Relationship Between Plaques, Tangles, and Loss of Cortical Cholinergic Fibers in Alzheimer Disease [PDF]
Recent observations in our laboratory have indicated substantial and systematic regional variations in the loss of cortical cholinergic fibers in Alzheimer disease (AD). Previous attempts to study the relationship between cortical cholinergic loss and the density of cortical pathological lesions have resulted in conflicting findings.
C, Geula +3 more
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Systematic Regional Variations in the Loss of Cortical Cholinergic Fibers in Alzheimer's Disease [PDF]
The loss of cortical cholinergic fibers in Alzheimer's disease was investigated using choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Within both the normal and Alzheimer's cerebral cortex, the two methods revealed an identical pattern of fiber staining.
C, Geula, M M, Mesulam
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Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain
The basal forebrain cholinergic system projects broadly throughout the cortex and constitutes a critical source of neuromodulation for arousal and attention. Traditionally, this system was thought to function diffusely.
Kathryn C Allaway +7 more
doaj +2 more sources
Pegylated Insulin-Like Growth Factor 1 attenuates Hair Cell Loss and promotes Presynaptic Maintenance of Medial Olivocochlear Cholinergic Fibers in the Cochlea of the Progressive Motor Neuropathy Mouse. [PDF]
Bieniussa L +7 more
europepmc +3 more sources
Functional separation of adrenergic and cholinergic fibers to skeletal muscle vessels
The hypothesis that sympathetic innervation to skeletal muscle vasculature contains functionally distinct adrenergic and cholinergic fibers was investigated utilizing the dog isolated perfused gracilis muscle. The use of hemicholinium in an attempt to abolish cholinergic dilatation, but not adrenergic constriction, in response to intermittent nerve ...
L D, DORR, M J, BRODY
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Cholinergic Signaling Attenuates Pro-Inflammatory Interleukin-8 Response in Colonic Epithelial Cells
Infants affected by Hirschsprung disease (HSCR), a neurodevelopmental congenital disorder, lack ganglia of the intrinsic enteric nervous system (aganglionosis) in a variable length of the colon, and are prone to developing severe Hirschsprung-associated ...
Isabelle Müller +23 more
doaj +2 more sources
Synergistic action of serotoninergic and cholinergic fibers resulted in augmented vagus heart deceleration when stellate ganglion stimulation was added to vagus nerve stimulation.
A. E. Lychkova, V. M. Smirnov
doaj +1 more source
Aspiration removal of orbitofrontal cortex disrupts cholinergic fibers of passage to anterior cingulate cortex in rhesus macaques. [PDF]
Eldridge MAG +4 more
europepmc +3 more sources

