Results 221 to 230 of about 50,388 (308)

Cortically Dependent Motor Training Does Not Induce Abnormal Movements in DYT1‐Knock In Mice

Brain and Behavior, Volume 16, Issue 1, January 2026.
DYT1 dystonia is a familial autosomal dominant, childhood onset dystonia. Mouse models recapitulating the human genotype do not exhibit overtly dystonic movements. It is unclear whether cortically‐dependent tasks are necessary for the development of dystonic movements.
Alexander T. Hodge, Mohammed A. Rasheed, Tiffany Lin, Christian R. Burgess, Daniel K. Leventhal   +4 more
wiley   +1 more source

Cholinergic suppression of heart rate acceleration during intrinsic optogenetic activation of sympathetic cardiac neurons in perfused hearts. [PDF]

Am J Physiol Heart Circ Physiol
Russo R, Moreno A, Dwyer MK, Skancke M, Trachiotis G, Mendelowitz D, Kay MW.   +6 more
europepmc   +1 more source

Exploring Adjunctive Novel Therapeutic Approach of KarXT (Xanomeline‐Trospium Chloride) for Managing Psychotic Symptoms in Patients With Schizophrenia and Alzheimer's Disease

Brain and Behavior, Volume 16, Issue 1, January 2026.
An overview of the mechanism of action, clinical trials, and classical findings of KarXT for the management of psychotic symptoms in patients with schizophrenia and alzheimer's disease. ABSTRACT Background Acute psychotic symptoms like delusions and hallucinations are of major concern while treating patients with schizophrenia and alzheimer's psychosis,
Ashir Kanwal, Bismah Azeem, Hania Nasir, Fatima Mumtaz, Nauman Ashraf, Mohammed Hammad Jaber Amin, Warisha Kanwal, Bilal Wazir Khan   +7 more
wiley   +1 more source

Subcortical Brain‐Age Gaps Reveal Asymmetric Aging Patterns in Parkinson's Disease With Cognitive Impairment

Brain and Behavior, Volume 16, Issue 1, January 2026.
Accelerated brain aging in Parkinson's disease is not global but a localized, asymmetric process in the left limbic‐cholinergic network. Regional brain‐age metrics offer a sensitive biomarker for detecting the specific neurodegeneration linked to cognitive decline.
Sadegh Ghaderi, Ali Fathi Jouzdani, Ali Mohammad Pourbagher‐Shahri, Sana Mohammadi   +3 more
wiley   +1 more source

A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Sujan Tamang, Bishwo Ram Amatya, Sulav Neupane, Sunischit Chandra Neupane, Chiranjivi Panta, Anusmriti Pal, Dipesh Shrestha   +6 more
wiley   +1 more source

Enteric glial S100B controls rhythmic colonic functions by regulating excitability and specificity in gut motor neurocircuits. [PDF]

J Physiol
Thomasi B, Lavalle R, McClain JL, Jamka J, Seguella L, Gulbransen BD.   +5 more
europepmc   +1 more source

Altered Functional Specialization and Interhemispheric Coordination in Rhegmatogenous Retinal Detachment: Associations With Gene Expression, Neurotransmitter Receptor Distribution, and SVM–SHAP Classification

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Autonomy Index (AI) and Connective Flexibility of Homotopic voxels (CFH) were derived from resting‐state fMRI data following standard preprocessing. These functional metrics were computed based on the AAL90 atlas to characterize intrinsic activity and interhemispheric coordination patterns in RRD patients.
Yu Ji, Yuan‐Yuan Wang, Xiao‐Rong Wu
wiley   +1 more source

Brain atrophy and cholinergic denervation in progressive supranuclear palsy: an MRI and [¹⁸F]-FEOBV PET study. [PDF]

Front Neurosci
Kanel P, Roytman S, Carli G, Vangel R, Barr J, Michalakis F, Spears CC, Scott PJH, Albin RL, Bohnen NI.   +9 more
europepmc   +1 more source

NLP-9 is released from cholinergic neurons in a cAMP-dependent manner.

Jiajie Shao (1729147), Jana F. Liewald (21273553), Wagner Steuer Costa (6813063), Christiane Ruse (21273556), Jens Gruber (4019942), Mohammad S. Djamshedzad (21273559), Wulf Gebhardt (21273562), Alexander Gottschalk (129613)   +7 more
openalex   +1 more source

Lineage‐Biased Neural Stem Cell Grafting Promotes Neuronal Differentiation and Vascular Repair in the Chronic Phase of Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Schematic diagram comparing two differentiation strategies to generate NSCs. The nEB‐NSCs exhibited a pronounced bias toward neuronal lineage differentiation. Transplantation of nEB‐NSCs into stroke mice (induced by tMCAO surgery) promoted motor recovery and vascular repair.
Tingting Zhang, Da Li, Qibiao Guan, Bin An, Yun Sun, Qiang Wang, Yukai Wang, Baoyang Hu   +7 more
wiley   +1 more source