Results 141 to 150 of about 85,202 (263)

Establishing a 3D Spheroid Model of Cholinergic Neurons from SH-SY5Y Cells for Neurotoxicity Assessment. [PDF]

Toxins (Basel)
Franco-Campos F, Fernández-Franzón M, Rodríguez-Carrasco Y, Ruiz MJ.   +3 more
europepmc   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Projections from ventral hippocampus to nucleus accumbens' cholinergic neurons are altered in depression. [PDF]

J Gen Physiol
Medrihan L, Knudsen MG, Ferraro T, Del Cioppo Vasques P, Romin Y, Fujisawa S, Greengard P, Milosevic A.   +7 more
europepmc   +1 more source

Feed-forward metabotropic signaling by Cav1 Ca²⁺ channels supports pacemaking in pedunculopontine cholinergic neurons. [PDF]

Neurobiol Dis, 2023
Tubert C, Zampese E, Pancani T, Tkatch T, Surmeier DJ.   +4 more
europepmc   +1 more source

Dreaming conundrum

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti, Francesca Siclari, Ivana Rosenzweig   +2 more
wiley   +1 more source

The primary cilium of cholinergic neurons may be a linchpin in the progression of Parkinson's Disease. [PDF]

Proc Natl Acad Sci U S A
Uribe-Cano S, Kottmann AH.
europepmc   +1 more source

Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR. [PDF]

eNeuro, 2023
Dasgupta S, Montroull LE, Pandya MA, Zanin JP, Wang W, Wu Z, Friedman WJ.   +6 more
europepmc   +1 more source

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin, Kinga Igloi, Alison Montagrin, Samika Kumar, Jeremy Hofmeister, Markus Gschwind, Sophie Schwartz, Virginie Sterpenich   +7 more
wiley   +1 more source

Benefits of Maternal Choline Supplementation on Aged Basal Forebrain Cholinergic Neurons (BFCNs) in a Mouse Model of Down Syndrome and Alzheimer's Disease. [PDF]

Biomolecules
Alldred MJ, Pidikiti H, Ibrahim KW, Lee SH, Heguy A, Chiosis G, Mufson EJ, Stutzmann GE, Ginsberg SD.   +8 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source