Results 141 to 150 of about 131,181 (262)

Pathophysiology, Therapeutic Targets, and Future Therapeutic Alternatives in COPD: Focus on the Importance of the Cholinergic System. [PDF]

Biomolecules, 2023
Gomes F, Cheng SL.
europepmc   +1 more source

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

An endogenous cholinergic system controls electrical conduction in the heart. [PDF]

Eur Heart J
Xie D, Xiong K, Dong N, Wang G, Zou Q, Shao B, Chen Z, Wang L, Kong Y, Wang X, Su X, Bai W, Yang J, Liu Y, Zhou B, Chen YH.   +15 more
europepmc   +1 more source

Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches. [PDF]

Lancet Neurol, 2022
Bohnen NI, Yarnall AJ, Weil RS, Moro E, Moehle MS, Borghammer P, Bedard MA, Albin RL.   +7 more
europepmc   +1 more source

Pathogenesis of hidradenitis suppurativa: From susceptibility to chronicity

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review describes hidradenitis suppurativa as a heterogeneous disorder in which genetic susceptibility, epithelial dysfunction, environmental exposures, immune activation and microbial ecology converge differently across patients and disease stages.
Kelsey R. van Straalen, Nisha S. Chandran, Jean M. Fletcher, Evangelos J. Giamarellos‐Bourboulis, Elia Rosi, Gregor B. E. Jemec   +5 more
wiley   +1 more source

Hierarchical organization of the forebrain cholinergic system in rats. [PDF]

iScience
Varsanyi P, Alloway K, Chavez C, Gielow MR, Gombkoto P, Kondo H, Nadasdy Z, Zaborszky L.   +7 more
europepmc   +1 more source

Social Isolation: How Can the Effects on the Cholinergic System Be Isolated? [PDF]

Front Pharmacol, 2021
Myslivecek J.
europepmc   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Role of the cholinergic system in the psychopathology and treatment of schizophrenia: a protocol for a scoping review. [PDF]

Front Psychiatry
Haczkiewicz M, Hylén U, Msghina M.
europepmc   +1 more source

Individual differences in set‐shifting and levodopa responsiveness in Parkinson's disease

Journal of Neuropsychology, EarlyView.
Abstract Perseveration (PE) and learned irrelevance (LI) are two distinct processes that shape attentional set‐shifting in Parkinson's disease (PD). Whether LI and PE are dopamine‐dependent remains unclear. We investigated whether PE and LI may be dissociated in early PD and whether these switch conditions are associated with an individual motor ...
Aleksandra Fijałkiewicz, Krzysztof Batko, Małgorzata Dec‐Ćwiek, Karolina Porębska, Barbara Bętkowska‐Korpała, Aleksandra Gruszka   +5 more
wiley   +1 more source