Results 241 to 250 of about 285,894 (338)

Cholinergic signaling to CA1 astrocytes controls fear extinction. [PDF]

Sci Adv
Li Y, Li L, Wang Y, Li X, Ding X, Li L, Fei F, Zheng Y, Cheng L, Duan S, Parpura V, Wang Y, Chen Z.   +12 more
europepmc   +1 more source

Enteric neuropathy and the vagus nerve: Therapeutic implications

Neurogastroenterology &Motility, EarlyView.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley   +1 more source

Partial normalization of hippocampal oscillatory activity during sleep in TgF344-AD rats coincides with increased cholinergic synapses at early-plaque stage of Alzheimer's disease. [PDF]

Acta Neuropathol Commun
Berg MVD, Heymans L, Toen D, Adhikari MA, Audekerke JV, Verschuuren M, Pintelon I, Vos WH, Linden AV, Verhoye M, Keliris GA.   +10 more
europepmc   +1 more source

Central Cholinergic Neurons Are Rapidly Recruited by Reinforcement Feedback

Cell, 2015
B. Hangya, S. Ranade, Maja Lorenc, Adam Kepecs   +3 more
semanticscholar   +1 more source

The human colon: Evidence for degenerative changes during aging and the physiological consequences

Neurogastroenterology &Motility, EarlyView.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Brain cholinergic terminal density utilizing [¹⁸F]-fluoroethoxybenzovesamicol PET in adults with Down's syndrome: Relationship to amyloid PET and cognitive performance. [PDF]

Alzheimers Dement
Russell JK, Conley AC, Boyd BD, Begnoche JP, Schlossberg R, Stranick A, Rosenberg AJ, Acosta LMY, Martin D, Neal Y, Rafii MS, Dumas J, Newhouse PA.   +12 more
europepmc   +1 more source

Genomic stress in diseases stemming from defects in the second brain

Neurogastroenterology &Motility, EarlyView.
The enteric nervous system, a.k.a., second brain, is subject to a range of genotoxic exposures that include intrinsic oxidative stress and extrinsic agents associated with ingested foods, inflammation, and dysbiosis. Resulting DNA damage, if left unrepaired, can induce cell dysfunction or death, resulting in gut abnormalities and enteric neuropathy ...
Lobke Marie M. Mombeek, Werend Boesmans, David M. Wilson III   +2 more
wiley   +1 more source

Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS. [PDF]

Glia
Kautzmann S, Rey S, Krebs A, Klämbt C.
europepmc   +1 more source

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

Neurogastroenterology &Motility, EarlyView.
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley   +1 more source

Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca²⁺ ATPase to promote recycling of synaptic vesicles. [PDF]

Elife
Seidenthal M, Redzovic J, Liewald JF, Rentsch D, Shapiguzov S, Schuh N, Rosenkranz N, Eimer S, Gottschalk A.   +8 more
europepmc   +1 more source