Results 211 to 220 of about 131,181 (262)
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The cholinergic system in Down's syndrome
Journal of Intellectual Disabilities, 2006The cholinergic system is one of the most important modulatory neurotransmitter systems in the brain. Alterations of the transmission communicators are accompanied by reduction of the cortical activity, which is associated with a learning and memory deficit.
Giovanni Grasso, Vincenzo Fodale
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Cannabinoids And The Cholinergic System
The Journal of Clinical Pharmacology, 1981Abstract: Δ9‐Tetrahydrocannabinol (THC) decreases EEG activation and causes slow waves in the cat. The EEG slow‐wave activity is accompanied by a concomitant decrease in acetylcholine release from the neocortex. The findings suggest that THC depresses the brain stem activating system. Large doses of Δ8‐ and Δ‐THC increase brain acetylcholine levels in
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Cholinergic system and cell proliferation
Chemico-Biological Interactions, 2016The cholinergic system, comprising acetylcholine, the proteins responsible for acetylcholine synthesis and release, acetylcholine receptors and cholinesterases, is expressed by most human cell types. Acetylcholine is a neurotransmitter, but also a local signalling molecule which regulates basic cell functions, and cholinergic responses are involved in ...
F J, Campoy +5 more
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The cholinergic system in Alzheimer's disease
Progress in Neurobiology, 1997The past decade has witnessed an enormous increase in our knowledge of the variety and complexity of neuropathological and neurochemical changes in Alzheimer's disease. Although the disease is characterized by multiple deficits of neurotransmitters in the brain, this overview emphasizes the structural and neurochemical localization of the elements of ...
P, Kása, Z, Rakonczay, K, Gulya
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The cholinergic system and hippocampal plasticity
Behavioural Brain Research, 2011Acetylcholine is an essential excitatory neurotransmitter in the central nervous system and undertakes a vital role in cognitive function. Consequently, there is ample evidence to suggest the involvement of both nicotinic and muscarinic acetylcholine receptors in the modulation of synaptic plasticity, which is believed to be the molecular correlate of ...
Benjamin D, Drever +2 more
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Modulation of cholinergic systems by manganese
NeuroToxicology, 2007Information on changes in the central nervous system (CNS) cholinergic systems following exposure to manganese are considerably less extensive than that associated with other neurotransmitter systems. However, experimental and clinical evidence support the notion that cholinergic activity plays a key role in the pathophysiology of manganese-induced ...
Yoram, Finkelstein +2 more
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CENTRAL CHOLINERGIC SYSTEMS AND COGNITION
Annual Review of Psychology, 1997▪ Abstract The organization and possible functions of basal forebrain and pontine cholinergic systems are reviewed. Whereas the basal forebrain cholinergic neuronal projections likely subserve a common electrophysiological function, e.g. to boost signal-to-noise ratios in cortical target areas, this function has different effects on psychological ...
B J, Everitt, T W, Robbins
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The cholinergic system and spatial learning
Behavioural Brain Research, 2011Acetlylcholine (ACh) in the central nervous system is critical for a multitude of functions. Here, we concentrate on declarative memory in humans, and its equivalent episodic-like memory in rodents and highlight current understanding of cholinergic system in these processes.
Serena, Deiana +2 more
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Developmental aspects of the cholinergic system
Behavioural Brain Research, 2011Beyond its importance in sustaining or modulating different aspects of the activity of the central nervous system (CNS), the cholinergic system plays important roles during development. In the current review, we focus on the developmental aspects associated with major components of the cholinergic system: Acetylcholine, choline acetyltransferase ...
Yael, Abreu-Villaça +2 more
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Cholinergic Systems and Multiple Cholinergic Receptors in Ocular Tissues
Journal of Ocular Pharmacology and Therapeutics, 1985Acetylcholine (ACh), choline acetyltransferases and cholinesterases occur in cornea, iris-ciliary body complex and retina of several vertebrates. In cornea, ACh may serve as a sensory transmitter as well as a local hormone, the function of which is not delineated.
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