Results 281 to 290 of about 146,010 (350)

Decreased 24‐hour Parasympathetic Activity following Intracerebral Hemorrhage: A Key Factor Correlated with Adverse Perihematomal Edema and Poor Functional Outcomes

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This study investigated associations between 24‐hour heart rate variability (HRV)‐assessed autonomic activity and perihematomal edema (PHE) development plus functional outcomes in 312 intracerebral hemorrhage (ICH) patients. Parasympathetic hypoactivity (low high‐frequency power) independently correlated with poor 3‐month outcomes (modified Rankin ...
Kaijiang Kang, Zeqiang Ji, Yunyi Hao, Jianwei Wu, Yani Zhang, Haiyan Li, Hui Lin, Yuhao Guo, Chuanying Wang, Yang Du, Guangshuo Li, Yongshi Yao, Yijun Lin, Zheng Liu, Jiexin Liu, Xingquan Zhao   +15 more
wiley   +1 more source

Acetylcholine in the gingival epithelium drives the pathogenesis of periodontitis. [PDF]

Front Cell Dev Biol
Xu S, Guo J, Yang S, Cheng B, Xia J.
europepmc   +1 more source

Effect of Anticholinergic Drug Burden on Postoperative Delirium in Elderly Patients: A Nested Case–Control Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This nested cohort study, nested within a multicentre prospective dataset of 6421 elective non‐cardiac surgery patients aged ≥ 65 years, tested whether pre‐operative anticholinergic burden predicts incident post‐operative delirium. Multivariable conditional logistic regression analysis revealed that each 1‐point increment in the Anticholinergic ...
Ting Zhang, Tianqi Shen, Ningxin Li, Xiaoying Zhang, Kai Zhang, Chang Liu, Bingbing Meng, Shaohua Zhang, Guangyu Tang, Ziyi Zhang, Qiang Fu, Yanhong Liu, Jingsheng Lou, Jiangbei Cao, Weidong Mi, Hao Li   +15 more
wiley   +1 more source

Comparative Analysis of Cholinergic Machinery in Carcinomas: Discovery of Membrane-Tethered ChAT as Evidence for Surface-Based ACh Synthesis in Neuroblastoma Cells. [PDF]

Int J Mol Sci
Thakur B, Tarazi S, Doležalová L, Behbahani H, Darreh-Shori T.   +4 more
europepmc   +1 more source

Reduced Neuronal Self‐Avoidance in Mouse Starburst Amacrine Cells With Only One Pcdhg Isoform

Developmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT The clustered protocadherins (cPcdhs) are a family of ∼60 homophilic cell adhesion molecules expressed across three gene clusters (Pcdha, Pcdhb, and Pcdhg) with a variety of essential roles in the developing nervous system. Some of these roles rely on specific isoforms, whereas others are more consistent with a model of isoform redundancy or a
Cathy M. McLeod, Seoyoung Son, Muhammad Nazmul Haque, Camille M. Hanes, Andrew M. Garrett   +4 more
wiley   +1 more source

Molecular mechanisms and therapeutic implications of the sympathetic nervous system in bone-related disorders: a brain-bone axis perspective. [PDF]

Bone Res
Liu M, Liu Y, Yu J, Gong J, Zhao C, Liu Z.   +5 more
europepmc   +1 more source

Activated microglial exosomes enhance α-Synuclein internalization and accelerate neurodegeneration in lewy body dementia. [PDF]

J Nanobiotechnology
Zhang M, You T, Guo M, Zhao Y, Shen W, Wang Y, Jiang Y, Dong Q, Yu J, Cui M, Zhao Y.   +10 more
europepmc   +1 more source

Neurexin regulates mechanical nociceptive sensitization by central inhibition in <i>Drosophila</i>. [PDF]

Sci Adv
Meng Z, Geng J, Sun Y, Xu L, Zhao Y, Ou M, Wang Y, Han J, Gu P, Xie W.   +9 more
europepmc   +1 more source

Characterization of optogenetically activated inhibitory inputs onto cholinergic motor neurons in the spinal dorsolateral nucleus. [PDF]

Physiol Rep
Kamijo TC, Karnup S, Matsuoka K, Kimura S, Miyazato M, Daugherty SL, Beckel JM, Yoshimura N.   +7 more
europepmc   +1 more source