Results 241 to 250 of about 2,475,404 (303)

Additive effects of mirabegron on muscarinic receptor binding and on relaxation of cholinergic detrusor muscle contraction by antimuscarinics

Shizuo Yamada, Masae Mochizuki, Kana Maruyama‐Fumoto, Satomi Kagota, Kazumasa Shinozuka   +4 more
openalex   +1 more source

Dual cholinergic and serotonergic excitatory pathways mediate oxygen sensing in the zebrafish gill

The Journal of Physiology, EarlyView.
Abstract figure legend The present study identified two sub‐populations of gill oxygen sensing neuroepithelial cells (NECs) distinguishable by their stored neurotransmitters – serotonin (5‐hydroxytryptamine, 5‐HT) or acetylcholine (ACh). Using transgenic Tg(elavl3:GCaMP6s) zebrafish, which express an endogenous calcium reporter in neurons, we ...
Maddison Reed, Anthea A. Mavridis, Jan A. Mennigen, Michael G. Jonz   +3 more
wiley   +1 more source

Acetylcholine in the hippocampus: problems and achievements. [PDF]

Front Neural Circuits
Dobryakova YV, Bolshakov AP, Korotkova T, Rozov AV.   +3 more
europepmc   +1 more source

Intrinsic mechanisms contributing to the biophysical signature of mouse gamma motoneurons

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we identify key intrinsic properties underlying the distinct biophysical signature of gamma motoneurons (blue): a motoneuron subtype that innervates intrafusal muscle fibres (orange) to adjust spindle afferent (black) sensitivity for detecting muscle length changes during movement.
Simon A. Sharples, Struan J. Nisbet, Matthew J. Broadhead, Dennis Bo Jensen, Francesca L. Sorrell, Claire F. Meehan, Gareth B. Miles   +6 more
wiley   +1 more source

Alcohol addiction and Alzheimer's disease: a molecular collision course. [PDF]

Transl Psychiatry
Chang JS, Huang HZ, Yuan M, Zhou Y, Liu D, Zhan KB, Zhu LQ.   +6 more
europepmc   +1 more source

Expression Dynamics of Neurotransmitter System Genes in Early Sea Urchin Embryos: Insights from a Four-Species Comparative Transcriptome Analysis. [PDF]

Biology (Basel)
Shmukler YB, Alyoshina NM, Nikishina YO, Nikishin DA.   +3 more
europepmc   +1 more source

DISCRIMINATION BETWEEN CHOLINERGIC RECEPTORS IN RAT BRAIN AND TORPEDO CALIFORNICA ELECTROPLAX BY BINDING OF SNAKE VENOM TOXINS

, 1981
Ronald J. Lukas, Michael R. Hanley, Hiromi Morimoto, Edward L. Bennett   +3 more
openalex   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 8, Page 168-189, December 2025.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Targeting muscarinic receptors in schizophrenia treatment: Novel antipsychotic xanomeline/trospium chloride. [PDF]

World J Psychiatry
Pejčić AV.
europepmc   +1 more source

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Parkinson's disease (PD) and glioma are neurological disorders with distinct and even opposing mechanisms: α‐synuclein deposition and neuronal loss in PD versus glial cell malignancy in glioma. Despite these differences, their contrasting pathologies highlight multiple therapeutic targets.
Tianli Pan, Lin Yuan, Ruoyang Zhao, Liting Lu, Yinghao Zhi, Yuying Li, Min Wu, Yongye Huang   +7 more
wiley   +1 more source