Results 21 to 30 of about 746,801 (362)

A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]

open access: yes, 2004
An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, JC   +5 more
core   +5 more sources

Oxybutynin as an alternative treatment for hyperhidrosis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
: Hyperhidrosis is the excessive production of sweating, which can be primary and focal or secondary to various pathologies. The exact cause of primary focal hyperhidrosis is still unknown, although a genetic basis is recognized, and its prevalence ...
Sergio Delort   +2 more
doaj   +1 more source

Efficacy of Anticholinergics for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Young and Middle-Aged Patients: A Single-Blinded, Prospective, Multi-Center Study [PDF]

open access: yesInternational Neurourology Journal, 2011
Purpose Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) exhibits variable lower urinary tract symptoms (LUTS). The aim of this study was to evaluate the incidence of LUTS and the efficacy of an anticholinergic agent in young and middle-aged CP/
Doo Sang Kim   +4 more
doaj   +1 more source

Frequency-specific modulation of oscillatory activity in the rat auditory cortex by vagus nerve stimulation

open access: yesBrain Stimulation, 2023
Background: We previously found that vagus nerve stimulation (VNS) strengthened stimulus-evoked activity in the superficial layer of the sensory cortex but not in the deep layer, suggesting that VNS altered the balance between the feedforward (FF) and ...
Shinichi Kumagai   +7 more
doaj   +1 more source

Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors.

open access: yesPLoS ONE, 2021
Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic ...
Olha Zapukhliak   +7 more
doaj   +1 more source

Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? [PDF]

open access: yes, 2014
The authors acknowledge the medical writing assistance received from Sam Yarwood, PhD, of Complete HealthVizion, in the form of literature searches and preparation and revision of the draft manuscript.Peer reviewedPublisher ...
Fromer, Leonard   +4 more
core   +7 more sources

Differential pharmacological and sex-specific effects of antimuscarinic agents at the hypoglossal motor nucleus in vivo in rats

open access: yesScientific Reports, 2022
Successful cholinergic-noradrenergic pharmacotherapy for obstructive sleep apnea (OSA) is thought to be due to effects at the hypoglossal motor nucleus (HMN). Clinical efficacy varies with muscarinic-receptor (MR) subtype affinities. We hypothesized that
Sepehr Niakani   +3 more
doaj   +1 more source

Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?

open access: yesFrontiers in Pharmacology, 2021
Social species form organizations that support individuals because the consequent social behaviors help these organisms survive. The isolation of these individuals may be a stressor. We reviewed the potential mechanisms of the effects of social isolation
Jaromir Myslivecek
doaj   +1 more source

Cholinergic Mechanisms in Spinal Locomotion - Potential Target for Rehabilitation Approaches

open access: yesFrontiers in Neural Circuits, 2014
Previous experiments implicate cholinergic brainstem and spinal systems in the control of locomotion. Our results demonstrate that the endogenous cholinergic propriospinal system, acting via M2 and M3 muscarinic receptors, is capable of consistently ...
L M Jordan   +9 more
doaj   +1 more source

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