Results 141 to 150 of about 29,437 (244)

Restoring Septohippocampal Cholinergic Signaling Rescues Surgery‐Induced Neurogenesis and Memory Deficits in Aged Mice

Aging Cell, Volume 25, Issue 6, June 2026.
Surgery‐induced MS/vDB → DG cholinergic decline impairs hippocampal neurogenesis and memory in aged mice; galantamine‐mediated cholinergic potentiation or sustained chemogenetic activation rescues these deficits, highlighting therapeutic potential for POCD.
Lei Lei, Qingsheng Meng, Xiaoyu Hu, Jinjin Yang, Ni Du, Songxue Su, Kenji Hashimoto, Jing Cao, Jian‐jun Yang   +8 more
wiley   +1 more source

Cholinergic interneurons control the excitatory input to the striatum

, 2007
How the extent and time course of presynaptic inhibition depend on the action potentials of the neuron controlling the terminals is unknown. We investigated this issue in the striatum using paired recordings from cholinergic interneurons and projection ...
Bracci, Enrico, Pakhotin, Pavel
core   +1 more source

Fentanyl Compromises Lower‐Airway Mechanics and Naloxone Triggers a Transient Mechanical Overshoot

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Opioid‐induced respiratory depression (OIRD) is the leading cause of death following opioid overdose, due to its effects on central rhythm generation, and airway and thoracic constriction. While the effects on rhythm generation have been well documented, the effects of fentanyl on airway constriction are less well understood. We tested the
Riley R. Parks, Marissa J. Andersen, Mackenna L. Hatfield, Madeline M. Johnson, Nicholas J. Burgraff   +4 more
wiley   +1 more source

Cholinergic modulation of neurofilament expression and neurite outgrowth in chick sensory neurons

, 2003
The morphogenetic role of the neurotransmitter acetylcholine was studied in cultures of dorsal root ganglia (DRG) neurons obtained from E12 and E18 chick embryos.
BIAGIONI, Stefano, TOCCO, Gabriella, Silvia Cursi, TATA, Ada Maria   +3 more
core   +1 more source

tVNS Mitigates Neuroinflammation and Nociception in a Rodent LPS Endotoxemia Model

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Experimental design and key findings. Four groups (Control+Sham, Control+tVNS, LPS+Sham, LPS+tVNS; n = 7 each) underwent serum ELISA, brain Western blot, and behavioral testing. tVNS altered serum Haptoglobin, IL‐6, CGRP1, and VE‐Cadherin levels, reversed LPS‐induced increases in brain IL‐1β, HMGB1, Haptoglobin, PAR‐2, and CGRP, and alleviated LPS ...
Kerem Atalar, Ece Alim, Aysen Calikusu, Elif Gulcicek Abbasoglu Topa, Hale Gok Dagidir, Meltem Bahcelioglu, Neslihan Bukan, Fusun Erten, Kazım Sahin, Saadet Özen Akarca Dizakar, Hayrunnisa Bolay   +10 more
wiley   +1 more source

Evidence of muscarinic acetylcholine receptors in the retinal centrifugal system of the chick

Brazilian Journal of Medical and Biological Research, 2000
In this study we characterize the presence of muscarinic acetylcholine receptors (mAChR) in the isthmo-optic nucleus (ION) of chicks by immunohistochemistry with the M35 antibody.
Calaza K.C., Gardino P.F.
doaj  

Three‐year outcomes of repeated botulinum neurotoxin A injections to the lower extremities in young children with spastic cerebral palsy in GMFCS levels I to III

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 792-799, June 2026.
In this study, we followed a group of children 2 to 6 years old with spastic cerebral palsy functioning in GMFCS levels I–III, over 3 years. Sixty‐five received BoNT‐A and 59 did not. Repeated BoNT‐A injections over 3 years were not associated with improvements in gross motor function or passive ankle dorsiflexion. Daily step counts, favouring the BoNT‐
Darcy Fehlings, Emma Bohn, Lauren Switzer, Charles H. Goldsmith, Unni Narayanan, Peter L. Rosenbaum, F. Virginia Wright, Gary Foster, CP‐BoNT‐A Study Group, Timothy Carey, Mark Mason, Ronit Mesterman   +11 more
wiley   +1 more source

Deep Brain Stimulation of the Nucleus Accumbens Modulates Effort‐Based Decision‐Making and Phasic Dopamine Release in Male Wistar Rats

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
The release of mesolimbic dopamine (DA) within the nucleus accumbens (NAc) underpins several critical behaviours. In this study, we observed how high‐frequency deep brain stimulation of the NAc modulated motivational behaviour and local neurodynamics within male Wistar rats.
Sebastian McCullough, Roger B. Varela, Tristan Houghton, Heather Cruickshank, Susannah J. Tye   +4 more
wiley   +1 more source

Lateral hypothalamic melanin concentrating hormone‐expressing neurons both promote and are required for cue‐potentiated feeding

Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Food‐related stimuli can promote feeding behaviors independent of metabolic need. Cue‐potentiated feeding (CPF) studies in rodents offer the potential to reveal the psychobiological mechanisms underlying learned overeating behaviors. We examined whether lateral hypothalamic area (LHA) cells expressing the feeding signal Melanin Concentrating ...
Lauren M. Raycraft, Bingxin Mo, Allison Doneth, Jenna Lee‐Tanner, Alexander W. Johnson   +4 more
wiley   +1 more source

Autonomic Nervous System Phenotyping Across Chronic Demyelinating Peripheral Neuropathies: A Comparative Study

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims This study aimed to systematically phenotype autonomic nervous system (ANS) involvement in patients with chronic inflammatory demyelinating polyneuropathy (CIDP), monoclonal gammopathy of undetermined significance‐associated neuropathy (MGUS‐PNP), Charcot–Marie–Tooth disease Type 1A (CMT1A), and hereditary neuropathy with ...
Bogdan Bjelica, Teodora Todorovic, Ivo Bozovic, Aleksa Palibrk, Vladimir Jankovic, Ivana Basta, Stojan Peric   +6 more
wiley   +1 more source