Results 11 to 20 of about 1,448,122 (321)

Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain

open access: yeseLife, 2020
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway   +7 more
doaj   +2 more sources

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost Cyprinus carpio [PDF]

open access: yesEuropean Journal of Histochemistry, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Arianna Casini   +3 more
doaj   +4 more sources

Elevated Levels of miR-144-3p Induce Cholinergic Degeneration by Impairing the Maturation of NGF in Alzheimer’s Disease

open access: yesFrontiers in Cell and Developmental Biology, 2021
Cholinergic degeneration is one of the key pathological hallmarks of Alzheimer’s disease (AD), a condition that is characterized by synaptic disorders and memory impairments. Nerve growth factor (NGF) is secreted in brain regions that receive projections
Lan-Ting Zhou   +16 more
doaj   +2 more sources

Cholinergic fiber aberrations in nucleus basalis lesioned rat and Alzheimer's disease [PDF]

open access: greenNeurobiology of Aging, 1992
Innervation density and morphological aberrations of cholinergic fibers were studied with choline acetyltransferase (ChAT) immunocytochemistry and acetylcholinesterase (AChE) histochemistry in 30-35 month-old aged rats and rats with long-term bilateral lesions of the magnocellular basal nucleus (MBN).
Ronald P. Gaykema   +5 more
openalex   +6 more sources

A part of cholinergic fibers in mouse superior cervical ganglia contain GABA or glutamate [PDF]

open access: greenBrain Research, 2005
The localizations and functions of glutamate and GABA, the major amino acid neurotransmitters in the central nervous system, are still unclear in the peripheral nervous system. We immunohistochemically double-stained mouse superior cervical ganglia with antibodies for the vesicular acetylcholine transporter (VAchT), GAD65, the vesicular glutamate ...
Tetsufumi Ito   +2 more
openalex   +4 more sources

Tractography of the external capsule and cognition: A diffusion MRI study of cholinergic fibers

open access: yesExperimental Gerontology, 2019
White matter changes (WMC) in the cholinergic tracts contribute to executive dysfunction in the context of cognitive aging. WMC in the external capsule have been associated with executive dysfunction. The objectives of this study were to: 1) Characterize the lateral cholinergic tracts (LCT) and the superior longitudinal fasciculus (SLF).
Geneviève Nolze-Charron   +9 more
semanticscholar   +4 more sources

Effects of Field Stimulation on Cholinergic Fibers of the Pelvic Region in the Isolated Guinea Pig Ureter

open access: bronzeThe Japanese Journal of Physiology, 1980
Electrical activities have been recorded in a preparation consisting of the pelvic region and the upper ureter of the guinea pig. Train field stimulation of the pelvic region evoked a train of nerve action potentials followed by a multiphasic smooth ...
Soichi Yoshida, Tetsurō Kuga
openalex   +3 more sources

Synaptic-like axo-axonal transmission from striatal cholinergic interneurons onto dopaminergic fibers [PDF]

open access: hybridNeuron, 2022
P. Kramer   +8 more
openalex   +2 more sources

Cholinergic Signaling Attenuates Pro-Inflammatory Interleukin-8 Response in Colonic Epithelial Cells

open access: yesFrontiers in Immunology, 2022
Infants affected by Hirschsprung disease (HSCR), a neurodevelopmental congenital disorder, lack ganglia of the intrinsic enteric nervous system (aganglionosis) in a variable length of the colon, and are prone to developing severe Hirschsprung-associated ...
Isabelle Müller   +23 more
doaj   +2 more sources

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

open access: yesFrontiers in Aging Neuroscience, 2019
Increasing evidence supports a role for cerebrovasculature dysfunction in the etiology of Alzheimer’s disease (AD). Blood vessels in the brain are composed of a collection of cells and acellular material that comprise the neurovascular unit (NVU).
Shereen Nizari   +3 more
doaj   +2 more sources

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