Results 11 to 20 of about 176,034 (239)

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Tasker, Paul N., Kennedy, Charles, Westfall, Timothy D., Gallagher, Gemma   +3 more
core   +4 more sources

Prolonged cholinergic enrichment influences regional cortical activation in early Alzheimer's disease [PDF]

, 2008
Neuroimaging studies of cholinesterase inhibitor (ChEI) treatment in Alzheimer's disease (AD) indicate that the short and long term actions of ChEIs are dissimilar. fMRI studies of the ChEI rivastigmine have focused on its short term action.
Shanks, Michael F, Venneri, Annalena, McGeown, William J   +2 more
core   +4 more sources

Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?

Frontiers in Pharmacology, 2021
Social species form organizations that support individuals because the consequent social behaviors help these organisms survive. The isolation of these individuals may be a stressor. We reviewed the potential mechanisms of the effects of social isolation
Jaromir Myslivecek
doaj   +1 more source

Cholinergic Mechanisms in Spinal Locomotion - Potential Target for Rehabilitation Approaches

Frontiers in Neural Circuits, 2014
Previous experiments implicate cholinergic brainstem and spinal systems in the control of locomotion. Our results demonstrate that the endogenous cholinergic propriospinal system, acting via M2 and M3 muscarinic receptors, is capable of consistently ...
L M Jordan, J R McVagh, B R Noga, A M Cabaj, A M Cabaj, H eMajczyński, Urszula eSlawinska, J eProvencher, H eLeblond, S eRossignol   +9 more
doaj   +1 more source

Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]

, 2011
The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Warburton, E Clea, Endean, E. P. E., Fontaine-Palmer, N. S., Chris J. Tinsley, Endean, Emma P E, Aggleton, John P, John P. Aggleton, Emma P.E. Endean, Vincent, Maria, Aggleton, John Patrick, Maria Vincent, E. Clea Warburton, Nadine S. Fontaine-Palmer, Brown, M. W., Malcolm W. Brown, Tinsley, Chris J, Brown, Malcolm W, Vincent, M., Tinsley, C. J., Fontaine-Palmer, Nadine S, Warburton, E. C.   +20 more
core   +1 more source

Rapid Desensitization with Autologous Sweat in Cholinergic Urticaria

Allergology International, 2011
Background: The majority of patients with cholinergic urticaria presents with strong hypersensitivity to autologous sweat. Patients with severe cholinergic urticaria are frequently resistant to H1 antagonists which are used in conventional therapies for ...
Takeshi Kozaru, Atsushi Fukunaga, Kumiko Taguchi, Kanako Ogura, Tohru Nagano, Masahiro Oka, Tatsuya Horikawa, Chikako Nishigori   +7 more
doaj   +1 more source

Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease [PDF]

, 2015
Background Patients with advanced Parkinson's disease (PD) often present with axial symptoms, including postural- and gait difficulties that respond poorly to dopaminergic agents.
Pienaar, Ilse, De Paola, V, Gretenkord, Sabine, David Dexter (3572210), Sabine Gretenkord, Withers, Dominic, Ilse Pienaar (4504357), Dominic Withers (3572216), Gartside, Sarah, De Paola, Vincenzo, Puneet Sharma, Ilse S. Pienaar, Puneet Sharma (3572222), Sharma, Puneet, Dominic Withers, Sabine Gretenkord (3572213), David T. Dexter, Vincenzo De Paola, Joanna L. Elson, Ilse Pienaar (3572219), Joanna L Elson (16036517), Sarah Gartside (3572225), Dexter, David, Elson, Joanna, Sarah E. Gartside, Joanna Elson (271089), Vincenzo De Paola (275215), Sarah E Gartside (16264538), David T Dexter (9237410)   +28 more
core   +1 more source

Eosinophil-mediated cholinergic nerve remodeling [PDF]

, 2006
Eosinophils are observed to localize to cholinergic nerves in a variety of inflammatory conditions such as asthma, rhinitis, eosinophilic gastroenteritis, and inflammatory bowel disease, where they are also responsible for the induction of cell ...
McLean, W.G., Anthony G. Fenech, Madziar, B., Madziar, Beata, Durcan, Niamh, Gleich, G.J., Walsh, M., Fenech, Anthony G., McLean, Graham W., Jan Blusztajn, Gerard J. Gleich, Gleich, Gerard J., Niamh Durcan, Hall, Ian P., Beata Madziar, Walsh, Marie-Therese, Hall, I.P., Ian P. Hall, Durcan, N., Costello, Richard W., Richard W. Costello, Marie-Therese Walsh, McGarvey, Lorcan, Costello, R.W., Fenech, A.G., W. Graham McLean, Lorcan McGarvey, Blusztain, J., Blusztajn, Jan   +28 more
core   +1 more source

Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia.

PLoS ONE, 2019
In early-onset generalized torsion dystonia, caused by a GAG deletion in TOR1A (DYT1), enhanced striatal cholinergic activity has been suggested to be critically involved. Previous studies have shown increased acetylcholine levels in the striatum of DYT1
Franziska Richter, Laura Klein, Christin Helmschrodt, Angelika Richter   +3 more
doaj   +1 more source

Unilateral mydriasis secondary to ipratropium bromide in a critically ill patient

Journal of Emergencies, Trauma and Shock, 2012
Unilateral dilated pupil in a critical patient under sedation is an important clinical sign that requires prompt evaluation. An exhaustive assessment must be performed, including neurological examination and imaging tests, and pharmacological causes must
Luciano Santana-Cabrera, Ernesto José Fernández-Tagarro, Beatriz del Amo-Nolasco, Nieves Jaén-Sánchez, Juan José Cáceres-Agra   +4 more
doaj   +1 more source