Cholinergic Antagonists and Behavioral Disturbances in Neurodegenerative Diseases. [PDF]
Int J Mol Sci, 2023 Cholinergic antagonists interfere with synaptic transmission in the central nervous system and are involved in pathological processes in patients with neurocognitive disorders (NCD), such as behavioral and psychological symptoms of dementia (BPSD).
Mahmoudi R +6 more
europepmc +7 more sources
Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals [PDF]
Journal of Veterinary Pharmacology and Therapeutics, 2002 Oxindole alkaloids in the paraherquamide/marcfortine family exhibit broad‐spectrum anthelmintic activity that includes drug‐resistant strains of nematodes. Paraherquamide (PHQ), 2‐deoxoparaherquamide (2DPHQ), and close structural analogs of these compounds rapidly induce flaccid paralysis in parasitic nematodesin vitro, without affecting adenosine ...
Erich Zinser +8 more
semanticscholar +4 more sources
Characterizing the Access of Cholinergic Antagonists to Efferent Synapses in the Inner Ear [PDF]
Frontiers in Neuroscience, 2021 Stimulation of cholinergic efferent neurons innervating the inner ear has profound, well-characterized effects on vestibular and auditory physiology, after activating distinct ACh receptors (AChRs) on afferents and hair cells in peripheral endorgans ...
Choongheon Lee +8 more
doaj +2 more sources
Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
Frontiers in Immunology, 2021 Neurological and immunological signals constitute an extensive regulatory network in our body that maintains physiology and homeostasis. The cholinergic system plays a significant role in neuroimmune communication, transmitting information regarding the ...
Namrita Halder, Girdhari Lal
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Effects of cholinergic antagonists on ghrelin release and expression in the crop, proventriculus, and duodenum of newly hatched chickens [PDF]
Frontiers in PhysiologyThe aim of this study was to evaluate the effect of the cholinergic receptor antagonists on ghrelin (GHRL) expression and release from parts of the gastrointestinal system in an unique animal model—newly hatched chickens.
Colin Guy Scanes +2 more
doaj +2 more sources
Coordinated release of ATP and ACh from cholinergic synaptosomes and its inhibition by calmodulin antagonists [PDF]
Journal of Neuroscience, 1987 Isolated cholinergic synaptosomes from elasmobranch electric organ release both ACh and ATP when depolarized in the presence of calcium. The conditions that trigger ATP release are the same as those known to stimulate neurosecretion.
Eugene J. Schweitzer
openalex +2 more sources
Effects of Cholinergic and Opioid Antagonists on In Vitro Release of Met-Enkephalin, Somatostatin and Insulin-like Growth Factor-1 by and PENK Expression in Crop, Proventriculus and Duodenum of Newly Hatched Chickens [PDF]
AnimalsThe gastrointestinal (GI) tract is under neural, endocrine and paracrine control. The release (basal and in the presence of either cholinergic and opioid antagonists) of Met-enkephalin, insulin-like growth factor 1 (IGF-1) and somatostatin (SRIF) was ...
Colin G. Scanes +3 more
doaj +2 more sources
Effect of cholinergic antagonists on sympathetic ganglionic transmission of vasomotor reflexes from the carotid baroreceptors and chemoreceptors of the dog. [PDF]
Journal of Physiology, 1978 C G Henderson, A. Ungar
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Frontiers in Immunology, 2021 The cholinergic system is present in both bacteria and mammals and regulates inflammation during bacterial respiratory infections through neuronal and non-neuronal production of acetylcholine (ACh) and its receptors.
Leon Islas-Weinstein +9 more
doaj +1 more source