Results 271 to 280 of about 146,010 (350)

Exploring Adjunctive Novel Therapeutic Approach of KarXT (Xanomeline‐Trospium Chloride) for Managing Psychotic Symptoms in Patients With Schizophrenia and Alzheimer's Disease

Brain and Behavior, Volume 16, Issue 1, January 2026.
An overview of the mechanism of action, clinical trials, and classical findings of KarXT for the management of psychotic symptoms in patients with schizophrenia and alzheimer's disease. ABSTRACT Background Acute psychotic symptoms like delusions and hallucinations are of major concern while treating patients with schizophrenia and alzheimer's psychosis,
Ashir Kanwal, Bismah Azeem, Hania Nasir, Fatima Mumtaz, Nauman Ashraf, Mohammed Hammad Jaber Amin, Warisha Kanwal, Bilal Wazir Khan   +7 more
wiley   +1 more source

Cholinergic modulation mediates attentional mechanism to enhance coherence between cortical layers in macaque V1 and V4. [PDF]

Sci Rep
Sajedin A, FallahTaherpazir M, Menhaj MB.   +2 more
europepmc   +1 more source

Donepezil‐Induced Severe Anorexia and T‐Wave Inversion in Early‐Onset Alzheimer's Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Donepezil hydrochloride, used to treat Alzheimer's disease, is typically initiated at a low dose and titrated to minimize gastrointestinal side effects. Despite its favorable safety profile, the patient developed severe anorexia, dehydration, and electrocardiographic abnormalities.
Nobuyuki Takahashi, Takeshi Kuroda, Takashi Yoshioka, Hidetomo Murakami, Hironori Tanaka   +4 more
wiley   +1 more source

Complex opioid-driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward, and addiction. [PDF]

Elife
Chittajallu R, Vlachos A, Caccavano AP, Yuan X, Hunt S, Abebe D, London E, Pelkey KA, McBain CJ.   +8 more
europepmc   +1 more source

A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Sujan Tamang, Bishwo Ram Amatya, Sulav Neupane, Sunischit Chandra Neupane, Chiranjivi Panta, Anusmriti Pal, Dipesh Shrestha   +6 more
wiley   +1 more source

Altered Functional Specialization and Interhemispheric Coordination in Rhegmatogenous Retinal Detachment: Associations With Gene Expression, Neurotransmitter Receptor Distribution, and SVM–SHAP Classification

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Autonomy Index (AI) and Connective Flexibility of Homotopic voxels (CFH) were derived from resting‐state fMRI data following standard preprocessing. These functional metrics were computed based on the AAL90 atlas to characterize intrinsic activity and interhemispheric coordination patterns in RRD patients.
Yu Ji, Yuan‐Yuan Wang, Xiao‐Rong Wu
wiley   +1 more source

DISCRIMINATION BETWEEN CHOLINERGIC RECEPTORS IN RAT BRAIN AND TORPEDO CALIFORNICA ELECTROPLAX BY BINDING OF SNAKE VENOM TOXINS

, 1981
Ronald J. Lukas, Michael R. Hanley, Hiromi Morimoto, Edward L. Bennett   +3 more
openalex   +1 more source

Lineage‐Biased Neural Stem Cell Grafting Promotes Neuronal Differentiation and Vascular Repair in the Chronic Phase of Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Schematic diagram comparing two differentiation strategies to generate NSCs. The nEB‐NSCs exhibited a pronounced bias toward neuronal lineage differentiation. Transplantation of nEB‐NSCs into stroke mice (induced by tMCAO surgery) promoted motor recovery and vascular repair.
Tingting Zhang, Da Li, Qibiao Guan, Bin An, Yun Sun, Qiang Wang, Yukai Wang, Baoyang Hu   +7 more
wiley   +1 more source

Transmitter and ion channel profiles of saccadic omnipause neurons and cholinergic non-omnipause neurons in human nucleus raphe interpositus. [PDF]

Front Neuroanat
Mayadali ÜS, John M, Abspacher M, Schmitz C, Shaikh AG, Horn AKE.   +5 more
europepmc   +1 more source

The Direct Cholinomimetics and Cholinergic Blocking Agents Depend on Stereo Specificity of Cholinergic Receptors

Rezk R. Ayyad, Ahmed M. Mansour, Ahmed M. Nejm, Yasser Abdel Allem Hassan, Ahmed R. Ayyad   +4 more
openalex   +1 more source