Results 311 to 320 of about 118,065 (344)
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1995
Data obtained while investigating growth plate chondrocyte differentiation during endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis depends on positional signaling mediated by selected homeobox-containing genes and soluble mediators.
R, Cancedda +2 more
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Data obtained while investigating growth plate chondrocyte differentiation during endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis depends on positional signaling mediated by selected homeobox-containing genes and soluble mediators.
R, Cancedda +2 more
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A biography of the chondrocyte
Annals of the Rheumatic Diseases, 2008Significant gaps persist in our understanding of chondrocyte biology. We do not know when, how, or even whether these cells are replenished throughout the normal, human life span. We are taught that as much as 90% of the cartilage is "metabolically inert" interterritorial matrix, but we do not know how this substance is regularly replaced (as it is ...
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In situ chondrocyte viscoelasticity
Journal of Biomechanics, 2012It has been proposed, based on theoretical considerations, that the strain rate-dependent viscoelastic response of cartilage reduces local tissue and cell deformations during cyclic compressions. However, experimental studies have not addressed the in situ viscoelastic response of chondrocytes under static and dynamic loading conditions. In particular,
Ziad Abusara +3 more
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Prevention of Chondrocyte Apoptosis
The Journal of Bone and Joint Surgery-American Volume, 2001The occurrence of chondrocyte apoptosis may be critical in determining the extent of a lesion and subsequent repair after mechanical injury to articular cartilage. Agents that prevent apoptosis and increase chondrocyte survival may prove beneficial in the treatment of these lesions.
Darryl D. D'Lima +4 more
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Tissue Engineering with Chondrocytes
Facial Plastic Surgery, 2002Tissue engineering of cartilage, using chondrocytes based on the use of synthetic biodegradable polymer cell delivery vehicles (scaffolds), is an alternate treatment modality for replacing missing cartilage. Cartilage tissue engineering has an important role to play in the generation of graft material for head and neck reconstruction. It is an approach
R. James Koch, Goutham Krishna Gorti
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Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial.
Journal of Bone and Joint Surgery. American volume, 2004BACKGROUND New methods have been used, with promising results, to treat full-thickness cartilage defects. The objective of the present study was to compare autologous chondrocyte implantation with microfracture in a randomized trial.
G. Knutsen +9 more
semanticscholar +1 more source
Phenotype of chondrocytes in osteoarthritis
Biorheology, 2008Articular cartilage is composed by a unique cell population, the chondrocytes, embedded in an abundant extra-cellular matrix (ECM). Growth, differentiation and homeostasis of the cartilage are regulated by an intricate interplay between the chondrocytes and ECM, which allows the matrix to send signals to the chondrocytes and the chondrocytes to sense ...
IANNONE, Florenzo, LAPADULA, Giovanni
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Mitochondrial granules in chondrocytes
Calcified Tissue Research, 1969Rat and mice epiphyseal growth plates were studied with the electron microscope. A gradient of mitochondrial electron-dense granules was found. Chondrocytes in the proliferative zone had few granules, while those of the succeeding zones showed a gradual increase in number and density until the zone of provisional calcification was reached.
J. H. Martin, J. L. Matthews
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Small, 2017
Utilizing biomaterials to regulate the phenotype and proliferation of chondrocytes is a promising approach for effective cartilage tissue regeneration.
X. Shao +6 more
semanticscholar +1 more source
Utilizing biomaterials to regulate the phenotype and proliferation of chondrocytes is a promising approach for effective cartilage tissue regeneration.
X. Shao +6 more
semanticscholar +1 more source
LncRNA PVT1 Regulates Chondrocyte Apoptosis in Osteoarthritis by Acting as a Sponge for miR-488-3p.
DNA and Cell Biology, 2017Long noncoding RNAs (lncRNAs) have been known to be involved in multiple diverse diseases, including osteoarthritis (OA). The present study aims at exploring the biological role of lncRNA plasmacytoma variant translocation 1 (PVT1) in OA and the ...
Yufei Li +4 more
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