Results 211 to 220 of about 129,913 (308)

Dual-Lineage Chondrocyte-Like Cells in the Nucleus Pulposus of Aging Intervertebral Discs Are Accelerated by Hedgehog Signaling Inactivation. [PDF]

Aging Cell
Zhang L, Xiu C, You H, Chen J.
europepmc   +1 more source

Bone morphogenic protein (BMP-2) enhances expression of type II collagen and aggrecan in human chondrocytes in 3D alginate cultures [PDF]

, 2004
WK Aicher, B Thunemann, C. Gaissmaier, J Fritz, Tatiana Gründer   +4 more
openalex   +1 more source

Mimicking DOUGONG brackets orchestrate regulating inflammation and mechanical stimuli for osteochondral regeneration using 3D printing

Interdisciplinary Medicine, EarlyView.
Akermanite scaffolds promote osteogenic differentiation of BMSCs through regulating the PI3K/Akt signaling pathway, and strontium ions enhance the akermanite effects by mediating the cytokine‐cytokine receptor interaction pathway. Thus, the enhancements of osteogenesis in subchondral bone coupled with the chondral‐promoting effects of chondrocytes ...
Bo Li, Yaqi Zhang, Xuerui Zhou, Weiguo Wang, Fan Yang, Qiushi Wei, Leilei Chen, Ziqi Li, Mincong He, Xiaoming He, Shengting Chai, Xiuhong Cao, Rui Wang, Tongmeng Jiang, Chen Wang, Wei He   +15 more
wiley   +1 more source

Astragaloside IV Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis via the p53/SLC7A11/GPX4 Axis. [PDF]

J Inflamm Res
Tang Z, Cheng L, Li M, Chen J, Huang C.
europepmc   +1 more source

Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis.

Journal of Clinical Investigation, 2016
Minjie Zhang, Sriniwasan B. Mani, Yao He, A. Hall, Lin Xu, Yefu Li, D. Zurakowski, G. Jay, M. Warman   +8 more
semanticscholar   +1 more source

In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I)

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes.
Victoria P. Marino, Francesca De Vecchi, Takayuki Koya, Landon M. Begin, Douglas C. Moore, Joseph J. Crisco, Markus A. Wimmer   +6 more
wiley   +1 more source

AMPK signaling in osteoarthritis: from mechanisms to targeted therapeutics. [PDF]

Front Pharmacol
Chen L, Hu XH, Wu XY, Zhang X, Han YX, Liu Y, Chen GY, Tao QW.   +7 more
europepmc   +1 more source

In Vivo Evaluation of Hemiarthroplasty Bearing Materials Using Animal Models: A Scoping Review (Part II)

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Hemiarthroplasty is commonly used to treat damage localized to one side of a synovial joint, maximally preserving the patient's opposing healthy bone and cartilage; however, challenges remain due to accelerated wear of the cartilage articulating with the implant surface. This scoping review summarized investigations of hemiarthroplasty bearing
Landon M. Begin, Victoria P. Marino, Francesca De Vecchi, Douglas C. Moore, Markus A. Wimmer, Joseph J. Crisco   +5 more
wiley   +1 more source

CAP-CD56⁺CD271⁺ BMSCs exos-loaded PVA/SA sustained-release hydrogel attenuates chondrocyte senescence and ameliorates lumbar facet joint osteoarthritis. [PDF]

Bioact Mater
Xie Y, Liu Q, Tan J, Lu Y, Li Y, Ye H, Xu Z, Wang M, Wang C, Li X, Xue J, Yan Y.   +11 more
europepmc   +1 more source

Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator. Bone mineral density (BMD), bone volume/total volume
Qing Su, Jia Chen
wiley   +1 more source