Results 11 to 20 of about 50,388 (308)

Loss of Basal Forebrain Cholinergic Neurons Following Adolescent Binge Ethanol Exposure: Recovery With the Cholinesterase Inhibitor Galantamine

open access: yesFrontiers in Behavioral Neuroscience, 2021
Binge drinking and alcohol abuse are common during adolescence and cause both cognitive deficits and lasting cholinergic pathology in the adult basal forebrain.
Fulton T. Crews   +5 more
doaj   +1 more source

Cholinergic Neuronal Deficits in CADASIL [PDF]

open access: yesStroke, 2007
Background and Purpose— Previous evidence from MRI and acetylcholinesterase histochemistry suggests cholinergic fibers are affected in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Methods—
Jessica S, Keverne   +5 more
openaire   +2 more sources

Medial and dorsal lateral septum involving social disruption stress-primed escalation in acid-induced writhes

open access: yesFrontiers in Molecular Neuroscience, 2023
IntroductionStress may cause prospective escalations in abdominal pain magnitude and accumbal TRPV1 expression, while central neural circuits mediating these stress effects remain unclear.MethodsUsing retrograde tracing methods, we first demonstrated the
Yi-Han Liao   +7 more
doaj   +1 more source

Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway

open access: yesActa Pharmaceutica Sinica B, 2023
Both cholinergic dysfunction and protein citrullination are the hallmarks of rheumatoid arthritis (RA), but the relationship between the two phenomena remains unclear. We explored whether and how cholinergic dysfunction accelerates protein citrullination
Changjun Lv   +12 more
doaj   +1 more source

Human Mesenchymal Stem Cells Seeded on the Natural Membrane to Neurospheres for Cholinergic-like Neurons

open access: yesMembranes, 2021
This study aimed to differentiate human mesenchymal stem cells (hMSCs) from the human umbilical cord in cholinergic-like neurons using a natural membrane.
Priscila Elias Ferreira Stricker   +11 more
doaj   +1 more source

Acetylcholine and spinal locomotor networks: The insider

open access: yesPhysiological Reports, 2021
This article aims to review studies that have investigated the role of neurons that use the transmitter acetylcholine (ACh) in controlling the operation of locomotor neural networks within the spinal cord. This cholinergic system has the particularity of
Théo Mille   +3 more
doaj   +1 more source

Cholinergic Neuron-Like Cells Derived from Bone Marrow Stromal Cells Induced by Tricyclodecane-9-yl-Xanthogenate Promote Functional Recovery and Neural Protection after Spinal Cord Injury

open access: yesCell Transplantation, 2013
The rate of neuronal differentiation of bone marrow stromal cells (BMSCs) in vivo is very low; therefore, it is necessary to elevate the number of BMSC-derived neurons to cure neurodegenerative diseases.
Chunhui Sun   +8 more
doaj   +1 more source

Selective Activation of Cholinergic Interneurons Enhances Accumbal Phasic Dopamine Release: Setting the Tone for Reward Processing

open access: yesCell Reports, 2012
Dopamine plays a critical role in motor control, addiction, and reward-seeking behaviors, and its release dynamics have traditionally been linked to changes in midbrain dopamine neuron activity.
Roger Cachope   +7 more
doaj   +1 more source

Single-Cell Gene Expression Analysis of Cholinergic Neurons in the Arcuate Nucleus of the Hypothalamus. [PDF]

open access: yesPLoS ONE, 2016
The cholinoceptive system in the hypothalamus, in particular in the arcuate nucleus (ARC), plays a role in regulating food intake. Neurons in the ARC contain multiple neuropeptides, amines, and neurotransmitters.
Jae Hoon Jeong   +3 more
doaj   +1 more source

Simultaneous Acquisition of Multicolor Information From Neural Circuits in Resin-Embedded Samples

open access: yesFrontiers in Neuroscience, 2018
Resin embedding has been widely used for precise imaging of fluorescently labeled biological samples with optical and electron microscopy. The low preservation rate of fluorescence, especially for red fluorescent proteins, has limited the application of ...
Miao Ren   +14 more
doaj   +1 more source

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