Results 141 to 150 of about 50,388 (308)

The development of hepatic steatosis depends on the presence of liver-innervating parasympathetic cholinergic neurons in mice fed a high-fat diet [PDF]

, 2023
Jiyeon Hwang, Junichi Okada, Liu Li, Jeffrey E. Pessin, Gary J. Schwartz, Young‐Hwan Jo   +5 more
openalex   +1 more source

Sleep Slow Wave‐Bistability and the Connection Between the Sleeping Brain and the Environment—Neurobiological Considerations

Journal of Sleep Research, EarlyView.
Bistability is an inherent working mode of NREM sleep. Those bistable patterns ‐ sleep slow waves, K‐complexes, and the cyclic alternating pattern (on a longer, several seconds' time‐scale) ‐ have a double function; they protect sleep and provide an interface between the brain and the environment for information‐transfer during sleep.
Péter Halász, Anna Szűcs, Carlotta Mutti, Liborio Parrino   +3 more
wiley   +1 more source

A role for the cholinergic neuron circadian clock in RNA metabolism and mediating neurodegeneration. [PDF]

Life Sci Alliance
Tam SB, Waldeck NJ, Wright M, Mojsilovic-Petrovic J, Baker EM, Kiskinis E, Bass J, Kalb RG.   +7 more
europepmc   +1 more source

The cell adhesion molecule L1 regulates the expression of choline acetyltransferase and the development of septal cholinergic neurons [PDF]

, 2011
Xuezhi Cui, Yingqi Weng, Isabelle Frappé, Alison Burgess, M. Teresa Girão da Cruz, Melitta Schachner, Isabelle Aubert   +6 more
openalex   +1 more source

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

Neurogastroenterology &Motility, EarlyView.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz, Hassler Bueno Garcia, Andrew S. Perley, Todd P. Coleman, Julia A. Kaltschmidt   +4 more
wiley   +1 more source

Cholinergic neuron-to-glioblastoma synapses in a human iPSC-derived co-culture model. [PDF]

Stem Cell Reports
Sun Y, Wang X, Zhang Z, Park KH, Wu Y, Dong W, Zhang DY, Fu Y, Zhang F, Binder ZA, Ling-Lin Pai E, Nasrallah MP, Christian KM, O'Rourke DM, Toni N, Ming GL, Song H.   +16 more
europepmc   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source

BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system

The Journal of Clinical Investigation
Epigenetic regulatory mechanisms are underappreciated, yet are critical for enteric nervous system (ENS) development and maintenance. We discovered that fetal loss of the epigenetic regulator Bap1 in the ENS lineage caused severe postnatal bowel ...
Sabine Schneider, Jessica B. Anderson, Rebecca P. Bradley, Katherine Beigel, Christina M. Wright, Beth A. Maguire, Guang Yan, Deanne M. Taylor, J. William Harbour, Robert O. Heuckeroth   +9 more
doaj   +1 more source

Genetic Implication of Prenatal GABAergic and Cholinergic Neuron Development in Susceptibility to Schizophrenia. [PDF]

Schizophr Bull
Cameron D, Vinh NN, Prapaiwongs P, Perry EA, Walters JTR, Li M, O'Donovan MC, Bray NJ.   +7 more
europepmc   +1 more source

A cell autonomous torsinA requirement for cholinergic neuron survival and motor control. [PDF]

Elife, 2018
Pappas SS, Li J, LeWitt TM, Kim JK, Monani UR, Dauer WT.   +5 more
europepmc   +1 more source