Results 171 to 180 of about 131,181 (262)

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

Oral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung, Soohyun Kim, Yoo‐Bin Kim, Hee‐Kyung Park, Se‐Young Choi   +4 more
wiley   +1 more source

Mini Review: the non-neuronal cardiac cholinergic system in type-2 diabetes mellitus. [PDF]

Front Cardiovasc Med
Saw EL, Fronius M, Katare R, Kakinuma Y.
europepmc   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Editorial: The non-neuronal cholinergic system in the cardiovascular system: its influence on the heart, vasculature, and the central nervous system. [PDF]

Front Cardiovasc Med
Kakinuma Y, Sonobe T, Katare R.
europepmc   +1 more source

Finding the Words: How Does the Aging Brain Process Language? A Focused Review of Brain Connectivity and Compensatory Pathways

Topics in Cognitive Science, EarlyView.
Abstract As people age, there is a natural decline in cognitive functioning and brain structure. However, the relationship between brain function and cognition in older adults is neither straightforward nor uniform. Instead, it is complex, influenced by multiple factors, and can vary considerably from one person to another.
Monica Baciu, Elise Roger
wiley   +1 more source

Associations of cholinergic system integrity with cognitive decline in GBA1 and LRRK2 mutation carriers. [PDF]

NPJ Parkinsons Dis
Schumacher J, Ray N, Teipel S, Storch A.
europepmc   +1 more source

Cerebrovascular flow‐mediated dilation in humans: Methodological challenges, physiological interpretation and future integrations

Experimental Physiology, EarlyView.
Abstract Arterial shear‐mediated vasodilation is a well‐established measure of endothelial function and serves as a critical biomarker for cardiovascular disease risk. Endothelial function can be measured using a variety of experimental methodologies; however, the most widely adopted technique is ultrasound‐based flow‐mediated dilation (FMD), in which ...
Yi Zhen Bao, Tabitha V. Craig, Jenna C. McCrone, Kurt J. Smith, Michael M. Tymko   +4 more
wiley   +1 more source

The Effects of Co-Exposure to Antifoulants and Microplastics on the Survival, Oxidative Status, and Cholinergic System of a Marine Mysid. [PDF]

Toxics
Lee S, Haque MN, Lee DH, Rhee JS.
europepmc   +1 more source

Peripheral non‐invasive focused ultrasound alleviates constipation by reducing gastrointestinal inflammation

Experimental Physiology, EarlyView.
Abstract Constipation affects approximately 20% of the US population, with diverse treatment options available due to the unclear onset and causes of the condition. Recently, focused ultrasound (FUS) has been proposed as a novel, non‐invasive peripheral neuromodulatory treatment that may reduce this inflammation.
Dia Shah, Kainat Akhtar, Dev Dwivedi, Amal Siddiqui, Griffin Haggas, Nicole Forman, Tatiana Gervase, Yifan Kao, John Chen, Julia Brzac, Eric Molho, Damian Shin   +11 more
wiley   +1 more source