The following article for this Special Issue was previously published and can be found in its respective issue online: “Long‐term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis” [PDF]
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The Ontogenetic Development of Rapid Eye Movement Sleep in Early Life and Its Regulatory Mechanisms
International Journal of Developmental Neuroscience, Volume 86, Issue 1, February 2026.REM sleep was first identified in humans and cats in the late 1950s and exhibits a conserved developmental trajectory across species. This study elucidates key characteristic changes during REM sleep development, thereby providing a foundation for improving the prevention and treatment of various neurodevelopmental disorders.
Xiu‐Juan Zhang +8 more
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Data-driven modeling of cholinergic modulation of neural microcircuits: bridging neurons, synapses, and network states [PDF]
, 2018 Srikanth Ramaswamy, Henry Markram
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MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
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Simultaneous Release of Glutamate and Acetylcholine from Single Magnocellular “Cholinergic” Basal Forebrain Neurons [PDF]
, 2006 T.G.J. Allen +2 more
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Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
MedComm, Volume 7, Issue 2, February 2026.The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
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Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss
Aging Cell, Volume 25, Issue 2, February 2026.Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli +3 more
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