Results 261 to 270 of about 2,429,018 (397)

Is Adipose Tissue Inflammation the Culprit of Obesity‐Associated Comorbidities?

Obesity Reviews, EarlyView.
ABSTRACT In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low‐grade inflammation.
Laurent Turner, Anjalee I. Wanasinghe, Pamela Brunori, Sylvia Santosa   +3 more
wiley   +1 more source

Editorial: Mechanisms of cholinergic transmission in motivation and cognition. [PDF]

Front Mol Neurosci
Francis TC, Klawonn AM.
europepmc   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism. [PDF]

Elife
Tubert C, Paz RM, Stahl AM, Sanchez Armijos KM, Rela L, Murer MG.   +5 more
europepmc   +1 more source

Neuroimmune pathophysiology of long COVID

Psychiatry and Clinical Neurosciences, EarlyView.
Although COVID‐19 was originally considered a respiratory illness, it is now well established that SARS‐CoV‐2 infection can have far‐reaching impacts on the nervous system. Neurological symptoms such as chemosensory dysfunction are frequently observed during acute infection and approximately 10% of COVID‐19 cases will go on to develop new or persistent
Janna K. Moen, Christopher A. Baker, Akiko Iwasaki   +2 more
wiley   +1 more source

Molecular organization of central cholinergic synapses. [PDF]

Proc Natl Acad Sci U S A
Rosenthal JS, Zhang D, Yin J, Long C, Yang G, Li Y, Lu Z, Li WP, Yu Z, Li J, Yuan Q.   +10 more
europepmc   +1 more source

[3H]benzylpempidine, a new radioligand for probing a putative channel site on nicotinic cholinergic receptors

, 1997
David X. Wang, Shey‐Shing Sheu, Virendra K. Sharma, Lisa E. Rubin, Michel Journet, Andrew S. Kende, Leo G. Abood   +6 more
openalex   +1 more source

The role of the oral microbiome, host response, and periodontal disease treatment in Alzheimer's disease: A primer

Periodontology 2000, EarlyView.
Abstract Background Alzheimer‘s disease (AD) is the leading cause of cognitive impairment and dementia in elderly patients worldwide. There is increasing evidence that periodontal disease may have an important role in the complex, multifactorial pathogenesis of AD. Aim This narrative review aims to (1) highlight the current understanding of the role of
Jaclyn C. Chalmers, Yvonne L. Hernandez‐Kapila   +1 more
wiley   +1 more source

Evaluation of the Alterations in Central Cholinergic Neurotransmission in Aging and Amyloid Precursor Protein Knock-In Mice. [PDF]

J Neurochem
Nagai-Arakawa I, Muramatsu I, Uwada J, Tsuda Y, Tokunaga A, Irie A, Maeda H, Madokoro Y, Sato T, Uchida Y, Saito T, Saido TC, Sada K, Masuoka T, Matsukawa N.   +14 more
europepmc   +1 more source