkinson's disease with and without GBA1 variants. [PDF]

NPJ Parkinsons Dis
Slingerland S, de Meyer EKR, van der Horn HJ, Carli G, Slomp AC, d'Angremont E, Boertien JM, Goethals I, Meles SK, van der Zee S, van Laar T.   +10 more
europepmc   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Transcriptional responses to chronic oxidative stress require cholinergic activation of G-protein-coupled receptor signaling

Kasturi Biswas, Constance M. Moore, Harry C. Rogers, Khursheed A. Wani, Read Pukkila-Worley, Daniel P Higgins, Amy K. Walker, Gregory P. Mullen, James B. Rand, Michael M. Francis   +9 more
openalex   +1 more source