Results 321 to 330 of about 118,065 (344)
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Single cilia in chondrocytes

Journal of Ultrastructure Research, 1967
Electron microscopic investigation of embryonic mouse radii reveals that chondrocytes in epiphyseal cartilage can form single cilia. The cilia can be distinguished from ordinary microvilli by their greater length and the organization of their bases, which are formed by a centriole accompanied by a second one in the near neighborhood.
J.P. Scherft, W. Th. Daems
openaire   +3 more sources

Autologous chondrocyte transplantation

Operative Techniques in Sports Medicine, 2000
Since its introduction in 1987, autologous chondrocyte transplantation (ACT) for the management of full-thickness chondral defects of the knee has gained considerable attention and has renewed interest in cartilage repair. At this time there are patients with 10 to 13 years of follow-up who have continued to benefit from ACT.
Lars Peterson, Tom Minas
openaire   +2 more sources

Chondrocytes in Aging Research

1979
Publisher Summary Chondrocytes or cells derived from cartilaginous tissues represent a highly differentiated cell type and they synthesize and secrete a unique and specific protein, Type II collagen. Collagen synthesis is studied in a variety of systems utilizing cells derived from different tissues of a number of species. Populations of chondrocytes
E J, Miller, S, Gay
openaire   +3 more sources

Chondrocyte Culture and Assay

Current Protocols in Pharmacology, 2001
AbstractChondrocytes constitute the sole cell type found within cartilage, and control the formation and composition of cartilage. Cellular, biochemical and pharmacological studies of arthritis and other cartilage disorders have increasingly focused on chondrocyte function.
Ronald L. Goldberg, Jeffrey M. Liebman
openaire   +3 more sources

Autologous chondrocyte implantation in the knee: mid-term to long-term results.

Journal of Bone and Joint Surgery. American volume, 2014
BACKGROUND From 1998 to 2008, 1000 skeletally mature patients underwent autologous chondrocyte implantation for an osteochondral defect of the knee. We evaluated the functional outcomes in 827 of 869 patients who had undergone autologous chondrocyte ...
S. Z. Nawaz   +6 more
semanticscholar   +1 more source

The breakdown of collagen by chondrocytes

The Journal of Pathology, 1980
The chondrocytes of pure articular cartilage from young pigs display collagenolytic activity when the cartilage is cultivated by an organ culture method in medium containing 5--10 IU retinol/ml. Breakdown of collagen occurs in all regions of the cartilage; in the thicker explants it is greatest and most frequent in those that contain the deepest zone ...
Honor B. Fell, R. W. Jubb
openaire   +3 more sources

Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels.

Journal of Biomechanical Engineering, 2000
Due to its avascular nature, articular cartilage exhibits a very limited capacity to regenerate and to repair. Although much of the tissue-engineered cartilage in existence has been successful in mimicking the morphological and biochemical appearance of ...
R. Mauck   +7 more
semanticscholar   +1 more source

Culture of Immortalized Chondrocytes and Their Use As Models of Chondrocyte Function

2004
Immortalization of chondrocytes increases life span and proliferative capacity but does not necessarily stabilize the differentiated phenotype. Expansion of chondrocyte cell lines in continuous monolayer culture may result in the loss of phenotype, particularly if high cell density is not maintained. This chapter describes strategies for maintaining or
openaire   +3 more sources

Growth factor responsiveness of human articular chondrocytes: Distinct profiles in primary chondrocytes, subcultured chondrocytes, and fibroblasts

Journal of Cellular Physiology, 1994
AbstractThe objectives of this study were to establish a growth factor response profile for adult human articular chondrocytes, to determine whether this is unique for chondrocytes or influenced by the differentiation status of the cells, and to characterize growth factor interactions.
Pierre-André Guerne   +2 more
openaire   +3 more sources

A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years.

Journal of Bone and Joint Surgery. American volume, 2007
BACKGROUND The optimal treatment for cartilage lesions has not yet been established. The objective of this randomized trial was to compare autologous chondrocyte implantation with microfracture.
G. Knutsen   +9 more
semanticscholar   +1 more source

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