Results 121 to 130 of about 198,632 (298)

Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons

Molecular Neurodegeneration, 2010
Background Septal cholinergic neurons account for most of the cholinergic innervations of the hippocampus, playing a key role in the regulation of hippocampal synaptic activity.
Inestrosa Nibaldo C, Pissani Claudia A, Mauna Jocelyn C, Lazo Oscar M, Bronfman Francisca C   +4 more
doaj   +1 more source

In vivo cholinergic system integrity and cognition using [18F]‐FEOBV PET in healthy postmenopausal women: a pilot study [PDF]

, 2022
Alexander C. Conley, Tonnar Castellano, Brian D. Boyd, John P. Begnoche, Adam J. Rosenberg, Sepideh Shokouhi, Julie Dumas, Paul Newhouse   +7 more
openalex   +1 more source

Regenerative Medicine for the Aging Brain [PDF]

, 2014
In the central nervous system, cholinergic and dopaminergic (DA) neurons are among the cells most susceptible to the deleterious effects of age. Thus, the basal forebrain cholinergic system is known to undergo moderate neurodegenerative changes during ...
Goya, Rodolfo Gustavo, Hereñú, Claudia Beatriz, López León, Micaela, Reggiani, Paula Cecilia   +3 more
core   +2 more sources

Wuda Granule Improves the Gastrointestinal Motility via Gut‐Brain Axis in Beagle Dogs

iMetaMed, EarlyView.
Stress sensors were implanted in the gastric body, sinus, duodenum, jejunum, and colon of beagle dogs to record gastrointestinal motility. Gastrointestinal contractile motility was assessed before and after the lateral ventricular injection of Wuda granule, intravenous atropine instillation, and bilateral cervical vagotomy.
Zhi Jiang, Xing Li, Qicheng Chen, Zhiqiang Chen, Lixing Cao, Hailin Tang   +5 more
wiley   +1 more source

Acetylcholinesterase-Positive Fiber Deafferentation and Cell Shrinkage in the Septohippocampal Pathway of Aged Amyloid Precursor Protein London Mutant Transgenic Mice

Neurobiology of Disease, 2000
Several lines of evidence implicate a cholinergic deficit in Alzheimer's disease (AD). Transgenic mice that overexpress clinical mutants of the human amyloid precursor protein (APP) have been generated that recapitulate many aspects of AD.
Francisca C. Bronfman, Dieder Moechars, Fred Van Leuven   +2 more
doaj   +1 more source

Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems [PDF]

, 1993
Emmanuel Mignot, Seiji Nishino, LH Sharp, Janis Arrigoni, JM Siegel, M. S. Reid, DM Edgar, RD Ciaranello, Dement Wc   +8 more
openalex   +1 more source

The Oxidative Stress of Mercaptan Odorant Due to Occupational Exposure: Adverse Effects on the Cholinergic System [PDF]

, 2022
Rezvan Zendehdel, Shirin Seyed Ghoreyshi, Fatemeh Rajabi, Zohreh Amini, Majid Mahdian Dehkordi, Hakimeh Nouri Parkestani   +5 more
openalex   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U, Zuzanna M. Baran, Pascal Coumailleau, Laetitia Guillot, Harry W. M. Steinbusch, Fatima Smagulova, Thierry D. Charlier   +6 more
wiley   +1 more source

Interaction of the renin–angiotensin system, bradykinin and sympathetic nerves with cholinergic transmission in the rat isolated trachea [PDF]

, 1997
Maurice E. Fabiani, Diem Dinh, David Story   +2 more
openalex   +1 more source

Long‐Term Real‐World Effectiveness of Rupatadine in Chronic Urticaria: A Retrospective Observational Study

JEADV Clinical Practice, EarlyView.
This retrospective observational study analyzed a cohort of chronic urticaria (CU) patients to provide insight into the clinical practice of CU with second‐generation antihistamines (SgAHs) and to evaluate the long‐term real‐world effectiveness of rupatadine in CU. Patients with chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU)
A. M. Giménez‐Arnau, C. Romero, M. March, A. Tomas, I. Izquierdo, R. M. Pujol   +5 more
wiley   +1 more source