Equine Veterinary Journal, EarlyView.Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
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The effect of trimedoxime on acetylcholinesterase and on the cholinergic system of the rat bladder [PDF]
, 2010 Ondřej Soukup +7 more
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Protective role of acetylcholine and the cholinergic system in the injured heart. [PDF]
iScienceLiu Chung Ming C, Wang X, Gentile C.
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The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline. [PDF]
Int J Mol Sci, 2023 Carlson EC +4 more
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TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models
The FEBS Journal, EarlyView.The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir +7 more
wiley +1 more source
Vagus nerve stimulation recruits the central cholinergic system to enhance perceptual learning. [PDF]
Nat NeurosciMartin KA +10 more
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The Cholinergic System, the Adrenergic System and the Neuropathology of Alzheimer's Disease. [PDF]
Int J Mol Sci, 2021 Bekdash RA.
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The FEBS Journal, EarlyView.Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua +2 more
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The basal forebrain cholinergic system as target for cell replacement therapy in Parkinson's disease. [PDF]
BrainBjörklund A, Barker RA.
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Molecular Imaging of the Cholinergic System in Alzheimer and Lewy Body Dementias: Expanding Views. [PDF]
Curr Neurol Neurosci Rep, 2021 Kanel P +6 more
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