Results 11 to 20 of about 29,186 (237)
Successful cholinergic-noradrenergic pharmacotherapy for obstructive sleep apnea (OSA) is thought to be due to effects at the hypoglossal motor nucleus (HMN). Clinical efficacy varies with muscarinic-receptor (MR) subtype affinities. We hypothesized that
Sepehr Niakani +3 more
doaj +1 more source
Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?
Social species form organizations that support individuals because the consequent social behaviors help these organisms survive. The isolation of these individuals may be a stressor. We reviewed the potential mechanisms of the effects of social isolation
Jaromir Myslivecek
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Cholinergic Mechanisms in Spinal Locomotion - Potential Target for Rehabilitation Approaches
Previous experiments implicate cholinergic brainstem and spinal systems in the control of locomotion. Our results demonstrate that the endogenous cholinergic propriospinal system, acting via M2 and M3 muscarinic receptors, is capable of consistently ...
L M Jordan +9 more
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Rapid Desensitization with Autologous Sweat in Cholinergic Urticaria
Background: The majority of patients with cholinergic urticaria presents with strong hypersensitivity to autologous sweat. Patients with severe cholinergic urticaria are frequently resistant to H1 antagonists which are used in conventional therapies for ...
Takeshi Kozaru +7 more
doaj +1 more source
In early-onset generalized torsion dystonia, caused by a GAG deletion in TOR1A (DYT1), enhanced striatal cholinergic activity has been suggested to be critically involved. Previous studies have shown increased acetylcholine levels in the striatum of DYT1
Franziska Richter +3 more
doaj +1 more source
Unilateral mydriasis secondary to ipratropium bromide in a critically ill patient
Unilateral dilated pupil in a critical patient under sedation is an important clinical sign that requires prompt evaluation. An exhaustive assessment must be performed, including neurological examination and imaging tests, and pharmacological causes must
Luciano Santana-Cabrera +4 more
doaj +1 more source
OBJECTIVES: Primary hyperhidrosis usually affects the hands, armpits, feet and cranio-facial region. Sweating in other areas is common in secondary hyperhidrosis (after surgery or in specific clinical conditions). Oxybutynin has provided good results and
Marcelo Passos Teivelis +5 more
doaj +1 more source
A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine via CB1 cannabinoid receptor activation. [PDF]
BACKGROUND: Cocaine increases the level of endogenous dopamine (DA) in the striatum by blocking the DA transporter. Endogenous DA modulates glutamatergic inputs to striatal neurons and this modulation influences motor activity.
Alessandro Tozzi +14 more
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Evaluation of Different Combined Regimens in the Treatment of Cholinergic Urticaria
Background Cholinergic urticaria is uncommon and accounts for 10% of all young adults. To date, there is no effective therapy for cholinergic urticaria.Objective To determine the therapeutic efficacy of different drug combinations in the treatment of ...
Abdulghani M. Alsamarai, MD, PhD +2 more
doaj +1 more source
The α7 nicotinic acetylcholine receptor (nAChR) is widely distributed in the central and peripheral nervous systems and is closely related to a variety of nervous system diseases and inflammatory responses.
Yao Tan +5 more
doaj +1 more source

