Results 21 to 30 of about 31,317 (345)

Oxybutynin as an alternative treatment for hyperhidrosis [PDF]

Anais Brasileiros de Dermatologia, 2017
: Hyperhidrosis is the excessive production of sweating, which can be primary and focal or secondary to various pathologies. The exact cause of primary focal hyperhidrosis is still unknown, although a genetic basis is recognized, and its prevalence ...
Sergio Delort, Evaldo Marchi, Marcos Antônio Corrêa   +2 more
doaj   +1 more source

Efficacy of Anticholinergics for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Young and Middle-Aged Patients: A Single-Blinded, Prospective, Multi-Center Study [PDF]

International Neurourology Journal, 2011
Purpose Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) exhibits variable lower urinary tract symptoms (LUTS). The aim of this study was to evaluate the incidence of LUTS and the efficacy of an anticholinergic agent in young and middle-aged CP/
Doo Sang Kim, Yoon Soo Kyung, Seung Hyo Woo, Young Seop Chang, Hyung-Jee Kim   +4 more
doaj   +1 more source

Frequency-specific modulation of oscillatory activity in the rat auditory cortex by vagus nerve stimulation

Brain Stimulation, 2023
Background: We previously found that vagus nerve stimulation (VNS) strengthened stimulus-evoked activity in the superficial layer of the sensory cortex but not in the deep layer, suggesting that VNS altered the balance between the feedforward (FF) and ...
Shinichi Kumagai, Tomoyo Isoguchi Shiramatsu, Akane Matsumura, Yohei Ishishita, Kenji Ibayashi, Yoshiyuki Onuki, Kensuke Kawai, Hirokazu Takahashi   +7 more
doaj   +1 more source

Effects of vasoactive intestinal polypeptide antagonists on cholinergic neurotransmission in dog and cat trachea [PDF]

British Journal of Pharmacology, 1991
Takuo Hirose, Yoshihiro Itô
exaly   +2 more sources

Mecamylamine inhibits seizure-like activity in CA1-CA3 hippocampus through antagonism to nicotinic receptors.

PLoS ONE, 2021
Cholinergic modulation of hippocampal network function is implicated in multiple behavioral and cognitive states. Activation of nicotinic and muscarinic acetylcholine receptors affects neuronal excitability, synaptic transmission and rhythmic ...
Olha Zapukhliak, Olga Netsyk, Artur Romanov, Oleksandr Maximyuk, Murat Oz, Gregory L Holmes, Oleg Krishtal, Dmytro Isaev   +7 more
doaj   +1 more source

Differential pharmacological and sex-specific effects of antimuscarinic agents at the hypoglossal motor nucleus in vivo in rats

Scientific Reports, 2022
Successful cholinergic-noradrenergic pharmacotherapy for obstructive sleep apnea (OSA) is thought to be due to effects at the hypoglossal motor nucleus (HMN). Clinical efficacy varies with muscarinic-receptor (MR) subtype affinities. We hypothesized that
Sepehr Niakani, Hattie Liu, Wen-Ying Liu, Richard L. Horner   +3 more
doaj   +1 more source

Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?

Frontiers in Pharmacology, 2021
Social species form organizations that support individuals because the consequent social behaviors help these organisms survive. The isolation of these individuals may be a stressor. We reviewed the potential mechanisms of the effects of social isolation
Jaromir Myslivecek
doaj   +1 more source

Unlocking new mechanisms for future ALS therapies: early interventions with cholinergic antagonists reduce neuromuscular decline [PDF]

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition characterized by motor neuron loss, leading to muscle paralysis and death. C-boutons have been shown to be part of the compensatory mechanism behind delayed symptom onset, and are most ...
Reynaldo Popoli, Tyler L. Wells, Turgay Akay   +2 more
openalex   +2 more sources

Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]

, 2011
The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Brown, MW, Warburton, E Clea, Endean, E. P. E., Fontaine-Palmer, N. S., Chris J. Tinsley, Endean, Emma P E, Aggleton, John P, Tinsley, CJ, John P. Aggleton, Emma P.E. Endean, Vincent, Maria, Aggleton, John Patrick, Endean, EPE, Maria Vincent, E. Clea Warburton, Nadine S. Fontaine-Palmer, Brown, M. W., Malcolm W. Brown, Tinsley, Chris J, Brown, Malcolm W, Vincent, M., Fontaine-Palmer, NS, Tinsley, C. J., Vincent, M, Fontaine-Palmer, Nadine S, Aggleton, JP, Warburton, EC, Warburton, E. C.   +27 more
core   +1 more source

Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease [PDF]

, 2015
Background Patients with advanced Parkinson's disease (PD) often present with axial symptoms, including postural- and gait difficulties that respond poorly to dopaminergic agents.
Pienaar, Ilse, De Paola, V, Gretenkord, Sabine, David Dexter (3572210), Sabine Gretenkord, Withers, Dominic, Ilse Pienaar (4504357), Dominic Withers (3572216), Gartside, Sarah, De Paola, Vincenzo, Puneet Sharma, Ilse S. Pienaar, Puneet Sharma (3572222), Sharma, Puneet, Dominic Withers, Sabine Gretenkord (3572213), David T. Dexter, Vincenzo De Paola, Joanna L. Elson, Ilse Pienaar (3572219), Joanna L Elson (16036517), Sarah Gartside (3572225), Dexter, David, Elson, Joanna, Sarah E. Gartside, Joanna Elson (271089), Vincenzo De Paola (275215), Sarah E Gartside (16264538), David T Dexter (9237410)   +28 more
core   +1 more source