Results 21 to 30 of about 176,034 (239)

Perioperative uses of histamine antagonists [PDF]

open access: yes, 1990
Histamine release and adverse pseudoallergic/allergic reactions during the perioperative period occur frequently. The incidence of such reactions is 20%-30% for all grades of severity, 1%-5% for systemic reactions, and 0.1%-0.5% for life-threatening ...
Lorenz, Wilfried   +3 more
core   +1 more source

Treatment of uncommon sites of focal primary hyperhidrosis: experience with pharmacological therapy using oxybutynin

open access: yesClinics, 2014
OBJECTIVES: Primary hyperhidrosis usually affects the hands, armpits, feet and cranio-facial region. Sweating in other areas is common in secondary hyperhidrosis (after surgery or in specific clinical conditions). Oxybutynin has provided good results and
Marcelo Passos Teivelis   +5 more
doaj   +1 more source

A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine via CB1 cannabinoid receptor activation. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Cocaine increases the level of endogenous dopamine (DA) in the striatum by blocking the DA transporter. Endogenous DA modulates glutamatergic inputs to striatal neurons and this modulation influences motor activity.
Alessandro Tozzi   +14 more
doaj   +1 more source

Critical role of the cholinergic system for object-in-place associative recognition memory [PDF]

open access: yes, 2009
Object-in-place memory, which relies on the formation of associations between an object and the place in which it was encountered, depends upon a neural circuit comprising the perirhinal (PRH) and medial prefrontal (mPFC) cortices.
Warburton, Elizabeth C, Barker, GRI
core   +1 more source

Evaluation of Different Combined Regimens in the Treatment of Cholinergic Urticaria

open access: yesWorld Allergy Organization Journal, 2012
Background Cholinergic urticaria is uncommon and accounts for 10% of all young adults. To date, there is no effective therapy for cholinergic urticaria.Objective To determine the therapeutic efficacy of different drug combinations in the treatment of ...
Abdulghani M. Alsamarai, MD, PhD   +2 more
doaj   +1 more source

Inflammation Regulation via an Agonist and Antagonists of α7 Nicotinic Acetylcholine Receptors in RAW264.7 Macrophages

open access: yesMarine Drugs, 2022
The α7 nicotinic acetylcholine receptor (nAChR) is widely distributed in the central and peripheral nervous systems and is closely related to a variety of nervous system diseases and inflammatory responses.
Yao Tan   +5 more
doaj   +1 more source

Otorhinolaryngological adverse effects of urological drugs

open access: yesInternational Brazilian Journal of Urology, 2021
Purpose: To describe the otorhinolaryngological adverse effects of the main drugs used in urological practice. Materials and Methods: A review of the scientific literature was performed using a combination of specific descriptors (side effect, adverse ...
Nathalia de Paula Doyle Maia   +2 more
doaj   +1 more source

The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine [PDF]

open access: yes, 2014
Background: The main source of 5-HT in body is in enterchromafin cells of intestine, different studies mentioned different roles for endogenous 5-HT and receptors involved and it is not clearified the mechanism of action of endogenous 5-HT. Objectives:
Javid, Farideh A.   +2 more
core   +5 more sources

Basic and Clinical Aspects of Non-neuronal Acetylcholine: Expression of Non-neuronal Acetylcholine in Lung Cancer Provides a New Target for Cancer

open access: yesJournal of Pharmacological Sciences, 2008
Lung cancer is the leading cause of cancer death worldwide and new treatment strategies are clearly needed. The recent discovery that lung and other cancers synthesize and secrete acetylcholine (ACh) which acts as an autocrine growth factor suggests that
Therapy Pingfang Song, Eliot R. Spindel
doaj   +1 more source

Exploring Cholinergic Compounds for Peripheral Neuropathic Pain Management: A Comprehensive Scoping Review of Rodent Model Studies

open access: yesPharmaceuticals, 2023
Neuropathic pain affects about 7–8% of the population, and its management still poses challenges with unmet needs. Over the past decades, researchers have explored the cholinergic system (muscarinic and nicotinic acetylcholine receptors: mAChR and nAChR)
Edouard Montigné, David Balayssac
doaj   +1 more source

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