Results 321 to 330 of about 2,429,018 (397)

Cholinergic Receptors and Addiction

Current topics in behavioral neurosciences, 2020
Human behavior can be controlled by physical or psychological dependencies associated with addiction. One of the most insidious addictions in our society is the use of tobacco products which contain nicotine. This addiction can be associated with specific receptors in the brain that respond to the natural neurotransmitter acetylcholine. These nicotinic
Mariella De Biasi, Roger L. Papke, Darlene H. Brunzell   +2 more
openaire   +4 more sources

Presynaptic muscarinic cholinergic receptors

Nature, 1978
IN the isolated rabbit heart, acetylcholine inhibits the release of noradrenaline evoked by nicotinic drugs1, by KCl (ref. 2) and by sympathetic nerve stimulation3. The release of noradrenaline in response to sympathetic nerve stimulation in the rabbit heart was found to be reduced by para-sympathomimetic agonists, and atropine antagonised this effect ...
Shailesh P. Banerjee, Virendra K. Sharma
openaire   +4 more sources

Acetylcarnitine and Cholinergic Receptors

Journal of Pharmaceutical Sciences, 1980
Acetylcarnitine, a naturally occurring compound found in high concentration in heart and skeletal muscle of vertebrates, bears structural resemblance to acetylcholine, and studies have shown that it has slight cholinergic properties. Acetylcarnitine was subjected to conformational analysis by extended Hückel theory (EHT) and complete neglect of ...
Wallace J. Murray, E.B. Roche, Kenneth W. Reed   +2 more
openaire   +3 more sources

Cholinergic receptors as target for cancer therapy in a systems medicine perspective.

Current molecular medicine, 2014
Epithelial cells not innervated by cholinergic neurons express nicotinic and muscarinic acetylcholine (ACh) receptors (nAChR, mAChR). nAChR and mAChR are components of the auto-/paracrine-regulatory loop of non-neuronal ACh release.
P. Russo, A. D. Bufalo, M. Milić, Gianluca Salinaro, M. Fini, A. Cesario   +5 more
semanticscholar   +1 more source

Cholinergic receptors in corpora cavernosa

Urology, 1984
In a group of 13 patients who underwent penile surgery, a small amount of cavernosal tissue was removed and examined for content of cholinergic receptors. Three patients did not display any amount of cholinergic receptors. Values in the other 10 patients ranged from 34 to 136 femtomols.
C.J. Godec, H. Bates
openaire   +3 more sources

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system.

Annual Review of Pharmacology and Toxicology, 2007
Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from numerous subunit combinations that compose channel-receptor complexes with varied functional and pharmacological characteristics. Structural and functional diversity and
J. Dani, D. Bertrand
semanticscholar   +1 more source

Studies on the nature of the cholinergic receptor

European Journal of Pharmacology, 1968
Abstract The effects of a number of proteolytic enzymes on the acetylcholine sensitivity of the chronically deniervated musue membrane and on the cholinesterase activity of the innervated end-plate were examined. None of the enzymes affected the acetylcholine sensitivity, but all of them inactivated cholinesterase.
B. Sonesson, M.D. Sokoll, E.X. Albuquerque, Stephen Thesleff   +3 more
openaire   +3 more sources

The functional role of cholinergic receptors in the outlet region of the urinary bladder: an in vitro study in the cat.

Acta Pharmacologica et Toxicologica, 2009
: A method for experimental study in vitro of the outlet region (bladder base, bladder neck and proximal urethra) from the cat is described which allows simultaneous recording of resistance to flow through the region and of isometric tension in the ...
A. Nergårdh, L. Boréus
semanticscholar   +1 more source

Immunohistochemistry of cholinergic receptors

Anatomy and Embryology, 1992
Acetylcholine and its receptors are involved in a variety of important signal transduction processes. As shown here paradigmatically for the human neuromuscular junction and the cerebral cortex, acetylcholine receptors can be visualized immunohistochemically at the cellular and subcellular level under physiological and pathological conditions.
openaire   +3 more sources

Adrenergic and cholinergic receptors in the human prostate, prostatic capsule and bladder neck.

British Journal of Urology, 1975
The adrenergic and cholinergic receptors of the human prostatic capsule, prostatic "adenoma", and bladder neck, were investigated by the in-vitro isometric technique.
M. Caine, Shlomo Raz, M. Zeigler
semanticscholar   +1 more source