Results 51 to 60 of about 140,463 (184)
A Dopamine-Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons [PDF]
, 2007 The "teaching signal" that modulates reinforcement learning at cortico-striatal synapses may be a sequence composed of an adaptively scaled DA burst, a brief ACh burst, and a scaled ACh pause.
Bullock, Daniel, Tan, Can Ozan
core +1 more source
Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels [PDF]
, 2006 It is known that glutamatergic and cholinergic systems interact functionally at the level of the cholinergic basal forebrain. The N-methyl-D-aspartate receptor (NMDA-R) is a multiprotein complex composed of NR1, NR2 and/or NR3 subunits.
Broide R.S. +11 more
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Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]
, 2020 Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S. +8 more
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Cholinergic neurons in the dorsomedial hypothalamus regulate food intake
Molecular Metabolism, 2017 Objective: Central cholinergic neural circuits play a role in the regulation of feeding behavior. The dorsomedial hypothalamus (DMH) is considered the appetite-stimulating center and contains cholinergic neurons.
Jae Hoon Jeong +2 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2020 Background: Extracellular ATP is a powerful trigger of neuroinflammation by activating immune cells via P2X7 receptors. Acetylcholine and nicotinic agonists inhibit ATP-triggered proinflammatory cytokines via the so-called “cholinergic anti-inflammatory ...
Dilyara Nurkhametova +11 more
doaj +1 more source
Effect of gallamine on cholinergic receptors [PDF]
Canadian Anaesthetists’ Society Journal, 1970 Gallamine triethiodide causes tachycardia thought to be due to a specific vagolytic action. Recently, Brown and Crout have shown that gallamine may cause increased inotropic and chronotropic activity due to the release of catecholamines from cardiac sympathetic nerves.
F J, Rathbun, J T, Hamilton
openaire +2 more sources
Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
, 2007 Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
core +1 more source
New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
core +4 more sources
Frontiers in Molecular NeuroscienceObjectiveAcetylcholine modulates the activity of the direct and indirect pathways within the striatum through interaction with muscarinic M4 and M1 receptors.
Anna Berezovskaia +10 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2017 The degeneration of cholinergic neurons of the nucleus basalis of Meynert (NBM) in the basal forebrain (BF) is associated to the cognitive decline of Alzheimer’s disease (AD) patients. To date no resolutive therapies exist. Cell-based replacement therapy
Annamaria Morelli +18 more
doaj +1 more source