Results 131 to 140 of about 49,840 (263)

Baseline characteristics from evoke and evoke+: Two phase 3 randomized placebo‐controlled trials of semaglutide in participants with early‐stage symptomatic Alzheimer's disease

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION The glucagon‐like peptide‐1 receptor agonist semaglutide may impact neuroinflammation and reduce neurodegeneration. We present baseline characteristics of participants enrolled in the evoke (NCT04777396) and evoke+ (NCT04777409) trials, referred to as “evoke (+)” hereafter.
Philip Scheltens   +10 more
wiley   +1 more source

Gallic Acid, 3-Hydroxytyrosol, and Quercetin Modulate Cholinesterase Activity in <i>Drosophila melanogaster</i>. [PDF]

open access: yesInt J Mol Sci
Ucar Akyurek T   +5 more
europepmc   +1 more source

Blood biomarkers for Alzheimer's disease are correlated with measures of agitation and cognition in a randomized trial assessing the effects of escitalopram on agitation

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Escitalopram for Agitation in Alzheimer's Disease (S‐CitAD) is a National Institutes of Health–funded randomized controlled trial that randomized 173 participants with clinically diagnosed Alzheimer's disease (AD) and agitation to escitalopram or placebo for 12 weeks, assessing efficacy and safety.
Maansi Barnwal   +9 more
wiley   +1 more source

Impact of Frailty on the Prognosis of Patients With Liver Cirrhosis Undergoing Insertion of a TIPS

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 1, Page 109-118, January 2026.
In patients with cirrhosis undergoing TIPS, frailty—measured by the Liver Frailty Index—improved in those with poor baseline status; therefore, high frailty should not be seen as a contraindication to elective TIPS. Additionally, LFI assessment before TIPS enables identification of patients with excellent survival prognosis.
Martin Andreas Kabelitz   +16 more
wiley   +1 more source

Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
We investigated the association between tricuspid regurgitation (TR) severity and hepatic T1‐time in 1029 patients undergoing cardiac MRI and echocardiography. Hepatic T1‐time increased progressively with TR severity and remained independently associated after adjusting for NT‐proBNP and right ventricular function. Both TR and hepatic T1‐time predicted
Katharina Mascherbauer   +19 more
wiley   +1 more source

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